Fig. 4From: Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniaeCoumarin decreased the expression of carbapenemase genes as revealed by qRT-PCR. The influence of sub-MIC of coumarin on the relative expression of caerbapenemase genes (blaVIM−2, blaNDM−1 and blaOXA−9). The data represent the mRNA expression of each gene both in presence and absence of coumarin. The expression values were normalized using the 16 S rRNA as a house keeping gene. *** Indicates significance at P < 0.001Back to article page