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Fig. 3 | BMC Microbiology

Fig. 3

From: Establishment of an in vitro model of monocyte-like THP-1 cells for trained immunity induced by bacillus Calmette-Guérin

Fig. 3

Transcriptomic analysis of BCG-EGFP-infected non-adherent THP-1 cells. a The network of GO terms. Top 16 clusters with their representative enriched terms (one per cluster). The “count” is the number of genes present in the given ontology term, colored by cluster ID, where nodes that share the same cluster ID are typically close to each other. b The bubble chart of top 10 KEGG pathways. Enriched pathways of up-regulated and down-regulated DEGs were ranked by gene ratio (i.e. mapped gene number/pathway gene number). c The GSEA plots associated with trained immunity. Genes are ranked by Signal2Noise in GSEA plot. Gene expression levels decreased from left (red) to right (blue). The matching gene expression heatmaps were shown beneath. Gene expression values were normalized to z-score

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BMC Microbiology

ISSN: 1471-2180

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