Fig. 1From: Anti-Acinetobacter baumannii single-chain variable fragments provide therapeutic efficacy in an immunocompromised mouse pneumonia modelEB211 and EB279 caused no toxicity to the kidneys and liver of mice. No noticeable histopathological changes were observed in the kidneys and liver of mice injected intraperitoneally twice daily with EB211 (12Â mg/kg), EB279 (12Â mg/kg), or a cocktail of the two scFvs (CKT;Â 6Â mg/kg of each) for 72Â h, similar to mice injected intraperitoneally twice daily with colistimethate sodium (CMS; 30Â mg/kg) or normal saline (NS). Green arrowheads: sinusoids, V: central venules, Yellow arrowheads: hepatocytes, Yellow arrows: renal tubule and renal corpuscleBack to article page