Table 3 Transcripts significantly induced in mouse blood in response to B. burgdorferi
Unigene | Gene symbol | Gene title | Gene ontology | FCaB515 | FCaB331 |
|---|---|---|---|---|---|
Transcripts induced by B. burgdorferi B515 | |||||
Mm. 387173 | Chi3l3 | chitinase 3-like 3 | Inflammatory response | 9.14 | 1.17 |
Mm.9537 | Lcn2 | lipocalin 2 | Response to virus | 7.25 | −1.43 |
Mm.236225 | Ngp | neutrophil granule protein | Defense response to bacterium | 5.64 | −1.20 |
Mm.16415 | Mmp8 | matrix metallopeptidase 8 | Proteolysis | 5.21 | 1.01 |
Mm.1349 | Il1r2 | Interleukin 1 receptor, type II | Lipid metabolic process | 4.78 | −1.02 |
|  | Ighg | Immunoglobulin heavy chain (gamma polypeptide) |  | 4.23 | −1.08 |
Mm.158700 | Vcan | versican | Cell adhesion, heart development | 4.10 | 1.20 |
Mm.248327 | Clec4e | C-type lectin domain family 4, member e | Immune response | 4.03 | 1.11 |
Mm.3834 | Camp | cathelicidin antimicrobial protein | Defense response to bacterium | 3.96 | −1.09 |
Mm.274927 | Ccr1 | chemokine (C-C) receptor 1 | Inflammatory response | 3.68 | −0.05 |
Mm.24208 | Il13ra1 | interleukin 13 receptor, alpha 1 | Cytokine-mediated signaling pathway | 3.63 | 1.15 |
Mm.477887 | Fpr2 | formyl peptide receptor 2 | G-protein coupled receptor signaling | 3.62 | −1.35 |
Mm.282359 | Ltf | lactotransferrin | Iron ion transport, homeostasis | 3.60 | −1.15 |
Mm.248360 | Anxa1 | annexin A1 | Leukocyte homeostasis | 3.45 | −1.26 |
Mm.9277 | Pla2g7 | phospholipase A2, group VII | Inflammatory response | 3.41 | 1.14 |
Mm.882 | Il1rn | interleukin 1 receptor antagonist | Negative regulation of cytokine-mediated signaling | 3.30 | 1.25 |
Mm.87596 | Tlr2 | toll-like receptor 2 | Pattern recognition receptor signaling pathway | 3.01 | −1.12 |
Mm.276440 | Ifitm6 | interferon induced transmembrane protein 6 | Response to biotic stimulus | 3.00 | −1.30 |
Mm.143718 | Mefv | Mediterranean fever | Inflammatory response | 2.93 | 1.09 |
Mm.19131 | C3 | complement component 3 | Inflammatory response, innate | 2.91 | −1.04 |
Mm.486 | Lamp2 | lysosomal-associated membrane protein 2 |  | 2.89 | −1.09 |
Mm.336203 | Tlr13 | toll-like receptor 13 | Inflammatory response, signal Transduction | 2.72 | −1.22 |
Mm.3460 | Cd14 | CD14 antigen | Response to molecule of bacterial origin | 2.60 | −1.44 |
Mm.170515 | Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha | Protein import into nucleus, Translocation | 2.55 | −1.29 |
Mm.47384 | Clec4a2 | C-type lectin domain family 4, member a2 | Immune response | 2.48 | 1.10 |
Mm.379266 | Ifitm2 | interferon induced transmembrane protein 2 | Response to biotic stimulus | 2.41 | −1.22 |
Transcript induced by B. burgdorferi B331 | |||||
Mm247642 | Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain | Signal transduction | 1.71 | 2.02 |