Figure 6From: Mitogen-activated protein kinase Hog1 is activated in response to curcumin exposure in the budding yeast Saccharomyces cerevisiae Proposed model showing molecular mode of action of CUR on S. cerevisiae. After entering into yeast cells CUR causes activation of osmotic stress. We have shown that CUR-induced phosphorylated Hog1 migrates to nucleus leading to up-regulation of GPD1 mRNA levels.Back to article page