Table 2 Top 20 differentially regulated genes in gingival tissues according to subgingival levels of A. actinomycetemcomitans, P. gingivalis and C. rectus.
From: Subgingival bacterial colonization profiles correlate with gingival tissue gene expression
Rank | A. actinomycetemcomitans | Â | P. gingivalis | Â | C. rectus | Â |
|---|---|---|---|---|---|---|
| Â | Genea | FCb | Gene | FC | Gene | FC |
1 | hypothetical protein MGC29506 | 5.76 | hypothetical protein MGC29506 | 11.21 | hypothetical protein MGC29506 | 9.04 |
2 | tumor necrosis factor receptor superfamily, member 17 | 4.23 | non-annotated | 8.64 | non-annotated | 7.62 |
3 | sperm associated antigen 4 | 4.01 | tumor necrosis factor receptor superfamily, member 17 | 7.92 | tumor necrosis factor receptor superfamily, member 17 | 6.48 |
4 | interferon, alpha-inducible protein 6 | 3.91 | immunoglobulin kappa variable 1-5 | 7.59 | POU domain, class 2, associating factor 1 | 6.37 |
5 | POU domain, class 2, associating factor 1 | 3.86 | non-annotated | 7.51 | immunoglobulin heavy variable 1-69 | 6.34 |
6 | CD79a molecule, immunoglobulin-associated alpha | 3.65 | immunoglobulin kappa variable 1-5 | 7.42 | sperm associated antigen 4 | 6.14 |
7 | FK506 binding protein 11, 19 kDa | 3.58 | immunoglobulin heavy variable 1-69 | 7.41 | KIAA0125 | 6.10 |
8 | hypothetical protein MGC29506 | 3.56 | interferon, alpha-inducible protein 6 | 7.38 | interferon, alpha-inducible protein 6 | 5.93 |
9 | immunoglobulin lambda locus, immunoglobulin lambda constant 1 | 3.50 | POU domain, class 2, associating factor 1 | 7.18 | immunoglobulin kappa constant, immunoglobulin kappa variable 1-5 | 5.92 |
10 | immunoglobulin heavy constant alpha 1 | 3.47 | immunoglobulin kappa variable 1-5 | 7.16 | interferon, alpha-inducible protein 6 | 5.72 |
11 | KIAA0746 protein | 3.41 | interferon, alpha-inducible protein 6 | 6.97 | immunoglobulin heavy constant alpha 1 | 5.65 |
12 | CD79a molecule, immunoglobulin-associated alpha | 3.39 | non-annotated | 6.96 | Fc receptor-like 5 | 5.60 |
13 | family with sequence similarity 46, member C | 3.34 | immunoglobulin heavy constant alpha 1 | 6.89 | non-annotated | 5.55 |
14 | non-annotated | 3.34 | interferon, alpha-inducible protein 6 | 6.87 | interferon, alpha-inducible protein 6 | 5.53 |
15 | interferon, alpha-inducible protein 6 | 3.26 | Fc receptor-like 5 | 6.85 | interferon, alpha-inducible protein 6 | 5.52 |
16 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 3.20 | KIAA0125 | 6.79 | immunoglobulin lambda locus, immunoglobulin lambda constant 1 (Mcg marker) | 5.49 |
17 | immunoglobulin lambda locus, immunoglobulin lambda constant 1 (Mcg marker) | 3.16 | immunoglobulin kappa variable 1-5 | 6.70 | interferon, alpha-inducible protein 6, immunoglobulin heavy locus (G1m marker) | 5.39 |
18 | KIAA0746 protein | 3.12 | immunoglobulin lambda locus | 6.67 | non-annotated | 5.37 |
19 | SLAM family member 7 | 3.11 | immunoglobulin lambda locus, immunoglobulin lambda constant 1 (Mcg marker) | 6.63 | immunoglobulin lambda locus, immunoglobulin lambda constant 1 (Mcg marker) | 5.36 |
20 | interferon, alpha-inducible protein 6 | 3.03 | sperm associated antigen 4 | 6.59 | immunoglobulin kappa constant, immunoglobulin kappa variable 1-5 | 5.35 |