Figure 4

Effects of A5/L phages on the bone marrow cell composition in cyclophosphamide-treated and S. aureus -infected mice. S – segments, B – bands, Me – metamyelocytes, My – myelocytes, O – other. Mice were given CP (350 mg/kg b.w.). After four days 1 × 10⁶ A5/L phages and 5 × 10⁶ S. aureus were administered. The bone marrow was isolated on day 0, just before administration of CP (Control) and at 24 h following infection (day 5). The results are presented as the mean value of 5 mice per group. Statistics (day 5): Segments: CP^-P^-B⁺ vs CP⁺P^-B⁺ P = 0.0001 (ANOVA; P = 0.0000); Bands: CP^-P^-B⁺ vs CP⁺P^-B⁺ P = 0.0009; CP⁺P^-B⁺ vs CP⁺P⁺B⁺ P = 0.0495 (ANOVA; P = 0.0000); Metamyelocytes: CP^-P^-B⁺ vs CP^-P⁺B⁺ P = 0.0003 (ANOVA; P = 0.0000); Myelocytes: CP⁺P^-B⁺ vs CP⁺P⁺B⁺ P = 0.0062 (ANOVA; P = 0.0000); Other: CP^-P^-B⁺ vs CP⁺P^-B⁺ P = 0.0003 (ANOVA;P = 0.0000). Statistics (day 0 vs day 5): Segments: CP^-P^-B^- vs CP^-P^-B⁺ P = 0.0001; CP^-P^-B^- vs CP^-P⁺B^- P = 0.0000 (ANOVA); Metamyelocytes: CP^-P^-B^- vs CP^-P⁺B⁺ P = 0.0000 (ANOVA); Myelocytes: CP^-P^-B^- vs CP^-P⁺B⁺ P = 0.0016 (ANOVA).