From: Salmonella induces prominent gene expression in the rat colon
Gene Name | Gene symbol | Sequence ID | Fold Change infected vs non-infected rats on different days p.i. | |||
---|---|---|---|---|---|---|
Time course infection studya | Dietary infection studyb | |||||
Day 1 | Day 3 | Day 6 | Day 2 | |||
Transport | ||||||
Ion transport | ||||||
Chloride channel calcium activated 6 | Clca6 | NM_201419 | 2,3 | 2,2 | 3,7 | 2,3 |
Calcium channel, voltage-dependent, alpha 1I subunit | Cacna1i | NM_020084 | 2,2 | 1,5 | - | 1,2 |
Solute carrier family 4, member 1 (Slc4a1), anion exchanger | Slc4a1 | NM_012651 | 2,0 | 1,7 | - | 1,0 |
Atp-ase, H+/K+ transporting, nongastric, alpha polypeptide | Atp12a | NM_133517 | 2,8 | - | 2,0 | 1,1 |
Solute carrier family 20 (phosphate transporter), member 1 | Slc20a1 | NM_031148 | 2,1 | - | - | -1,2 |
Solute carrier family 15 (oligopeptide transporter), member 1 | Slc15a1 | NM_057121 | 2,0 | 1,5 | 1,6 | 0,9 |
Transporter 1, ATP-binding cassette, sub-family B | Mdr/Tap1 | NM_032055 | - | 1,8 | 2,8 | 1,4 |
Oxidative stress | ||||||
Dual oxidase 2 | Duox2 | NM_024141 | 1,9 | 2,4 | 2,8 | 1,6 |
Glutathione peroxidase 2 | Gpx2 | NM_183403 | - | 2,3 | 3,0 | 2,2 |
Xanthine dehydrogenase | Xdh | NM_017154 | - | 1,8 | 2,5 | 1,4 |
Immune response | ||||||
Rat class III Fc-gamma receptor | Fcgr3 | M64368 | 2,1 | 1,6 | - | ND |
Immunoglobulin superfamily, member 4 | Igsf4d | XM_340958 | 2,1 | 1,6 | 1,4 | 1,1 |
Rat MHC class I truncated cell surface antigen | RT1-Aw2 | M10094 | 2,0 | - | 1,9 | 1,0 |
Interleukin enhancer-binding factor 1 | Ilf1 | XM_221212 | 2,0 | 1,5 | - | 1,1 |
Colony stimulating factor 2 (granulocyte-macrophage) | Csf2 | XM_340799 | 2,0 | 1,6 | - | 1,2 |
Interleukin 1 alpha | Il1a | NM_017019 | 1,8 | 2,0 | 2,3 | 1,4 |
Interleukin 1 beta | Il1b | NM_031512 | - | 2,1 | 4,0 | 2,6 |
TRAF2 binding protein | T2bp | NM_001014044 | 1,8 | 2,8 | 4,4 | 2,4 |
Toll-like receptor 2 | Tlr2 | NM_198769 | - | 1,5 | 2,3 | 1,3 |
Antimicrobial defense | ||||||
Lipopolysaccharide binding protein | Lbp | NM_017208 | 1,9 | 1,8 | 2,2 | 1,3 |
Defensin 5 precursor (Enteric defensin) | RD-5 | XM_214386 | -1,9 | -1,6 | -1,6 | ND |
Phospholipase A2, group IIA (platelets, synovial fluid) | Pla2g2a | NM_031598 | 3,4 | 5,2 | 10,5 | 7,3 |
Inflammatory response | ||||||
Pancreatitis-associated protein | Pap | NM_053289 | 11,4 | 44,6 | 114,2 | 17,7 |
Tissue-type transglutaminase | Tgm2 | NM_019386 | - | 2,3 | 4,9 | 1,8 |
Regenerating islet-derived 3 gamma | Reg3g | NM_173097 | - | 2,3 | 4,3 | 1,9 |
Nitric oxide synthase 2, inducible | Nos2 | NM_012611 | - | 1,6 | 4,0 | ND |
S100 calcium binding protein A8 (calgranulin A) | S100a8 | NM_053822 | - | 1,8 | 2,4 | 1,4 |
Calprotectin ⟨ | ||||||
S100 calcium binding protein A9 (calgranulin B) | S100a9 | NM_053587 | - | 1,7 | 1,9 | 1,3 |
Interferon | ||||||
Interferon-induced guanylate-binding protein 1 | Gbp1 | XM_221883 | 2,4 | 1,9 | 2,2 | 1,3 |
Interferon gamma inducible protein | Ifi47 | NM_172019 | 1,7 | 2,7 | 7,3 | 2,6 |
Guanylate binding protein 2, interferon-inducible | Gbp2 | NM_133624 | 1,6 | 2,4 | 3,1 | 1,7 |
Interferon-induced protein | Ifit2 | NM_001024753 | 1,5 | 1,7 | 3,4 | 1,3 |
Interferon-stimulated protein | G1P2 | XM_216605 | - | 1,6 | 4,1 | 1,5 |
Immunity-related GTPase family, M | Irgm | NM_001012007 | - | 1,8 | 3,7 | 1,4 |
Signal transducer and activator of transcription 1 | Stat1 | NM_032612 | - | 1,7 | 3,6 | 1,8 |
Interferon regulatory factor 7 | Irf7 | XM_215121 | - | 1,5 | 2,6 | ND |
Alpha-interferon | Ifna | XM_233145 | - | 2,0 | - | ND |
Proteolysis | ||||||
Ubiquitin D | Ubd | NM_053299 | 1,7 | 2,5 | 15,2 | 3,4 |
Proteosome (prosome, macropain) subunit, beta type 9 | Psmb9 | NM_012708 | - | 2,0 | 3,7 | 2,0 |
Protease, serine, 22 | Prss22 | XM_220222 | - | 2,0 | 2,6 | 1,6 |
Potential ubiquitin ligase | Herc6 | XM_342700 | - | 1,7 | 3,3 | 1,5 |
Proteasome (prosome, macropain) subunit, beta type 10 | Psmb10 | XM_214687 | - | 1,5 | 2,1 | 1,5 |