Figure 3
From: Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis
Alignment of selected family III aminotransferases. The following sequences were aligned with the Clustal algorithm: Mt-BCAT, M. tuberculosis BCAT [23]; Mb-BCAT, M. bovis BCAT [51]; Mm-BCAT, M. marinum BCAT; Mu-BCAT, M. ulcerans BCAT; Ml-BCAT, M. leprae BCAT [52]; Ma-BCAT, M. avium BCAT; Ms- BCAT, M. smegmatis BCAT; Sc- BCAT, Streptomyces coelicolor BCAT [53]; Bs-BCAT, Bacillus subtilis BCAT YbgE [43]; Hs-BCAT1, human BCAT1 [54]; Ec-BCAT, Escherichia coli BCAT IlvE [55]; Ba-BCAT, B. anthracis BCAT2 [16]; Bs-DAAT, B. subtilis DAAT YheM [43]). Residues conserved by 80% of the sequences are shown in blue. The boxed residues represent the pyridoxal-5-phosphate binding site.