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Table 5 Spa -types and groups in which deletions/insertions in the spa -gene were observed

From: Prevalence of Staphylococcus aureus protein A (spa) mutants in the community and hospitals in Oxfordshire

Spa-types

Spa-repeats

Individuals with deletions, no. (column %)

Hidden deletions not affecting spa-typing (no.)

Deletions/insertions affecting spa-typing (no.)

Individuals with deletions affecting spa-typing/total individuals with this spa-type

  Group 1

 

7 (21%)

  

7/20 (35%)*

t571

08-16-02-25-02-25-----------34-25

6 (18%)

 

delG-insB(5); delE(1)

6/19 (32%)

t3085

08-16-02-25-02-25-34-25-34-25

1 (3%)

 

delE (1)

1/1 (100%)

  Group 2

 

9 (27%)

  

7/188 (4%)*

t021

15-12------16-02-16---------------02-25-17-24--------------

4 (12%)

delD(1)

insC2(3)

3/57 (5%)

t298

15-12------16-02-----------------------------17-24--------------

1 (3%)

 

delG-insB (1)

1/5 (20%)

t10173

15-12-02-16-02------25-17-25-02-25-17-24-24---------

1 (3%)

 

insC2 (1)

1/1 (100%)

t012

15-12------16-02-16---------------02-25-17-24-24---------

2 (6%)

 

delE (1); insC2 (1)

2/123 (2%)

t6803

15-12------16-02-16---------------02-25-17-24-24-17-24

1 (3%)

delD-insA (1)

 

0/2 (0%)

  Group 3

 

3 (9%)

  

-

t084

07-23-12-34-34-12-12-23-02-12-23

1 (3%)

delH (1)

 

-

t085

07-23-12-34-34-12-----23-02-12-23

2 (6%)

delD (1); delA (1)

 

-

  Group 4

 

4 (12%)

  

3/74 (4%)*

t280

04--------------------20-17-12-12-17-------------

1 (3%)

 

delG-insB (1)

1/4 (25%)

t227

04-----------------------------12-12-17-------------

1 (3%)

delD (1)

 

0/3 (0%)

t078

04-21a-12b-41c-20-17-12-12-17-------------

1 (3%)

 

delE (1)

1/26 (4%)

t216

04----------20-17-20-17------------31d-16e-34f

1 (3%)

 

delG-insB (1)

1/41 (2%)

  Group 5

 

3 (9%)

  

1/92 (1%)*

t032

26-23-23-13-23-31-29-17-31-29-17-25-17-25-16-28

2 (6%)

delD (1)

delE (1)

1/79 (1%)

t223

26-23-----13-23-------------------05g-17-25-17-25-16-28

1 (3%)

delD (1)

 

0/13 (0%)

Singletons

 

7 (21%)

  

-

t213

07-23-12-21-24-33-22-17

3 (9%)

delD (3)

 

-

t6792

08-16-02-16-17-13-17-13-17-16-34

1 (3%)

delD (1)

 

-

t6417

14-44-13-12-17-13-12-17-17-17-23-18

1 (3%)

dell (1)

 

-

t530

11-19-12-21-17-34-24-34-16

1 (3%)

 

delE (1)

1/3 (33%)*

t7960

299-25-17-17-16-16-16-16

1 (3%)

delI-insC1 (1)

 

-

Total

 

33 (100%)

   
  1. * P < 0.0001 comparing four groups of spa-types and the singleton with rearrangements affecting spa-typing (5 × 2 Fisher’s exact test).
  2. 21a repeat differing in one base from repeats 12 and 20.
  3. 12b repeat differing in two bases from repeats 20.
  4. 41c repeat differing in one base from repeat 17.
  5. 31d repeat differing in two bases from repeat 16.
  6. 16e repeat differing in one base from repeat 17.
  7. 34f repeat differing in two bases from repeats 12 and 20.
  8. 05g repeat differing in one base from repeat 29.
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BMC Microbiology

ISSN: 1471-2180

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