Figure 4
LTB 4 and PGE 2 production by alveolar macrophages is differentially induced by PLC-expressing Mycobacterium tuberculosis . Cells were infected with Mtb isolates 97-1200 or 97-1505 for 2, 12, 24, and 48 hours and the eicosanoid production was assessed in the supernatants by ELISA. ***P < 0.0001; **P < 0.001 (one-way ANOVA). Data are representative of three (A) and two (B) independent experiments (error bars, s.e.m.).