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Table 3 IL-1β secretion from F. tularensis-infected BMDM cells

From: The Francisella tularensis LVS ΔpdpCmutant exhibits a unique phenotype during intracellular infection

Strain

IL-1β secretion (pg/ml)a

 

5 h

24 h

-

BDL***

BDL***

LVS

76.3 ± 10.9

497.1 ± 79.0

ΔiglC

39.6b

BDL***

ΔpdpC

64.5 ± 27.2

112.1 ± 41.0*

ΔpdpC/pdpC

163.2 ± 50.2

506.9 ± 94.3

  1. aF. tularensis-infected, or uninfected (-) BMDM cells were incubated for 5 or 24 h. The average IL-1β secretion in pg/ml with standard errors of triplicate biological samples from one representative experiment, out of three, is shown. A Student’s t-test was used to determine if the IL-1β secretion was significantly different between LVS infected and mutant infected cells (*: P < 0.05, **: P < 0.01, ***: P < 0.001). BDL means that the concentration was below the detection limit of the assay (< 31.25 pg/ml).
  2. b Only one of the triplicates was above BDL.
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BMC Microbiology

ISSN: 1471-2180

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