From: Protein level identification of the Listeria monocytogenes Sigma H, Sigma L, and Sigma C regulons
Proteina | Fold change Δ BCH/ΔBCHL | Description | Gene name | Role categoryb | Sub-Role categoryb |
---|---|---|---|---|---|
Proteins with positive fold change ( > 1.5) and p < 0.05 (indicating positive regulation by σL) | |||||
Lmo0096d,f | 64.16 | mannose-specific PTS system IIAB component ManL | mptA | Energy metabolism | Pyruvate dehydrogenase |
Amino acid biosynthesis | Aromatic amino acid family | ||||
Transport and binding proteins | Carbohydrates, organic alcohols, and acids | ||||
Lmo2006g | 3.41 | acetolactate synthase catabolic | alsS | Amino acid biosynthesis | Aspartate family |
Amino acid biosynthesis | Pyruvate family | ||||
Proteins with negative fold change ( < -1.5) and p < 0.05 (indicating negative regulation by σL) | |||||
Lmo0027c,e | −3.62 | beta-glucoside-specific PTS system IIABC component | lmo0027 | Transport and binding proteins | Carbohydrates, organic alcohols, and acids |
Amino acid biosynthesis | Aromatic amino acid family | ||||
Energy metabolism | Pyruvate dehydrogenase | ||||
Lmo0130 | −3.64 | hypothetical protein | lmo0130 | Unclassified | Role category not yet assigned |
Lmo0178 | −2.07 | hypothetical protein | lmo0178 | Regulatory functions | Other |
Lmo0181 | −3.25 | multiple sugar transport system substrate-binding protein | lmo0181 | Transport and binding proteins | Unknown substrate |
Lmo0260 | −1.68 | hydrolase | lmo0260 | Hypothetical proteins | Conserved |
Lmo0278 | −1.67 | maltose/maltodextrin transport system ATP-binding protein | lmo0278 | Transport and binding proteins | Carbohydrates, organic alcohols, and acids |
Lmo0319c,e | −2.96 | beta-glucosidase | bglA | Energy metabolism | Sugars |
Lmo0343 | −3.94 | transaldolase | tal2 | Energy metabolism | Pentose phosphate pathway |
Lmo0344 | −4.69 | short chain dehydrogenase | lmo0344 | Energy metabolism | Biosynthesis and degradation of polysaccharides |
Lmo0345 | −6.04 | ribose 5-phosphate isomerase B | lmo0345 | Energy metabolism | Pentose phosphate pathway |
Lmo0346 | −2.74 | triosephosphate isomerase | tpiA2 | Energy metabolism | Glycolysis/gluconeogenesis |
Lmo0348 | −2.41 | dihydroxyacetone kinase | lmo0348 | Fatty acid and phospholipid metabolism | Biosynthesis |
Energy metabolism | Sugars | ||||
Lmo0391 | −1.67 | hypothetical protein | lmo0391 | ||
Lmo0401 | −2.16 | alpha-mannosidase | lmo0401 | Unclassified | Role category not yet assigned |
Lmo0517e | −3.21 | phosphoglycerate mutase | lmo0517 | Energy metabolism | Glycolysis/gluconeogenesis |
Lmo0521 | −2.23 | 6-phospho-beta-glucosidase | lmo0521 | Energy metabolism | Sugars |
Lmo0536 | −1.97 | 6-phospho-beta-glucosidase | lmo0536 | Central intermediary metabolism | Other |
Lmo0574 | −1.65 | 6-phospho-beta-glucosidase GmuD | lmo0574 | Central intermediary metabolism | Other |
Lmo0640 | −1.78 | oxidoreductase | lmo0640 | Energy metabolism | Fermentation |
Central intermediary metabolism | Other | ||||
Energy metabolism | Electron transport | ||||
Lmo0643 | −2.61 | transaldolase | lmo0643 | Energy metabolism | Pentose phosphate pathway |
Lmo0689 | −1.71 | chemotaxis protein CheV | lmo0689 | Cellular processes | Chemotaxis and motility |
Lmo0690 | −2.44 | flagellin | flaA | Cellular processes | Chemotaxis and motility |
Lmo0692 | −1.66 | chemotaxis protein CheA | cheA | Cellular processes | Chemotaxis and motility |
Lmo0813 | −2.04 | fructokinase | lmo0813 | Energy metabolism | Sugars |
Lmo0930 | −1.88 | hypothetical protein | lmo0930 | Unclassified | Role category not yet assigned |
Lmo1242 | −1.59 | hypothetical protein | lmo1242 | Hypothetical proteins | Conserved |
Lmo1254 | −2.10 | alpha-phosphotrehalase | lmo1254 | Energy metabolism | Biosynthesis and degradation of polysaccharides |
Lmo1348 | −2.42 | glycine cleavage system T protein | gcvT | Energy metabolism | Amino acids and amines |
Lmo1349 | −2.68 | glycine cleavage system P-protein | gcvPA | Energy metabolism | Amino acids and amines |
Central intermediary metabolism | Other | ||||
Lmo1350e | −2.11 | glycine dehydrogenase subunit 2 | gcvPB | Central intermediary metabolism | Other |
Energy metabolism | Amino acids and amines | ||||
Lmo1388e | −2.02 | ABC transport system | tcsA | Unclassified | Role category not yet assigned |
Lmo1389 | −2.32 | simple sugar transport system ATP-binding protein | lmo1389 | Transport and binding proteins | Carbohydrates, organic alcohols, and acids |
Lmo1538e | −1.89 | glycerol kinase | glpK | Energy metabolism | Other |
Lmo1699 | −1.92 | Methyl-accepting chemotaxis protein | lmo1699 | Cellular processes | Chemotaxis and motility |
Lmo1730 | −2.55 | lactose/L-arabinose transport system substrate-binding protein | lmo1730 | Transport and binding proteins | Carbohydrates, organic alcohols, and acids |
Lmo1791 | −1.75 | hypothetical protein | lmo1791 | ||
Lmo1812 | −1.70 | L-serine dehydratase iron-sulfur-dependent alpha subunit | lmo1812 | Energy metabolism | Amino acids and amines |
Energy metabolism | Glycolysis/gluconeogenesis | ||||
Lmo1856 | −1.65 | purine nucleoside phosphorylase | deoD | Purines, pyrimidines, nucleosides, and nucleotides | Salvage of nucleosides and nucleotides |
Lmo1860 | −1.64 | peptide-methionine (S)-S-oxide reductase | msrA | Protein fate | Protein modification and repair |
Lmo1877 | −2.14 | formate-tetrahydrofolate ligase | fhs | Amino acid biosynthesis | Aspartate family |
Protein synthesis | tRNA aminoacylation | ||||
Amino acid biosynthesis | Histidine family | ||||
Purines, pyrimidines, nucleosides, and nucleotides | Purine ribonucleotide biosynthesis | ||||
Biosynthesis of cofactors, prosthetic groups, and carriers | Pantothenate and coenzyme A | ||||
Lmo1954e | −1.97 | phosphopentomutase | deoB | Purines, pyrimidines, nucleosides, and nucleotides | Salvage of nucleosides and nucleotides |
Lmo1993 | −1.81 | pyrimidine-nucleoside phosphorylase | pdp | Purines, pyrimidines, nucleosides, and nucleotides | Salvage of nucleosides and nucleotides |
Lmo2094 | −28.99 | hypothetical protein | lmo2094 | Energy metabolism | Sugars |
Lmo2097 | −12.12 | galactitol-specific PTS system IIB component | lmo2097 | Energy metabolism | Pyruvate dehydrogenase |
Amino acid biosynthesis | Aromatic amino acid family | ||||
Transport and binding proteins | Carbohydrates, organic alcohols, and acids | ||||
Lmo2098 | −3.96 | galactitol-specific PTS system IIA component | lmo2098 | Energy metabolism | Pyruvate dehydrogenase |
Amino acid biosynthesis | Aromatic amino acid family | ||||
Transport and binding proteins | Carbohydrates, organic alcohols, and acids | ||||
Lmo2160 | −2.37 | sugar phosphate isomerase/epimerase | lmo2160 | Hypothetical proteins | Conserved |
Lmo2161 | −2.58 | hypothetical protein | lmo2161 | Hypothetical proteins | Conserved |
Lmo2362 | −1.87 | glutamate/gamma-aminobutyrate antiporter | lmo2362 | Transport and binding proteins | Amino acids, peptides and amines |
Lmo2425 | −1.59 | glycine cleavage system H protein | gcvH | Energy metabolism | Amino acids and amines |
Lmo2481 | −1.52 | pyrophosphatase PpaX | ppaX | Central intermediary metabolism | Other |
Lmo2529 | −1.72 | ATP synthase F1 beta subunit | atpD2 | Energy metabolism | ATP-proton motive force interconversion |
Lmo2648 | −2.50 | hypothetical protein | lmo2648 | Unclassified | Role category not yet assigned |
Lmo2664 | −1.72 | L-iditol 2-dehydrogenase | lmo2664 | Central intermediary metabolism | Other |
Energy metabolism | Glycolysis/gluconeogenesis | ||||
Energy metabolism | Electron transport | ||||
Energy metabolism | TCA cycle | ||||
Energy metabolism | Fermentation | ||||
Lmo2696 | −2.68 | dihydroxyacetone kinase L subunit | lmo2696 | Energy metabolism | Sugars |
Fatty acid and phospholipid metabolism | Biosynthesis | ||||
Lmo2697 | −3.10 | dihydroxyacetone kinase | lmo2697 | Hypothetical proteins | Conserved |
Lmo2743 | −2.71 | transaldolase | tal1 | Energy metabolism | Pentose phosphate pathway |