Table 1 COG category of differentially-expressed genes in NCTC 11168 in response to treatment with an inhibitory dose of Ery
From: Adaptive mechanisms of Campylobacter jejunito erythromycin treatment
COG category | No. up-regulated (%)* | No. down-regulated (%)* | Total No. differentially expressed genes |
|---|---|---|---|
Amino acid transport and metabolism | 14 (11.11%) | 12 (9.52%) | 26 |
Carbohydrate transport and metabolism | 1 (2.94%) | 4 (11.76%) | 5 |
Cell cycle control, mitosis and meiosis | 2 (14.29%) | 2 (14.29%) | 4 |
Cell motility | 10 (19.23%) | 2 (3.85%) | 12 |
Cell wall/membrane biogenesis | 3 (2.52%) | 9 (7.56%) | 12 |
Coenzyme transport and metabolism | 7 (10.14%) | 3 (4.35%) | 10 |
Defense mechanisms | 2 (8.70%) | 0 (0.00%) | 2 |
Energy production and conversion | 6 (6.32%) | 30 (31.58%) | 36 |
Function unknown | 9 (12.67%) | 3 (4.23%) | 12 |
General function prediction only | 12 (8.45%) | 10 (7.04%) | 22 |
Intracellular trafficking and secretion | 0 (0.00%) | 1 (2.17%) | 1 |
Inorganic ion transport and metabolism | 9 (11.11%) | 4 (4.94%) | 13 |
Lipid transport and metabolism | 3 (8.57%) | 0 (0.00%) | 3 |
Nucleotide transport and metabolism | 1 (2.33%) | 4 (9.30%) | 5 |
Poorly characterized | 32 (6.00%) | 19 (3.56%) | 51 |
Posttranslational modification, chaperones | 6 (9.23%) | 7 (10.77%) | 13 |
Replication, recombination and repair | 3 (5.00%) | 3 (5.00%) | 6 |
Signal transduction mechanisms | 3 (6.67%) | 1 (2.22%) | 4 |
Transcription | 6 (13.95%) | 1 (2.33%) | 7 |
Translation | 10 (10.00%) | 4 (4.00%) | 14 |
Total | 139 | 119 | 258 |