Correlation of intestinal microbiota with overweight and obesity in Kazakh school children

BMC Microbiology

Table 2 Subjects’ demographics, characteristics and microbe microbiota data by group

Variables	Total	Normal group	Overweight group	Obesity group	P-values
	(n = 175)	(n = 91)	(n = 62)	(n = 22)
Age (y)	9.87 ± 1.97	9.92 ± 1.98	9.65 ± 1.87	10.32 ± 2.19	0.368
Sex					0.906
Boys	87 (49.7)	45 (49.5)	30 (48.4)	12 (54.5)
Girls	88 (50.3)	46 (50.5)	32 (51.6)	10 (45.5)
BMI, Kg/m²	18.87 ± 3.45	16.53 ± 1.69	20.14 ± 1.83^†	24.94 ± 3.11^†‡	<0.001^*
SBP, mmHg	97.66 ± 14.93	94.06 ± 12.68	98.34 ± 13.21	110.64 ± 20.45^†‡	<0.001^*
DBP, mmHg	62.16 ± 9.15	60.38 ± 8.1	63.07 ± 9.15	66.93 ± 11.39^†	0.005^*
Waist, cm	63 ± 8.7	58.27 ± 4.91	65.08 ± 6.75^†	76.72 ± 9.22^†‡	<0.001^*
Hip, cm	74.48 ± 9.98	70.26 ± 6.65	76.04 ± 8.7^†	87.52 ± 12.41^†‡	<0.001^*
FPG, mmol/L	4.81 ± 0.84	4.88 ± 1.03	4.73 ± 0.57	4.8 ± 0.61	0.569
Triglyceride, mmol/L	1.21 ± 0.53	1.14 ± 0.47	1.27 ± 0.58	1.36 ± 0.55	0.194
Cholesterol, mmol/L	3.67 ± 0.71	3.73 ± 0.71	3.65 ± 0.68	3.52 ± 0.81	0.424
HDL, mmol/L	1.38 ± 0.51	1.35 ± 0.48	1.38 ± 0.56	1.53 ± 0.46	0.206
LDL, mmol/L	1.58 ± 0.43	1.57 ± 0.45	1.58 ± 0.37	1.62 ± 0.48	0.885
Insulin, mmol/L	6.55 ± 3.74	6.1 ± 3.47	6.21 ± 3.28	9.29 ± 4.86^‡	0.006^*
HOMA-IR	1.42 ± 0.87	1.34 ± 0.83	1.33 ± 0.76	1.99 ± 1.14^†‡	0.016^*
Bacteroidetes × 10⁷copies/μL	1.31 ± 1.94	1.5 ± 2.2	1.37 ± 1.77	0.33 ± 0.47^†	0.002^*
Firmicutes × 10⁷copies/μL	2.58 ± 4.52	2.43 ± 4.53	2.05 ± 3.01	4.7 ± 7.01	0.628
Bact/Firm	0.98 ± 0.71	1.06 ± 0.62	1.03 ± 0.82	0.48 ± 0.52^†‡	<0.001^*

(N = 175).
Data were presented as mean ± SD for continuous data and n(%) for categorical data.
Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL, high density lipoprotein; LDL, low density lipoprotein; Bact/Firm, ratio of Bacteroidetes to Firmicutes.
^*P < 0.05, indicated significant differences among groups.
^†,‡P < 0.0167, indicated significant differences as compared with the ^†normal and ^‡overweight groups.

ISSN: 1471-2180