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Table 2 Association between number of CagA EPIYA C motifs and H. pylori-associated diseases

From: Higher number of Helicobacter pylori CagA EPIYA C phosphorylation sites increases the risk of gastric cancer, but not duodenal ulcer

 

Univariate analysis

Multivariate analysis

 

p

OR

95% CI

p

Gastric cancer

    

   - Increasing age

< 10-3

1.04

1.03 - 1.06

< 10-3

   - Female sex

< 10-3

0.29

0.18 - 0.48

< 10-3

   - High-risk EPIYA (ABCC or ABCCC)

< 10-3

3.08

1.74 - 5.45

< 10-3

Duodenal ulcer

    

   - Increasing age

< 10-3

1.03

1.02 - 1.05

< 10-3

   - Female sex

0.04

1.26

0.73 - 2.18

0.41

   - High-risk EPIYA (ABCC or ABCCC)

0.29

-

-

-

  1. The Hosmer-Lemeshow test showed good fitness of the model of gastric cancer (8 degrees of freedom, p = 0.86, with 10 steps) and duodenal ulcer (8 degrees of freedom, p = 0.25, with 10 steps).
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BMC Microbiology

ISSN: 1471-2180

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