Table 2 Previously published interactions among lambda proteins

1

A

Nu1

A (N-term) - Nu1 (C-term)

[32–34]

2

A

B

A (C-term) - B (= portal)

[32, 35]

3

A

FI

Genetic evidence

[21]

4

FI

E

Genetic evidence

[22]

5

Nu3

B

Nu3 required for B incorporation into procapsid

[36]

6

W

B

[37, 38]

7

W

FII

W required for FII binding, FII connects head to tail

[37, 39]

8

B

B

12-mer (22 aa removed from B N-term)

[40, 41]

9

C

E

Covalent PPI (in virion?)

[42, 43]

10

C

B

[44]

11

B

E

copurify in procapsid

[45]

12

C

Nu3

C may degrade Nu3 (before DNA packaging)

[45–47]

13

D

D

Capsid vertices, D forms trimers

[48–50]

14

E

E

Main capsid protein

[20, 51, 52]

15

D

E

[20, 51, 52]

Nu3

Nu3

Nu3 multimer

unpublished *

16

U

U

"probably a hexamer", interact in crystal

[53]

17

V

V

[51, 54–56]

18

V

GT

the T domain binds soluble V

[24]

19

H

G/GT

G/GT hold H in an extended fashion

[24]

20

H

V

V probably assembles around H, displacing G/GT

[57]

21

O

O

O-O interactions when bound to ori DNA

[58]

22

O

P

[59–62]

23

CI

CI

Forms octamer that links O_R to O_L

[63, 64]

24

CII

CII

homotetramers

[65]

25

CIII

CIII

dimer

[66]

26

Cro

Cro

dimer; x-ray structure

[67]

27

Exo

Bet

[68]

28

Xis

Int

[69] #

29

Xis

Xis

Xis-Xis binding mediates cooperative DNA-binding

[69] #

30

Int

Int

Dimer

[70]

31

Rz

Rz1

heteromultimer that is supposed to span the periplasm

[71]

32

S

S

large ring in inner membrane

[72]

S

S'

S' inhibits S ring formation (S: 105 aa, S': 107 aa)

[73]

33

SieB

Esc

Esc is encoded in frame in sieB + inhbits sieB

[74, 75] #