Figure 8
Genes diverged between East Asian and European strains. (A) Diagram of phylogenetic tree-based analysis. Black dots, last common ancestors of Eastern and Western strains. d a , length of the branch separating the two; d b , average branch length of the Eastern strains. (B) Plot of gene trees based on the two distance values. Large green dot, well-defined core tree; d a *, d a for the well-defined core tree; d b *, d b for the well-defined core tree; inset box, well-defined core tree; zone 1, d b < 0.00550; zone 2, 0.00550 ≤ d b ≤ 0.0231; zone 3, d b > 0.0231; red dot, genes with positive selection for amino acid change and with d a > 2 × d a *, that is, d a >0.02324; (a), cheY; (b), fixQ; (c), sotA; (d), vacA; (e), cagA; (f), HP1250. N = 692 genes. (C) Representative trees with high divergence between hspEAsia and hpEurope strains. Lowest common ancestor (LCA) of hspEAsia (red) and hpEurope (cyan).