Figure 2
From: Binding and activation of host plasminogen on the surface of Francisella tularensis
Purified huPLG binds to FTLVS and FTSchuS4. FTLVS (Panel A) and FTSchuS4 (Panel B) were bound to microtiter wells and incubated for 2 hours with purified huPLG (3 μg/ml) in the presence or absence of 10 mM εACA). A modified ELISA was performed to measure FTLVS-bound huPLG. The results shown are representative of four (Panel A) and one (Panel B) experiments, respectively, of similar design. Bars indicate +/- SEM in triplicate. Statistical analysis was performed via one-way ANOVA using a Dunnett's Multiple Comparison post-test (*** P < .001).