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Table 1 Effect on MBC values of various antimicrobial agents

From: An enhancer peptide for membrane-disrupting antimicrobial peptides

 

MBC (μg/mL)

 

NP4P-a

NP4P+

ASABF-αb

  

   Staphylococcus aureus IFO12732

3

0.3

   Micrococcus luteus IFO12708

5

2

   Bacillus subtilis IFO3134

8

3

   Escherichia coli JM109

3

0.3

   Pseudomonas aeruginosa IFO3899

5

2

   Salmonella typhimurium IFO13245

3

2

   Serratia marcescens IFO3736

3

1.5

Polymyxin Bb

  

   Escherichia coli JM109

3

0.3

   Pseudomonas aeruginosa IFO3899

5

2.5

   Salmonella typhimurium IFO13245

5

2.5

   Serratia marcescens IFO3736

5

1

Nisinb

  

   Staphylococcus aureus IFO12732

5

2

Indolicidinc

  

   Staphylococcus aureus IFO12732

10

10

   Escherichia coli JM109

10

10

Ampicillinc

  

   Staphylococcus aureus IFO12732

250

250

Kanamycinc

  

   Staphylococcus aureus IFO12732

3

3

Enrofloxacinc

  

   Staphylococcus aureus IFO12732

0.25

0.25

  1. a Each MBC value was determined in the presence or absence of 20 μg/mL NP4P.
  2. b Membrane disruptive.
  3. c Not membrane disruptive.
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BMC Microbiology

ISSN: 1471-2180

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