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Table 2 Transcript level of the sodA, sodM genes in Staphylococcus aureus clinical isolates.

From: Superoxide dismutase is upregulated in Staphylococcus aureus following protoporphyrin-mediated photodynamic inactivation and does not directly influence the response to photodynamic treatment

S. aureus strain

Strain response to PDI

Sod genes transcript level [copies/μl]1

Sod genes transcript level [copies/μl]2

Transcript level increase [× fold]

  

Before PDI 3

After PDI 3

Before PDI 3

After PDI 3

 
  

SodA

472

sensitive

372150

396674

418.1

5666.7

13.5

80/0

sensitive

1671

3136

2.5

52.2

20

1397

resistant

450267

24647

662.1

68.4

0.1

4246

resistant

4978943

1482683

3387.0

2745.7

0.8

  

SodM

472

sensitive

59205

194245

66.5

2774.9

41

80/0

sensitive

56789

21804

87.3

363.4

4.1

1397

resistant

123025

45475

279.6

119.6

0.4

4246

resistant

286623

198523

267.8

208.9

0.8

  1. 1 - absolute number of amplified mRNA fragment
  2. 2 - values normalized with respect to the number of c.f.u. (colony forming units)
  3. 3 - PDI - Photodynamic inactivation performed with 50 μM protoporphyrin IX, light dose of 12 J/cm2, 624 nm red light.