Table 1 Genes expressed differentially in strain 1457ΔlytSR compared to the wild-type strain

Amino acid biosynthesis

SERP0034

metE

5-methyltetrahydropteroyltriglutamate homocysteine methyltransferase

2.096

SERP0108

gltB

glutamate synthase large subunit

2.405

SERP0548

argH

argininosuccinate lyase

5.03

SERP1103

aroK

shikimate kinase

2.274

SERP1668

ilvC

ketol-acid reductoisomerase

2.087

SERP1669

leuA

2-isopropylmalate synthase

2.344

SERP1670

leuB

3-isopropylmalate dehydrogenase

2.229

SERP1671

leuC

3-isopropylmalate dehydratase small subunit

11.45

SERP2301

hisF

imidazoleglycerol phosphate synthase, cyclase subunit

5.429

Amino acid transport

SERP0392

di-tripeptide transporter, putative

3.362

SERP0571

oppC

oligopeptide transport system permease protein OppC

12.38

SERP0950

peptide ABC transporter, ATP-binding protein, putative

3.383

SERP1440

putP

proline permease

2.124

SERP1935

gltS

sodium:glutamate symporter

3.267

Inorganic ion transport and metabolism

SERP0284

Na+/H+ antiporter, MnhD component, putative

3.294

SERP0287

Na+/H+ antiporter, MnhG component, putative

2.576

SERP0660

cobalt transport family protein

2.718

SERP1777

iron compound ABC transporter, iron

2.383

SERP1859

modC

molybdenum transport ATP-binding protein

3.294

SERP2428

arsA

arsenical pump-driving ATPase

3.274

Protein synthesis

SERP0721

pheS

Phe-tRNA synthetase alpha chain

2.036

SERP1809

infA

translation initiation factor IF-1

0.5

SERP1812

rplO

ribosomal protein L15

0.482

SERP1813

rpmD

ribosomal protein L30

0.333

SERP1814

rpsE

30 S ribosomal protein S5

0.37

SERP1815

rplR

50 S ribosomal protein L18

0.323

SERP1816

rplF

50 S ribosomal protein L6

0.332

SERP1817

rpsH

30 S ribosomal protein S8

0.357

SERP1818

rpsN-2

30 S ribosomal protein S14

0.306

SERP1819

rplE

50 S ribosomal protein L5

0.324

SERP1821

rplN

50 S ribosomal protein L14

0.346

SERP1820

rplX

50 S ribosomal protein L24

0.356

SERP1822

rpsQ

30 S ribosomal protein S17

0.344

SERP1823

rpmC

50 S ribosomal protein L29

0.332

SERP1824

rplP

50 S ribosomal protein L16

0.438

SERP1825

rpsC

30 S ribosomal protein S3

0.345

SERP1826

rplV

50 S ribosomal protein L22

0.374

SERP1827

rpsS

30 S ribosomal protein S19

0.385

SERP1828

rplB

50 S ribosomal protein L2

0.421

SERP1829

rplW

50 S ribosomal protein L23

0.424

Nucleotide metabolism

SERP0070

guaA

bifunctional GMP synthase/glutamine amidotransferase protein

2.546

SERP0651

purC

phosphoribosylaminoimidazole-succinocarboxamide synthase

2.036

SERP0654

purL

phosphoribosylformylglycinamidine synthetase

2.341

SERP0655

purF

phosphoribosylpyrophosphate amidotransferase

2.164

SERP0656

purM

phosphoribosylformylglycinamidine cyclo-ligase

2.369

SERP0657

purN

IMP cyclohydrolase

2.111

SERP1003

thyA-1

thymidylate synthase

2.014

SERP1810

adk

adenylate kinase

0.444

Energy metabolism

SE0102-12228

carbamate kinase, putative

0.259

SE0104-12228

transcription regulator Crp/Fnr family protein

0.343

SE0106-12228

arcA

arginine deiminase

0.301

SERP0672

cydA

cytochrome d ubiquinol oxidase subunit II-like protein

13.85

SERP1985

narJ

nitrate reductase delta chain

0.441

SERP1986

narH

nitrate reductase beta chain

0.327

SERP1987

narG

nitrate reductase alpha chain

0.324

SERP1990

nirB

nitrite reductase nitrite reductase

0.354

SERP2168

mqo-2

malate:quinone oxidoreductase

0.317

SERP2169

hypothetical protein

0.0165

SERP2261

manA-2

mannose-6-phosphate isomerase

0.479

SERP2312

mqo-3

malate:quinone oxidoreductase

0.451

SERP2352

arcC

putative carbamate kinase

0.427

DNA replication, recombination and repair

SERP0558

ISSep1-like transposase

4.66

SERP0599

site-specific recombinase, resolvase family

2.352

SERP0892

IS1272, transposase

2.774

SERP0909

lexA

SOS regulatory LexA protein

2.227

SERP1023

DNA replication protein DnaD, putative

2.049

SERP2474

hsdR

type I restriction-modification system, R subunit

46.79

Transcriptional regulator

SERP0635

transcriptional regulator, MarR family

3.216

SERP1879

transcriptional regulator, AraC family

21.2