Figure 4From: In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosisAt the early stage of pulmonary colonisation, neutrophil influx limits fungal germination after clodrolip treatment. (A): Multifocal inflammatory lesion centred on bronchi/bronchioles and blood vessels (arrowheads). (B): Inflammatory cells observed in alveolar spaces (arrowheads). (C, E): Inflammatory infiltrates containing fragmented neutrophils (suppuration, white stars). (D, F): In the inflammatory infiltrates (black star) only non-germinated conidia (arrowheads) were observed. A, B, C, E: HE staining; D, F: GMS staining.Back to article page