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Figure 4 | BMC Microbiology

Figure 4

From: In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

Figure 4

At the early stage of pulmonary colonisation, neutrophil influx limits fungal germination after clodrolip treatment. (A): Multifocal inflammatory lesion centred on bronchi/bronchioles and blood vessels (arrowheads). (B): Inflammatory cells observed in alveolar spaces (arrowheads). (C, E): Inflammatory infiltrates containing fragmented neutrophils (suppuration, white stars). (D, F): In the inflammatory infiltrates (black star) only non-germinated conidia (arrowheads) were observed. A, B, C, E: HE staining; D, F: GMS staining.

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