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Figure 13 | BMC Microbiology

Figure 13

From: In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

Figure 13

In the late stage after cyclophosphamide treatment no inflammatory response was observed and A. fumigatus rapidly colonised the pulmonary parenchyma. (A): Diffuse lesion characterised by a total absence of inflammatory response with a severe destruction of the bronchoalveolar structures (black star: bronchiole; white star: pulmonary artery). (B): Severe parenchyma colonisation by the fungus with infiltration of bronchioles (black star) as well as pulmonary arteries (white star). (C): Destruction of the bronchiolar (black star), alveolar, and vascular (white star) walls by hyphae. (D): Branched mature hyphae were observed, displaying a high infiltrative potential. A, C: HE staining; B, D: GMS staining.

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BMC Microbiology

ISSN: 1471-2180

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