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  1. Staphylococcus epidermidis has emerged as one of the most important nosocomial pathogens, mainly because of its ability to colonize implanted biomaterials by forming a biofilm. Extensive studies are focused on th...

    Authors: Tao Zhu, Qiang Lou, Yang Wu, Jian Hu, Fangyou Yu and Di Qu
    Citation: BMC Microbiology 2010 10:287
    Content type: Research article Published on:

  2. Although non-typeable (NT) Haemophilus influenzae and Haemophilus haemolyticus are closely related human commensals, H. haemolyticus is non-pathogenic while NT H. influenzae is an important cause of respiratory t...

    Authors: Kirk W McCrea, Jingping Xie, Carl F Marrs and Janet R Gilsdorf
    Citation: BMC Microbiology 2010 10:286
    Content type: Research article Published on:

  3. Accurate identification is necessary to discriminate harmless environmental Yersinia species from the food-borne pathogens Yersinia enterocolitica and Yersinia pseudotuberculosis and from the group A bioterrorism...

    Authors: Saravanan Ayyadurai, Christophe Flaudrops, Didier Raoult and Michel Drancourt
    Citation: BMC Microbiology 2010 10:285
    Content type: Methodology article Published on:

  4. Rhizobium leguminosarum bv. trifolii is a symbiotic nitrogen-fixing bacterium that elicits nodules on roots of host plants Trifolium spp. Bacterial surface polysaccharides are crucial for establishment of a succe...

    Authors: Monika Janczarek, Jolanta Kutkowska, Tomasz Piersiak and Anna Skorupska
    Citation: BMC Microbiology 2010 10:284
    Content type: Research article Published on:

  5. Phenotypic heterogeneity may ensure that a small fraction of a population survives environmental perturbations or may result in lysis in a subpopulation, to increase the survival of siblings. Genes involved in...

    Authors: Simona Kamenšek, Zdravko Podlesek, Osnat Gillor and Darja Žgur-Bertok
    Citation: BMC Microbiology 2010 10:283
    Content type: Research article Published on:

  6. Pseudomonas aeruginosa is commonly associated with contact lens (CL) -related eye infections, for which bacterial adhesion and biofilm formation upon hydrogel CLs is a specific risk factor. Whilst P. aeruginosa h...

    Authors: Claudia Rändler, Rutger Matthes, Andrew J McBain, Bernd Giese, Martin Fraunholz, Rabea Sietmann, Thomas Kohlmann, Nils-Olaf Hübner and Axel Kramer
    Citation: BMC Microbiology 2010 10:282
    Content type: Methodology article Published on:

  7. Rhodocista centenaria is a phototrophic α-proteobacterium exhibiting a phototactic behaviour visible as colony movement on agar plates directed to red light. As many phototrophic purple bacteria R. centenaria pos...

    Authors: Sven Kreutel, Andreas Kuhn and Dorothee Kiefer
    Citation: BMC Microbiology 2010 10:281
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Microbiology 2017 17:186

  8. Glyceraldehyde 3-phosphate dehydrogenases (GAPDHs) are cytoplasmic glycolytic enzymes, which although lacking identifiable secretion signals, have also been found localized to the surface of several bacteria (...

    Authors: Sarfraz A Tunio, Neil J Oldfield, Dlawer AA Ala'Aldeen, Karl G Wooldridge and David PJ Turner
    Citation: BMC Microbiology 2010 10:280
    Content type: Research article Published on:

  9. Acinetobacter baumannii is a multidrug-resistant bacterium responsible for nosocomial infections in hospitals worldwide. Study of mutant phenotypes is fundamental for understanding gene function. The methodologie...

    Authors: Jesús Aranda, Margarita Poza, Belén G Pardo, Soraya Rumbo, Carlos Rumbo, José R Parreira, Patricia Rodríguez-Velo and Germán Bou
    Citation: BMC Microbiology 2010 10:279
    Content type: Methodology article Published on:

  11. In our previous studies on lipoprotein secretion in the Lyme disease spirochete Borrelia burgdorferi, we used monomeric red fluorescent protein 1 (mRFP1) fused to specifically mutated outer surface protein A (Osp...

    Authors: Ozan S Kumru, Ryan J Schulze, Joyce G Slusser and Wolfram R Zückert
    Citation: BMC Microbiology 2010 10:277
    Content type: Methodology article Published on:

  12. LuxS is the synthase enzyme of the quorum sensing signal AI-2. In Salmonella Typhimurium, it was previously shown that a luxS deletion mutant is impaired in biofilm formation. However, this phenotype could not be...

    Authors: Gwendoline Kint, David De Coster, Kathleen Marchal, Jos Vanderleyden and Sigrid CJ De Keersmaecker
    Citation: BMC Microbiology 2010 10:276
    Content type: Research article Published on:

  13. We infected freshly isolated human peripheral monocytes with live bacteria of three clinically important gram-positive bacterial species, Staphylococcus aureus, Streptococcus pneumoniae and Listeria monocytogenes

    Authors: Svetlin Tchatalbachev, Rohit Ghai, Hamid Hossain and Trinad Chakraborty
    Citation: BMC Microbiology 2010 10:275
    Content type: Research article Published on:

  14. Pandemic Vibrio parahaemolyticus has undergone rapid changes in both K- and O-antigens, making detection of outbreaks more difficult. In order to understand these rapid changes, the genetic regions encoding these...

    Authors: Yuansha Chen, Jianli Dai, J Glenn Morris Jr and Judith A Johnson
    Citation: BMC Microbiology 2010 10:274
    Content type: Research article Published on:

  16. Rhomboids are ubiquitous proteins with diverse functions in all life kingdoms, and are emerging as important factors in the biology of some pathogenic apicomplexa and Providencia stuartii. Although prokaryotic ge...

    Authors: David P Kateete, Moses Okee, Fred A Katabazi, Alfred Okeng, Jeniffer Asiimwe, Henry W Boom, Kathleen D Eisenach and Moses L Joloba
    Citation: BMC Microbiology 2010 10:272
    Content type: Research article Published on:

  17. Ferredoxins are small iron-sulfur proteins belonging to all domains of life. A sub-group binds two [4Fe-4S] clusters with unequal and extremely low values of the reduction potentials. These unusual properties ...

    Authors: Sylvie Elsen, Georgios Efthymiou, Panagiotis Peteinatos, George Diallinas, Panayotis Kyritsis and Jean-Marc Moulis
    Citation: BMC Microbiology 2010 10:271
    Content type: Research article Published on:

  18. Arcanobacterium haemolyticum is an emerging bacterial pathogen, causing pharyngitis and more invasive infections. This organism expresses an unusual phospholipase D (PLD), which we propose promotes bacterial path...

    Authors: Erynn A Lucas, Stephen J Billington, Petteri Carlson, David J McGee and B Helen Jost
    Citation: BMC Microbiology 2010 10:270
    Content type: Research article Published on:

  19. A commercial biotyping system (Taxa Profileâ„¢, Merlin Diagnostika) testing the metabolization of various substrates by bacteria was used to determine if a set of phenotypic features will allow the identificatio...

    Authors: Sascha Al Dahouk, Holger C Scholz, Herbert Tomaso, Peter Bahn, Cornelia Göllner, Wolfram Karges, Bernd Appel, Andreas Hensel, Heinrich Neubauer and Karsten Nöckler
    Citation: BMC Microbiology 2010 10:269
    Content type: Research article Published on:

  20. Two genotypically and microbiologically distinct strains of Mycobacterium avium subsp. paratuberculosis (MAP) exist - S and C MAP strains that primarily infect sheep and cattle, respectively. Concentration of iro...

    Authors: Harish K Janagama, Senthilkumar, John P Bannantine, Abirami Kugadas, Pratik Jagtap, LeeAnn Higgins, Bruce A Witthuhn and Srinand Sreevatsan
    Citation: BMC Microbiology 2010 10:268
    Content type: Research article Published on:

  21. Clostridium botulinum, an obligate anaerobic spore-forming bacterium, produces seven antigenic variants of botulinum toxin that are distinguished serologically and termed "serotypes". Botulinum toxin blocks the r...

    Authors: Brenna J Hill, Janet C Skerry, Theresa J Smith, Stephen S Arnon and Daniel C Douek
    Citation: BMC Microbiology 2010 10:267
    Content type: Methodology article Published on:

  22. Intravascular catheter related infection (CRI) is one of the most serious nosocomial infections. Diagnostic criteria include a positive culture from the catheter tip along with blood, yet in many patients with...

    Authors: Li Zhang, Kadaba S Sriprakash, David McMillan, John R Gowardman, Bharat Patel and Claire M Rickard
    Citation: BMC Microbiology 2010 10:266
    Content type: Research article Published on:

  24. It is well established in E. coli and Vibrio cholerae that strains harboring mutations in the ferric uptake regulator gene (fur) are unable to utilize tricarboxylic acid (TCA) compounds, due to the down-regulatio...

    Authors: Yunfeng Yang, Lee Ann McCue, Andrea B Parsons, Sheng Feng and Jizhong Zhou
    Citation: BMC Microbiology 2010 10:264
    Content type: Research article Published on:

  25. Typhoid, which is caused by Salmonella enterica serovar Typhimurium, remains a major health concern worldwide. Multidrug-resistant strains of Salmonella have emerged which exhibit increased survivability and viru...

    Authors: Jun Sik Lee, In Duk Jung, Chang-Min Lee, Jin Wook Park, Sung Hak Chun, Soo Kyung Jeong, Tae kwun Ha, Yong Kyoo Shin, Dae Jin Kim and Yeong-Min Park
    Citation: BMC Microbiology 2010 10:263
    Content type: Research article Published on:

  26. Terminal-Restriction Fragment Length Polymorphism (T-RFLP) is a technique used to analyze complex microbial communities. It allows for the quantification of unique or numerically dominant phylotypes in amplico...

    Authors: Antonio Fernàndez-Guerra, Alison Buchan, Xiaozhen Mou, Emilio O Casamayor and José M González
    Citation: BMC Microbiology 2010 10:262
    Content type: Software Published on:

  28. In recent years, there has been an increasing interest in SSBs because they find numerous applications in diverse molecular biology and analytical methods.

    Authors: Marcin Olszewski, Anna Grot, Marek Wojciechowski, Marta Nowak, Małgorzata Mickiewicz and Józef Kur
    Citation: BMC Microbiology 2010 10:260
    Content type: Research article Published on:

  29. The three trypanosomatids pathogenic to men, Trypanosoma cruzi, Trypanosoma brucei and Leishmania major, are etiological agents of Chagas disease, African sleeping sickness and cutaneous leishmaniasis, respective...

    Authors: Michel Batista, Fabricio K Marchini, Paola AF Celedon, Stenio P Fragoso, Christian M Probst, Henrique Preti, Luiz S Ozaki, Gregory A Buck, Samuel Goldenberg and Marco A Krieger
    Citation: BMC Microbiology 2010 10:259
    Content type: Methodology article Published on:

  30. The increasing availability of whole genome sequences allows the gene or protein content of different organisms to be compared, leading to burgeoning interest in the relatively new subfield of pan-genomics. Ho...

    Authors: Brett Trost, Monique Haakensen, Vanessa Pittet, Barry Ziola and Anthony Kusalik
    Citation: BMC Microbiology 2010 10:258
    Content type: Research article Published on:

  31. Corynebacterium diphtheriae, the causative agent of diphtheria, is well-investigated in respect to toxin production, while little is known about C. diphtheriae factors crucial for colonization of the host. In thi...

    Authors: Lisa Ott, Martina Höller, Johannes Rheinlaender, Tilman E Schäffer, Michael Hensel and Andreas Burkovski
    Citation: BMC Microbiology 2010 10:257
    Content type: Research article Published on:

  32. Osmosensing and associated signal transduction pathways have not yet been described in obligately halophilic bacteria. Chromohalobacter salexigens is a halophilic bacterium with a broad range of salt tolerance. I...

    Authors: Javier Rodríguez-Moya, Montserrat Argandoña, Mercedes Reina-Bueno, Joaquín J Nieto, Fernando Iglesias-Guerra, Mohamed Jebbar and Carmen Vargas
    Citation: BMC Microbiology 2010 10:256
    Content type: Research article Published on:

  33. The primer and amplicon length have been found to affect PCR based estimates of microbial diversity by pyrosequencing, while other PCR conditions have not been addressed using any deep sequencing method. The p...

    Authors: Jin-Ya Wu, Xiao-Tao Jiang, Yun-Xia Jiang, Su-Ying Lu, Fei Zou and Hong-Wei Zhou
    Citation: BMC Microbiology 2010 10:255
    Content type: Methodology article Published on:

  34. Medium chain length (mcl-) polyhydroxyalkanoates (PHA) are synthesized by many bacteria in the cytoplasm as storage compounds for energy and carbon. The key enzymes for PHA metabolism are PHA polymerase (PhaC)...

    Authors: Qun Ren, Guy de Roo, Bernard Witholt, Manfred Zinn and Linda Thöny-Meyer
    Citation: BMC Microbiology 2010 10:254
    Content type: Research article Published on:

  35. Pre-elafin/trappin-2 is a human innate defense molecule initially described as a potent inhibitor of neutrophil elastase. The full-length protein as well as the N-terminal "cementoin" and C-terminal "elafin" d...

    Authors: Audrey Bellemare, Nathalie Vernoux, Sébastien Morin, Stéphane M Gagné and Yves Bourbonnais
    Citation: BMC Microbiology 2010 10:253
    Content type: Research article Published on:

  36. The Gram negative anaerobic bacterium Porphyromonas gingivalis has long been recognized as a causative agent of periodontitis. Periodontitis is a chronic infectious disease of the tooth supporting tissues eventua...

    Authors: Jorg Brunner, Floyd RA Wittink, Martijs J Jonker, Mark de Jong, Timo M Breit, Marja L Laine, Johannes J de Soet and Wim Crielaard
    Citation: BMC Microbiology 2010 10:252
    Content type: Research article Published on:

  38. Burkholderia pseudomallei and Burkholderia mallei cause the diseases melioidosis and glanders, respectively. A well-studied aspect of pathogenesis by these closely-related bacteria is their ability to invade and ...

    Authors: Rachel Balder, Serena Lipski, John J Lazarus, William Grose, Ronald M Wooten, Robert J Hogan, Donald E Woods and Eric R Lafontaine
    Citation: BMC Microbiology 2010 10:250
    Content type: Research article Published on:

  39. Salmonella Enteritidis is a highly prevalent and persistent foodborne pathogen and is therefore a leading cause of nontyphoidal gastrointestinal disease worldwide. A variety of stresses are endured throughout its...

    Authors: Leona N Calhoun, Rohana Liyanage, Jackson O Lay Jr and Young Min Kwon
    Citation: BMC Microbiology 2010 10:249
    Content type: Research article Published on:

  40. When heterologous recombinant proteins are produced in Escherichia coli, they often precipitate to form insoluble aggregates of unfolded polypeptides called inclusion bodies. These structures are associated with ...

    Authors: Charles Van der Henst, Caroline Charlier, Michaël Deghelt, Johan Wouters, Jean-Yves Matroule, Jean-Jacques Letesson and Xavier De Bolle
    Citation: BMC Microbiology 2010 10:248
    Content type: Research article Published on:

  41. Bordetella dermonecrotic toxin (DNT) causes the turbinate atrophy in swine atrophic rhinitis, caused by a Bordetella bronchiseptica infection of pigs, by inhibiting osteoblastic differentiation. The toxin is not ...

    Authors: Aya Fukui-Miyazaki, Shigeki Kamitani, Masami Miyake and Yasuhiko Horiguchi
    Citation: BMC Microbiology 2010 10:247
    Content type: Research article Published on:

  42. Several mutations have been described as responsible for rifampicin resistance in Neisseria meningitidis. However, the intriguing question on why these strains are so rare remains open. The aim of this study was ...

    Authors: Arianna Neri, Giuseppina Mignogna, Cecilia Fazio, Alessandra Giorgi, Maria Eugenia Schininà and Paola Stefanelli
    Citation: BMC Microbiology 2010 10:246
    Content type: Research article Published on:

  43. Pseudomonas aeruginosa is the major respiratory pathogen causing severe lung infections among CF patients, leading to high morbidity and mortality. Once infection is established, early antibiotic treatment is abl...

    Authors: Pieter Deschaght, Petra Schelstraete, Guido Lopes dos Santos Santiago, Leen Van Simaey, Filomeen Haerynck, Sabine Van daele, Elke De Wachter, Anne Malfroot, Patrick Lebecque, Christiane Knoop, Georges Casimir, Hedwige Boboli, Frédéric Pierart, Kristine Desager, Mario Vaneechoutte and Frans De Baets
    Citation: BMC Microbiology 2010 10:245
    Content type: Research article Published on:

  44. Coxiella burnetii is an intracellular bacterial pathogen that causes acute and chronic disease in humans. Bacterial replication occurs within enlarged parasitophorous vacuoles (PV) of eukaryotic cells, the biogen...

    Authors: Saugata Mahapatra, Patricia Ayoubi and Edward I Shaw
    Citation: BMC Microbiology 2010 10:244
    Content type: Research article Published on:

  45. Anthracnose, caused by Colletotrichum dematium, is a serious threat to the production and quality of mulberry leaves in susceptible varieties. Control of the disease has been a major problem in mulberry cultivati...

    Authors: Xianling Ji, Guobing Lu, Yingping Gai, Huijv Gao, Baoyun Lu, Lingrang Kong and Zhimei Mu
    Citation: BMC Microbiology 2010 10:243
    Content type: Research article Published on:

  46. The two-component systems of Mycobacterium tuberculosis are apparently required for its growth and resistance in hostile host environments. In such environments, MtrAB has been reported to regulate the expression...

    Authors: Yuqing Li, Jumei Zeng, Hua Zhang and Zheng-Guo He
    Citation: BMC Microbiology 2010 10:242
    Content type: Research article Published on:

  47. Phospholipase B (PLB) has been reported to be one of the virulence factors for human pathogenic fungi and has also been described as necessary for the early events in infection. Based on these data, we investi...

    Authors: Deyze Alencar Soares, Rosângela Vieira de Andrade, Simoneide Sousa Silva, Anamélia Lorenzetti Bocca, Sueli Maria Soares Felipe and Silvana Petrofeza
    Citation: BMC Microbiology 2010 10:241
    Content type: Research article Published on:

  48. The transport and catabolism of sialic acid, a critical virulence factor for nontypeable Haemophilus influenzae, is regulated by two transcription factors, SiaR and CRP.

    Authors: Jason W Johnston, Haider Shamsulddin, Anne-Frances Miller and Michael A Apicella
    Citation: BMC Microbiology 2010 10:240
    Content type: Research article Published on:

  49. Bacterial penicillin-binding proteins (PBPs) can be visualized by their ability to bind radiolabeled or fluorescent β-lactam derivatives both whole cells and membrane/cell enriched fractions. Analysis of the List...

    Authors: Dorota Korsak, Zdzislaw Markiewicz, Gabriel O Gutkind and Juan A Ayala
    Citation: BMC Microbiology 2010 10:239
    Content type: Research article Published on:

  50. GUP1 gene was primarily identified in Saccharomyces cerevisiae being connected with glycerol uptake defects in association with osmotic stress response. Soon after, Gup1p was implicated in a complex and extensive...

    Authors: Célia Ferreira, Sónia Silva, Fábio Faria-Oliveira, Eva Pinho, Mariana Henriques and Cândida Lucas
    Citation: BMC Microbiology 2010 10:238
    Content type: Research article Published on:
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