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  1. The capsular polysaccharide (CPS) and iron acquisition systems are important determinants of Klebsiella pneumoniae infections, and we have previously reported that the ferric uptake repressor (Fur) can play dual ...

    Authors: Su-Hua Huang, Chien-Kuo Wang, Hwei-Ling Peng, Chien-Chen Wu, Ying-Tsong Chen, Yi-Ming Hong and Ching-Ting Lin
    Citation: BMC Microbiology 2012 12:148
  2. Plague is caused by Yersinia pestis, a bacterium that disseminates inside of the host at remarkably high rates. Plague bacilli disrupt normal immune responses in the host allowing for systematic spread that is fa...

    Authors: Rodrigo J Gonzalez, Eric H Weening, Richard Frothingham, Gregory D Sempowski and Virginia L Miller
    Citation: BMC Microbiology 2012 12:147
  3. Methicillin-resistant Staphylococcus aureus (MRSA) is spreading worldwide and poses a serious public health problem, being present in hospital settings and communities. However, from the Middle East and the Arabi...

    Authors: Stefan Monecke, Leila Skakni, Rami Hasan, Antje Ruppelt, Sameeh S Ghazal, Ahmed Hakawi, Peter Slickers and Ralf Ehricht
    Citation: BMC Microbiology 2012 12:146
  4. Treatment of cystic fibrosis-associated lung infections is hampered by the presence of multi-drug resistant pathogens, many of which are also strong biofilm producers. Antimicrobial peptides, essential compone...

    Authors: Arianna Pompilio, Valentina Crocetta, Marco Scocchi, Stefano Pomponio, Valentina Di Vincenzo, Mario Mardirossian, Giovanni Gherardi, Ersilia Fiscarelli, Giordano Dicuonzo, Renato Gennaro and Giovanni Di Bonaventura
    Citation: BMC Microbiology 2012 12:145
  5. Bacterial infections have been linked to malignancies due to their ability to induce chronic inflammation. We investigated the association of oral bacteria in oral squamous cell carcinoma (OSCC/tumor) tissues ...

    Authors: Smruti Pushalkar, Xiaojie Ji, Yihong Li, Cherry Estilo, Ramanathan Yegnanarayana, Bhuvanesh Singh, Xin Li and Deepak Saxena
    Citation: BMC Microbiology 2012 12:144
  6. Avian pathogenic Escherichia coli (APEC) and uropathogenic E. coli (UPEC) are the two main subsets of extraintestinal pathogenic E. coli (ExPEC). Both types have multiple iron acquisition systems, including heme ...

    Authors: Qingqing Gao, Xiaobo Wang, Huiqing Xu, Yaya Xu, Jielu Ling, Debao Zhang, Song Gao and Xiufan Liu
    Citation: BMC Microbiology 2012 12:143
  7. Ruminal disbiosis induced by feeding is the cause of ruminal acidosis, a digestive disorder prevalent in high-producing ruminants. Because probiotic microorganisms can modulate the gastrointestinal microbiota,...

    Authors: Abderzak Lettat, Pierre Nozière, Mathieu Silberberg, Diego P Morgavi, Claudette Berger and Cécile Martin
    Citation: BMC Microbiology 2012 12:142
  8. Hazelnut (Corylus avellana) decline disease in Greece and Italy is caused by the convergent evolution of two distantly related lineages of Pseudomonas syringae pv. avellanae (Pav). We sequenced the genomes of thr...

    Authors: Heath E O’Brien, Shalabh Thakur, Yunchen Gong, Pauline Fung, Jianfeng Zhang, Lijie Yuan, Pauline W Wang, Choseung Yong, Marco Scortichini and David S Guttman
    Citation: BMC Microbiology 2012 12:141
  9. Klebsiella pneumoniae can be found in environmental habitats as well as in hospital settings where it is commonly associated with nosocomial infections. One of the factors that contribute to virulence is its capa...

    Authors: Diana P Cruz, Mónica G Huertas, Marcela Lozano, Lina Zárate and María Mercedes Zambrano
    Citation: BMC Microbiology 2012 12:139
  10. Mycoplasma gallisepticum is a major poultry pathogen and causes severe economic loss to the poultry industry. In mycoplasmas lipoproteins are abundant on the membrane surface and play a critical role in interacti...

    Authors: Indu S Panicker, Anna Kanci, Chien-Ju Chiu, Paul D Veith, Michelle D Glew, Glenn F Browning and Philip F Markham
    Citation: BMC Microbiology 2012 12:138
  11. Mycobacteria can be quickly and simply identified by PCR restriction-enzyme analysis (PRA), but misidentification can occur because of similarities in band sizes that are critical for discriminating among spec...

    Authors: Chen-Cheng Huang, Jiann-Hwa Chen, Shiau-Ting Hu, Chien-Shun Chiou, Wei-Chang Huang, Jeng-Yuan Hsu, Jang-Jih Lu and Gwan-Han Shen
    Citation: BMC Microbiology 2012 12:137
  12. PII proteins have a fundamental role in the control of nitrogen metabolism in bacteria, through interactions with different PII targets, controlled by metabolite binding and post-translational modification, ur...

    Authors: Pedro Filipe Teixeira, Maria A Dominguez-Martin and Stefan Nordlund
    Citation: BMC Microbiology 2012 12:136
  13. Enterococci are among the leading causes of hospital-acquired infections in the United States and Europe, with Enterococcus faecalis and Enterococcus faecium being the two most common species isolated from entero...

    Authors: Xiang Qin, Jessica R Galloway-Peña, Jouko Sillanpaa, Jung Hyeob Roh, Sreedhar R Nallapareddy, Shahreen Chowdhury, Agathe Bourgogne, Tina Choudhury, Donna M Muzny, Christian J Buhay, Yan Ding, Shannon Dugan-Rocha, Wen Liu, Christie Kovar, Erica Sodergren, Sarah Highlander…
    Citation: BMC Microbiology 2012 12:135
  14. When grown under anaerobic conditions, Escherichia coli K-12 is able to synthesize three active [NiFe]-hydrogenases (Hyd1-3). Two of these hydrogenases are respiratory enzymes catalysing hydrogen oxidation, where...

    Authors: Constanze Pinske, Monique Jaroschinsky, Frank Sargent and Gary Sawers
    Citation: BMC Microbiology 2012 12:134
  15. The parasitic nematode Spirocerca lupi (Spirurida: Thelaziidae), the canine esophageal worm, is the causative agent of spirocercosis, a disease causing morbidity and mortality in dogs. Spirocerca lupi has a compl...

    Authors: Yuval Gottlieb, Eran Lavy, Meira Kaufman, Alex Markovics, Murad Ghanim and Itamar Aroch
    Citation: BMC Microbiology 2012 12:133
  16. Dietary rice bran consists of many bioactive components with disease fighting properties; including the capacity to modulate the gut microbiota. Studies point to the important roles of the gut microbiota and t...

    Authors: Ajay Kumar, Angela Henderson, Genevieve M Forster, Andrew W Goodyear, Tiffany L Weir, Jan E Leach, Steven W Dow and Elizabeth P Ryan
    Citation: BMC Microbiology 2012 12:71
  17. It has been well established that the Gα subunit of the heterotrimeric G-protein in the wheat pathogen Stagonospora nodorum is required for a variety of phenotypes including pathogenicity, melanisation and asexua...

    Authors: Joel P A Gummer, Robert D Trengove, Richard P Oliver and Peter S Solomon
    Citation: BMC Microbiology 2012 12:131
  18. Clostridium difficile is the main cause of antibiotic associated diarrhea. In the past decade, the number of C. difficile patients has increased dramatically, coinciding with the emergence of two PCR ribotypes 02...

    Authors: Jeroen Corver, Dennis Bakker, Michael S M Brouwer, Céline Harmanus, Marjolein P Hensgens, Adam P Roberts, Len J A Lipman, Ed J Kuijper and Hans C van Leeuwen
    Citation: BMC Microbiology 2012 12:130
  19. Chronic gastritis, peptic ulcer disease, and gastric cancer have been shown to be related to infection with Helicobacter pylori (H. pylori). Two major virulence factors of H. pylori, CagA and VacA, have been asso...

    Authors: Anneli Karlsson, Anna Ryberg, Marjan Nosouhi Dehnoei, Kurt Borch and Hans-Jürg Monstein
    Citation: BMC Microbiology 2012 12:129
  20. Chemotaxis is crucial for the colonisation/infection of hosts with Campylobacter jejuni. Central to chemotaxis are the group A chemotaxis genes that are responsible for sensing the external environment. The distr...

    Authors: Christopher J Day, Lauren E Hartley-Tassell, Lucy K Shewell, Rebecca M King, Greg Tram, Serena K Day, Evgeny A Semchenko and Victoria Korolik
    Citation: BMC Microbiology 2012 12:128
  21. Bacteriophages have the destructive damage on the industrial bioprocess. 2-Keto-gluconic acid (2KGA) producing bacteria had also been attacked and lysed by bacteriophages which lowered the glucose consumption ...

    Authors: Wen-Jing Sun, Chang-Feng Liu, Lin Yu, Feng-Jie Cui, Qiang Zhou, Si-Lian Yu and Lei Sun
    Citation: BMC Microbiology 2012 12:127
  22. The white-rot fungus Phanerochaete chrysosporium is among the small group of fungi that can degrade lignin to carbon dioxide while leaving the crystalline cellulose untouched. The efficient lignin oxidation syste...

    Authors: Dong-Dong Yang, Jean Marie François and Gustavo M de Billerbeck
    Citation: BMC Microbiology 2012 12:126
  23. Anandamide (Arachidonoyl ethanolamide) is a potent bioactive lipid studied extensively in humans, which regulates several neurobehavioral processes including pain, feeding and memory. Bioactivity is terminated...

    Authors: Dhamodharan Neelamegan, Ian C Schoenhofen, James C Richards and Andrew D Cox
    Citation: BMC Microbiology 2012 12:124
  24. Dietary supplementation with zinc has been shown to reduce the duration and severity of diarrhoeal disease caused by Enteropathogenic Escherichia coli, common in infants in developing countries. Initially this th...

    Authors: Jay L Mellies, Katherine Thomas, Michael Turvey, Neil R Evans, John Crane, Ed Boedeker and Gregory C Benison
    Citation: BMC Microbiology 2012 12:123
  25. Concrete corrosion of wastewater collection systems is a significant cause of deterioration and premature collapse. Failure to adequately address the deteriorating infrastructure networks threatens our environ...

    Authors: Vicente Gomez-Alvarez, Randy P Revetta and Jorge W Santo Domingo
    Citation: BMC Microbiology 2012 12:122
  26. Microbial anaerobic digestion (AD) is used as a waste treatment process to degrade complex organic compounds into methane. The archaeal and bacterial taxa involved in AD are well known, whereas composition of ...

    Authors: Jarmo Ritari, Kaisa Koskinen, Jenni Hultman, Jukka M Kurola, Maritta Kymäläinen, Martin Romantschuk, Lars Paulin and Petri Auvinen
    Citation: BMC Microbiology 2012 12:121
  27. Uropathogenic strains of Escherichia coli cause symptomatic infections whereas asymptomatic bacteriuria (ABU) strains are well adapted for growth in the human urinary tract, where they establish long-term bacteri...

    Authors: Cecile Aubron, Jeremy Glodt, Corine Matar, Olivier Huet, Didier Borderie, Ulrich Dobrindt, Jacques Duranteau, Erick Denamur, Marc Conti and Odile Bouvet
    Citation: BMC Microbiology 2012 12:120
  28. Listeria monocytogenes can cause invasive diseases in humans and farm animals and is frequently isolated from dairy products and poultry. Listeriosis is uncommon in China but L. monocytogenes has been isolated fr...

    Authors: Yan Wang, Ailan Zhao, Renfa Zhu, Ruiting Lan, Dong Jin, Zhigang Cui, Yonglu Wang, Zhenchuan Li, Yiting Wang, Jianguo Xu and Changyun Ye
    Citation: BMC Microbiology 2012 12:119
  29. Glycopeptidolipids (GPLs) are among the major free glycolipid components of the outer membrane of several saprophytic and clinically-relevant Mycobacterium species. The architecture of GPLs is based on a constant...

    Authors: Elizabeth Tatham, Sivagami sundaram Chavadi, Poornima Mohandas, Uthamaphani R Edupuganti, Shiva K Angala, Delphi Chatterjee and Luis E N Quadri
    Citation: BMC Microbiology 2012 12:118
  30. Burkholderia pseudomallei and Burkholderia mallei are gram-negative pathogens responsible for the diseases melioidosis and glanders, respectively. Both species cause disease in humans and animals and have been de...

    Authors: Nathan A Fisher, Wilson J Ribot, Willard Applefeld and David DeShazer
    Citation: BMC Microbiology 2012 12:117
  31. Plant root exudates have been shown to play an important role in mediating interactions between plant growth-promoting rhizobacteria (PGPR) and their host plants. Most investigations were performed on Gram-neg...

    Authors: Ben Fan, Lilia C Carvalhais, Anke Becker, Dmitri Fedoseyenko, Nicolaus von Wirén and Rainer Borriss
    Citation: BMC Microbiology 2012 12:116
  32. The sequenced O45:K1:H7 Escherichia coli meningitis strain S88 harbors a large virulence plasmid. To identify possible genetic determinants of pS88 virulence, we examined the transcriptomes of 88 plasmidic ORFs c...

    Authors: Chloé Lemaître, Philippe Bidet, Edouard Bingen and Stéphane Bonacorsi
    Citation: BMC Microbiology 2012 12:115
  33. The production of Streptococcus pyogenes exoproteins, many of which contribute to virulence, is regulated in response to nutrient availability. CodY is a transcriptional regulator that controls gene expression in...

    Authors: Emily J McDowell, Eduardo A Callegari, Horst Malke and Michael S Chaussee
    Citation: BMC Microbiology 2012 12:114
  34. The routinely used microbiological diagnosis of ventilator associated pneumonia (VAP) is time consuming and often requires invasive methods for collection of human specimens (e.g. bronchoscopy). Therefore, it ...

    Authors: Wojciech Filipiak, Andreas Sponring, Maria Magdalena Baur, Anna Filipiak, Clemens Ager, Helmut Wiesenhofer, Markus Nagl, Jakob Troppmair and Anton Amann
    Citation: BMC Microbiology 2012 12:113
  35. A major outbreak of bloody diarrhea associated with Shiga toxin-producing Escherichia coli O104:H4 occurred early in 2011, to which an unusual number of hemolytic uremic syndrome cases were linked. Due to limited...

    Authors: Alfredo G Torres, Roberto J Cieza, Maricarmen Rojas-Lopez, Carla A Blumentritt, Cristiane S Souza, R Katie Johnston, Nancy Strockbine, James B Kaper, Elena Sbrana and Vsevolod L Popov
    Citation: BMC Microbiology 2012 12:112
  36. Salmonella enterica serotype Typhimurium produces surface-associated fimbriae that facilitate adherence of the bacteria to a variety of cells and tissues. Type 1 fimbriae with binding specificity to mannose resid...

    Authors: Ke-Chuan Wang, Yuan-Hsun Hsu, Yi-Ning Huang and Kuang-Sheng Yeh
    Citation: BMC Microbiology 2012 12:111
  37. Brucellosis is a worldwide disease of mammals caused by Alphaproteobacteria in the genus Brucella. The genus is genetically monomorphic, requiring extensive genotyping to differentiate isolates. We utilized two d...

    Authors: Jeffrey T Foster, Lance B Price, Stephen M Beckstrom-Sternberg, Talima Pearson, William D Brown, Danika M Kiesling, Christina A Allen, Cindy M Liu, James Beckstrom-Sternberg, Frank F Roberto and Paul Keim
    Citation: BMC Microbiology 2012 12:110
  38. The pbr resistance operon from Cupriavidus metallidurans CH34 plasmid pMOL30 confers resistance to Pb(II) salts, and is regulated by the Pb(II) responsive regulator PbrR, which is a MerR family activator. In othe...

    Authors: Jon L Hobman, Daniel J Julian and Nigel L Brown
    Citation: BMC Microbiology 2012 12:109
  39. Haemophilus parasuis is the causative agent of Glässer’s disease and is a pathogen of swine in high-health status herds. Reports on serotyping of field strains from outbreaks describe that approximately 30% of th...

    Authors: Emilie S Zehr, Dennis V Lavrov and Louisa B Tabatabai
    Citation: BMC Microbiology 2012 12:108
  40. Deoxyhypusine synthase (DHS) catalyzes the first step in hypusine biosynthesis of eukaryotic initiation factor 5A (eIF-5A) in Plasmodium falciparum. Target evaluation of parasitic DHS has recently been performed ...

    Authors: Andreas Schwentke, Marcel Krepstakies, Ann-Kristin Mueller, Christiane Hammerschmidt-Kamper, Basma A Motaal, Tina Bernhard, Joachim Hauber and Annette Kaiser
    Citation: BMC Microbiology 2012 12:107
  41. Aflatoxins (AFs) are highly carcinogenic compounds produced by Aspergillus species in seeds with high lipid and protein contents. It has been known for over 30 years that peptone is not conducive for AF productio...

    Authors: Shijuan Yan, Yating Liang, Jindan Zhang and Chun-Ming Liu
    Citation: BMC Microbiology 2012 12:106
  42. Inflammatory bowel diseases are associated with increased expression of zinc-dependent Matrix Metalloproteinase 9 (MMP-9). A stark dysregulation of intestinal mucosal homeostasis has been observed in patients ...

    Authors: David M Rodrigues, Andrew J Sousa, Steve P Hawley, Linda Vong, Melanie G Gareau, Sachin A Kumar, Kathene C Johnson-Henry and Philip M Sherman
    Citation: BMC Microbiology 2012 12:105
  43. In this study, we present evidence that proteins encoded by the Locus of Enterocyte Effacement (LEE), considered critical for Escherichia coli O157 (O157) adherence to follicle-associated epithelial (FAE) cells a...

    Authors: Indira T Kudva, Robert W Griffin, Bryan Krastins, David A Sarracino, Stephen B Calderwood and Manohar John
    Citation: BMC Microbiology 2012 12:103
  44. Microbes are extensively associated with insects, playing key roles in insect defense, nutrition and reproduction. Most of the associations reported involve Proteobacteria. Despite the fact that Actinobacteria as...

    Authors: Tiago D Zucchi, Simone S Prado and Fernando L Cônsoli
    Citation: BMC Microbiology 2012 12:101
  45. Clostridium butyricum has become increasingly important in preventing and treating intestinal inflammation. In the intestine it may increase the resistance of the gut to pathogen invasion via inducing the secreti...

    Authors: Quanxin Gao, Lili Qi, Tianxing Wu and Jinbo Wang
    Citation: BMC Microbiology 2012 12:100

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