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  1. Lamivudine is an oral nucleoside analogue widely used for the treatment of chronic hepatitis B. The main limitation of lamivudine use is the selection of resistant mutations that increases with time of utiliza...

    Authors: Marcelle Bottecchia, Francisco JD Souto, Kycia MR Ó, Marcia Amendola, Carlos E Brandão, Christian Niel and Selma A Gomes
    Citation: BMC Microbiology 2008 8:11
  2. The administration of non-antifungal drugs during patient hospitalization might be responsible for discrepancies between in vitro and in vivo susceptibility to antifungals. Propofol is often administered to inten...

    Authors: Sofia Costa-de-Oliveira, Ricardo Araujo, Ana Silva-Dias, Cidália Pina-Vaz and Acácio Gonçalves Rodrigues
    Citation: BMC Microbiology 2008 8:9
  3. The response regulator DegU and its cognate histidine kinase DegS constitute a two-component system in the Gram-positive soil bacterium Bacillus subtilis. Unphosphorylated and phosphorylated forms of DegU are kno...

    Authors: Kensuke Tsukahara and Mitsuo Ogura
    Citation: BMC Microbiology 2008 8:8
  4. Pyoverdines (PVDs) are high affinity siderophores, for which the molecular mechanisms of biosynthesis, uptake and regulation have been extensively studied in Pseudomonas aeruginosa PAO1. However, the extent to wh...

    Authors: Christina D Moon, Xue-Xian Zhang, Sandra Matthijs, Mathias Schäfer, Herbert Budzikiewicz and Paul B Rainey
    Citation: BMC Microbiology 2008 8:7
  5. Microbial fuel cells (MFCs) are devices that exploit microorganisms to generate electric power from organic matter. Despite the development of efficient MFC reactors, the microbiology of electricity generation...

    Authors: Shun'ichi Ishii, Takefumi Shimoyama, Yasuaki Hotta and Kazuya Watanabe
    Citation: BMC Microbiology 2008 8:6
  6. The chlamydial developmental cycle involves the alternation between the metabolically inert elementary body (EB) and the replicating reticulate body (RB). The triggers that mediate the interchange between thes...

    Authors: Alexander Hoare, Peter Timms, Patrik M Bavoil and David P Wilson
    Citation: BMC Microbiology 2008 8:5
  7. Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling mo...

    Authors: Min Li, Amer E Villaruz, Viveka Vadyvaloo, Daniel E Sturdevant and Michael Otto
    Citation: BMC Microbiology 2008 8:4
  8. The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen Streptococcus pyogenes are functionally related in that they both hydrolyze IgG leading to impairment of opsonizing antibodies an...

    Authors: Maria Allhorn, Arne Olsén and Mattias Collin
    Citation: BMC Microbiology 2008 8:3
  9. The social amoeba Dictyostelium discoideum executes a multicellular development program upon starvation. This morphogenetic process requires the differential regulation of a large number of genes and is coordinat...

    Authors: Juan J Vicente, María Galardi-Castilla, Ricardo Escalante and Leandro Sastre
    Citation: BMC Microbiology 2008 8:1
  10. AP65 is a prominent adhesin of Trichomonas vaginalis that mediates binding of parasites to host vaginal epithelial cells (VECs). AP65 with no secretion signal sequence, membrane targeting peptide, and anchoring m...

    Authors: Ana F Garcia and JF Alderete
    Citation: BMC Microbiology 2007 7:116
  11. Most studies of the vaginal microflora have been based on culture or on qualitative molecular techniques. Here we applied existing real-time PCR formats for Lactobacillus crispatus, L. gasseri and Gardnerella vag...

    Authors: Ellen De Backer, Rita Verhelst, Hans Verstraelen, Mohammed A Alqumber, Jeremy P Burton, John R Tagg, Marleen Temmerman and Mario Vaneechoutte
    Citation: BMC Microbiology 2007 7:115
  12. The IgA1 protease of Streptococcus pneumoniae is a proteolytic enzyme that specifically cleaves the hinge regions of human IgA1, which dominates most mucosal surfaces and is the major IgA isotype in serum. This p...

    Authors: Francesca De Paolis, Elisa Beghetto, Andrea Spadoni, Francesca Montagnani, Franco Felici, Marco R Oggioni and Nicola Gargano
    Citation: BMC Microbiology 2007 7:113
  13. Enterococci have emerged as a significant cause of nosocomial infections in many parts of the world over the last decade. The most common enterococci strains present in clinical isolates are E. faecalis and E. fa...

    Authors: Chan Yean Yean, Lee Su Yin, Pattabhiraman Lalitha and Manickam Ravichandran
    Citation: BMC Microbiology 2007 7:112
  14. Along with angioplasty, autologus vein grafts are commonly used for artery bypass grafting in patients with advanced arterial stenosis and drug-resistant angina pectoris. Although initially a successful proced...

    Authors: Geoffrey TL Kloppenburg, Rick de Graaf, Gert ELM Grauls, Cathrien A Bruggeman and Frank R Stassen
    Citation: BMC Microbiology 2007 7:111
  15. Sunflower downy mildew is a major disease caused by the obligatory biotrophic oomycete Plasmopara halstedii. Little is known about the molecular mechanisms underlying its pathogenicity. In this study we used a ge...

    Authors: Mohamed Fouad Bouzidi, Francis Parlange, Paul Nicolas and Said Mouzeyar
    Citation: BMC Microbiology 2007 7:110
  16. Shiga toxins 1 and 2 (Stx1 and Stx2) are bacteriophage-encoded proteins that have been associated with hemorrhagic colitis, hemolytic uremic syndrome and other severe disease conditions. Stx1 and Stx2 are gene...

    Authors: James E Lee, Junelina Reed, Malcolm S Shields, Kathleen M Spiegel, Larry D Farrell and Peter P Sheridan
    Citation: BMC Microbiology 2007 7:109
  17. The metagenomic analysis of microbial communities holds the potential to improve our understanding of the role of microbes in clinical conditions. Recent, dramatic improvements in DNA sequencing throughput and...

    Authors: Andreas Sundquist, Saharnaz Bigdeli, Roxana Jalili, Maurice L Druzin, Sarah Waller, Kristin M Pullen, Yasser Y El-Sayed, M Mark Taslimi, Serafim Batzoglou and Mostafa Ronaghi
    Citation: BMC Microbiology 2007 7:108
  18. Sporothrix schenckii is a pathogenic, dimorphic fungus, the etiological agent of sporotrichosis, a subcutaneous lymphatic mycosis. Dimorphism in S. schenckii responds to second messengers such as cAMP and calcium...

    Authors: Liz Valle-Aviles, Shirley Valentin-Berrios, Ricardo R Gonzalez-Mendez and Nuri Rodriguez-del Valle
    Citation: BMC Microbiology 2007 7:107
  19. An available whole genome sequence for Aspergillus flavus provides the opportunity to characterize factors involved in pathogenicity and to elucidate the regulatory networks involved in aflatoxin biosynthesis. Fu...

    Authors: Zhu-Mei He, Michael S Price, Gregory R OBrian, D Ryan Georgianna and Gary A Payne
    Citation: BMC Microbiology 2007 7:104
  20. Hepatitis B virus (HBV) isolates have been classified in eight genotypes, A to H, which exhibit distinct geographical distributions. Genotypes A, D and F are predominant in Brazil, a country formed by a misceg...

    Authors: Francisco CA Mello, Francisco JD Souto, Leticia C Nabuco, Cristiane A Villela-Nogueira, Henrique Sergio M Coelho, Helena Cristina F Franz, Joao Carlos P Saraiva, Helaine A Virgolino, Ana Rita C Motta-Castro, Mabel MM Melo, Regina MB Martins and Selma A Gomes
    Citation: BMC Microbiology 2007 7:103
  21. Legionella pneumophila is a facultative intracellular bacterium, capable of replicating within the phagosomes of macrophages and monocytes, but little is known about its interaction with human lung epithelial cel...

    Authors: Hiromitsu Teruya, Futoshi Higa, Morikazu Akamine, Chie Ishikawa, Taeko Okudaira, Koh Tomimori, Naofumi Mukaida, Masao Tateyama, Klaus Heuner, Jiro Fujita and Naoki Mori
    Citation: BMC Microbiology 2007 7:102

    The Erratum to this article has been published in BMC Microbiology 2011 11:136

  22. Reuterin produced from glycerol by Lactobacillus reuteri, a normal inhabitant of the human intestine, is a broad-spectrum antimicrobial agent. It has been postulated that reuterin could play a role in the probiot...

    Authors: Valentine Cleusix, Christophe Lacroix, Sabine Vollenweider, Marc Duboux and Gwenaelle Le Blay
    Citation: BMC Microbiology 2007 7:101
  23. Bordetella holmesii is a human pathogen closely related to B. pertussis, the etiological agent of whooping cough. It is able to cause disease in immunocompromised patients, but also whooping cough-like symptoms i...

    Authors: Stefanie Link, Karin Schmitt, Dagmar Beier and Roy Gross
    Citation: BMC Microbiology 2007 7:100
  24. Community acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA) increasingly causes disease worldwide. USA300 has emerged as the predominant clone causing superficial and invasive infections in childre...

    Authors: Sarah K Highlander, Kristina G Hultén, Xiang Qin, Huaiyang Jiang, Shailaja Yerrapragada, Edward O Mason Jr, Yue Shang, Tiffany M Williams, Régine M Fortunov, Yamei Liu, Okezie Igboeli, Joseph Petrosino, Madhan Tirumalai, Akif Uzman, George E Fox, Ana Maria Cardenas…
    Citation: BMC Microbiology 2007 7:99
  25. For typing of Staphylococcus aureus, DNA sequencing of the repeat region of the protein A (spa) gene is a well established discriminatory method for outbreak investigations. Recently, it was hypothesized that thi...

    Authors: Alexander Mellmann, Thomas Weniger, Christoph Berssenbrügge, Jörg Rothgänger, Michael Sammeth, Jens Stoye and Dag Harmsen
    Citation: BMC Microbiology 2007 7:98
  26. Global patterns of gene expression of Escherichia coli K-12 during growth transitions have been deeply investigated, however, comparable studies of E. coli O157:H7 have not been explored, particularly with respec...

    Authors: Teresa M Bergholz, Lukas M Wick, Weihong Qi, James T Riordan, Lindsey M Ouellette and Thomas S Whittam
    Citation: BMC Microbiology 2007 7:97
  27. Environmental modulation of gene expression in Yersinia pestis is critical for its life style and pathogenesis. Using cDNA microarray technology, we have analyzed the global gene expression of this deadly pathoge...

    Authors: Yanping Han, Jingfu Qiu, Zhaobiao Guo, He Gao, Yajun Song, Dongsheng Zhou and Ruifu Yang
    Citation: BMC Microbiology 2007 7:96
  28. Bovine tuberculosis is a zoonotic problem in pastoral cattle and communities in Uganda. Tuberculin tests in pastoral cattle had shown a high herd but low animal prevalence, with a high proportion of avian reac...

    Authors: J Oloya, R Kazwala, A Lund, J Opuda-Asibo, B Demelash, E Skjerve, TB Johansen and B Djønne
    Citation: BMC Microbiology 2007 7:95
  29. The risk of mortality from pneumonia caused by Streptococcus pneumoniae is increased in patients with cirrhosis. However, the specific pneumococcal virulence factors and host immune defects responsible for this f...

    Authors: Katie L Propst-Graham, Laurel C Preheim, Elizabeth A Vander Top, Mary U Snitily and Martha J Gentry-Nielsen
    Citation: BMC Microbiology 2007 7:94
  30. Aeromonas spp. have been regarded as "emerging pathogens". Aeromonads possess multifactorial virulence and the production of many of these virulence determinants is associated with high cell density, a phenomenon...

    Authors: Kamlesh Jangid, Richard Kong, Milind S Patole and Yogesh S Shouche
    Citation: BMC Microbiology 2007 7:93
  31. Paracoccidioides brasiliensis ecology is not completely understood, although several pieces of evidence point to the soil as its most probable habitat. The present study aimed to investigate the fungal growth, co...

    Authors: Gisela Ramos Terçarioli, Eduardo Bagagli, Gabriela Martins Reis, Raquel Cordeiro Theodoro, Sandra De Moraes Gimenes Bosco, Severino Assis da Graça Macoris and Virgínia Bodelão Richini-Pereira
    Citation: BMC Microbiology 2007 7:92
  32. Coxiella burnetii contains the IS1111 transposase which is present 20 times in the Nine Mile phase I (9Mi/I) genome. A single PCR primer that binds to each IS element, and primers specific to a region ~500-bp ups...

    Authors: Amy M Denison, Herbert A Thompson and Robert F Massung
    Citation: BMC Microbiology 2007 7:91
  33. The predominant food borne pathogen in the western world today is Campylobacter. Campylobacter specific bacteriophages (phages) have been proposed as an alternative agent for reducing the burden of Campylobacter ...

    Authors: Vinni Mona Hansen, Hanne Rosenquist, Dorte Lau Baggesen, Stanley Brown and Bjarke Bak Christensen
    Citation: BMC Microbiology 2007 7:90
  34. Susceptibility to Bordetella pertussis infection varies widely. These differences can partly be explained by genetic host factors. HcB-28 mice are more resistant to B. pertussis infection than C3H mice, which cou...

    Authors: Sander Banus, Rob J Vandebriel, Jeroen LA Pennings, Eric R Gremmer, Piet W Wester, Henk J van Kranen, Timo M Breit, Peter Demant, Frits R Mooi, Barbara Hoebee and Tjeerd G Kimman
    Citation: BMC Microbiology 2007 7:88
  35. Salmonella enterica serovar Enteritidis has emerged as a significant foodborne pathogen throughout the world and is commonly characterized by phage typing. In Canada phage types (PT) 4, 8 and 13 predominate and i...

    Authors: Adam B Olson, Ashleigh K Andrysiak, Dobryan M Tracz, Jean Guard-Bouldin, Walter Demczuk, Lai-King Ng, Anne Maki, Frances Jamieson and Matthew W Gilmour
    Citation: BMC Microbiology 2007 7:87
  36. Rotavirus is a worldwide cause of infectious infantile diarrhea that claims over 600,000 lives annually. Recently, two new vaccine candidates have been developed but their efficacy in developing countries, sti...

    Authors: Neha Pant, Harold Marcotte, Harald Brüssow, Lennart Svensson and Lennart Hammarström
    Citation: BMC Microbiology 2007 7:86
  37. Recent research suggests that alcohol-based skin antiseptics exhibit their efficacy on the resident skin flora of the forehead in less than 10 minutes. That is why we have looked at the efficacy of two ethanol...

    Authors: Günter Kampf, Frank-Albert Pitten, Peter Heeg and Bärbel Christiansen
    Citation: BMC Microbiology 2007 7:85
  38. Salmonella enteritidis is suggested to translocate in the small intestine. In vivo it induces gene expression changes in the ileal mucosa and Peyer's patches. Stimulation of Salmonella translocation by dietary pr...

    Authors: Wendy Rodenburg, Jaap Keijer, Evelien Kramer, Susanne Roosing, Carolien Vink, Martijn B Katan, Roelof van der Meer and Ingeborg MJ Bovee-Oudenhoven
    Citation: BMC Microbiology 2007 7:84
  39. Nucleic acid amplification techniques are being used increasingly in diagnosing tuberculosis. In developing countries clinical samples are often stored for subsequent analysis since molecular tests are conduct...

    Authors: Divya Pathak, Soumitesh Chakravorty, Mahmud Hanif and Jaya Sivaswami Tyagi
    Citation: BMC Microbiology 2007 7:83
  40. The transition from viral latency to lytic growth involves complex interactions among host and viral factors, and the extent to which host physiology is buffered from the virus during induction of lysis is not...

    Authors: Robin E Osterhout, Israel A Figueroa, Jay D Keasling and Adam P Arkin
    Citation: BMC Microbiology 2007 7:82

    The Erratum to this article has been published in BMC Microbiology 2013 13:183

  41. Suppression subtractive hybridization (SSH) strategy was used with extraintestinal pathogenic Escherichia coli (EXPEC) that cause avian colibacillosis (avian pathogenic E. coli or APEC) and human urinary tract in...

    Authors: Subhashinie Kariyawasam, Jennifer A Scaccianoce and Lisa K Nolan
    Citation: BMC Microbiology 2007 7:81
  42. Bifidobacteria are found at varying prevalence in human microbiota and seem to play an important role in the human gastrointestinal tract (GIT). Bifidobacteria are highly adapted to the human GIT which is refl...

    Authors: Ueli von Ah, Valeria Mozzetti, Christophe Lacroix, Ehab E Kheadr, Ismaïl Fliss and Leo Meile
    Citation: BMC Microbiology 2007 7:79
  43. Pathogen identification in clinical routine is based on the cultivation of microbes with subsequent morphological and physiological characterisation lasting at least 24 hours. However, early and accurate ident...

    Authors: Herbert Wiesinger-Mayr, Klemens Vierlinger, Rudolf Pichler, Albert Kriegner, Alexander M Hirschl, Elisabeth Presterl, Levente Bodrossy and Christa Noehammer
    Citation: BMC Microbiology 2007 7:78
  44. Thermophilic Bacillus strains of phylogenetic Bacillus rRNA group 5 were described as a new genus Geobacillus. Their geographical distribution included oilfields, hay compost, hydrothermal vent or soils. The memb...

    Authors: Raja Noor Zaliha Raja Abd Rahman, Thean Chor Leow, Abu Bakar Salleh and Mahiran Basri
    Citation: BMC Microbiology 2007 7:77

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