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  1. Simple computerized methods that analyse variability along alignments of nucleotide or amino acid sequences can be very useful in a clinical microbiology laboratory for two main purposes. First, to optimize pr...

    Authors: Philippe Colson, Catherine Tamalet and Didier Raoult

    Citation: BMC Microbiology 2006 6:21

    Content type: Software

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  2. Cereulide, a depsipeptide structurally related to valinomycin, is responsible for the emetic type of gastrointestinal disease caused by Bacillus cereus. Recently, it has been shown that this toxin is produced by ...

    Authors: Monika Ehling-Schulz, Martina Fricker, Harald Grallert, Petra Rieck, Martin Wagner and Siegfried Scherer

    Citation: BMC Microbiology 2006 6:20

    Content type: Research article

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  3. Over the last decades molecular biologic techniques have been developed to alter the genome and proteome of Tetrahymena thermophila thereby providing the basis for recombinant protein expression including functio...

    Authors: Lutz Herrmann, Michael Erkelenz, Ingo Aldag, Arno Tiedtke and Marcus WW Hartmann

    Citation: BMC Microbiology 2006 6:19

    Content type: Research article

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  4. Flow cytometry based adherence assay is a potentially powerful but little used method in the study of bacterial binding to host structures. We have previously characterized a glycoprotein-binding activity in Stre...

    Authors: Jukka Hytönen, Sauli Haataja and Jukka Finne

    Citation: BMC Microbiology 2006 6:18

    Content type: Research article

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  5. It has been reported that some marine cyanophage are temperate and can be induced from a lysogenic phase to a lytic phase by different agents such as heavy metals. However, to date no significant reports have ...

    Authors: Lee H Lee, Doris Lui, Patricia J Platner, Shi-Fang Hsu, Tin-Chun Chu, John J Gaynor, Quinn C Vega and Bonnie K Lustigman

    Citation: BMC Microbiology 2006 6:17

    Content type: Research article

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  6. Prevention of a possible avian influenza pandemic necessitates the development of rapid diagnostic tests and the eventual production of a vaccine.

    Authors: Nitar Nwe, Qigai He, Sudarat Damrongwatanapokin, Qingyun Du, Ivanus Manopo, Yukol Limlamthong, Beau James Fenner, Lynn Spencer and Jimmy Kwang

    Citation: BMC Microbiology 2006 6:16

    Content type: Research article

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  7. Enterobacter sakazakii is a foodborne pathogen that has been associated with sporadic cases and outbreaks causing meningitis, necrotizing enterocolitis and sepsis especially in neonates. The current FDA detection...

    Authors: Angelika Lehner, Sabine Nitzsche, Pieter Breeuwer, Benjamin Diep, Karin Thelen and Roger Stephan

    Citation: BMC Microbiology 2006 6:15

    Content type: Methodology article

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  8. Arginine biosynthesis in Escherichia coli is elevated in response to nutrient limitation, stress or arginine restriction. Though control of the pathway in response to arginine limitation is largely modulated by t...

    Authors: Jeevaka P Weerasinghe, Tao Dong, Michael R Schertzberg, Mark G Kirchhof, Yuan Sun and Herb E Schellhorn

    Citation: BMC Microbiology 2006 6:14

    Content type: Research article

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  9. Brucella is an intracellular pathogen capable of infecting animals and humans. There are six recognized species of Brucella that differ in their host preference. The genomes of the three Brucella species have bee...

    Authors: Vladyslava G Ratushna, David M Sturgill, Sheela Ramamoorthy, Sherry A Reichow, Yongqun He, Raju Lathigra, Nammalwar Sriranganathan, Shirley M Halling, Stephen M Boyle and Cynthia J Gibas

    Citation: BMC Microbiology 2006 6:13

    Content type: Research article

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  10. Among the 17 genes encoding autotransporter proteins of the "surface cell antigen" (sca) family in the currently sequenced Rickettsia genomes, ompA, sca 5 (ompB) and sca 4 (gene D), have been extensively used for...

    Authors: Maxime Ngwamidiba, Guillaume Blanc, Didier Raoult and Pierre-Edouard Fournier

    Citation: BMC Microbiology 2006 6:12

    Content type: Research article

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  11. Horizontal gene transfer is an important source of genetic variation among Neisseria species and has contributed to the spread of resistance to penicillin and sulfonamide drugs in the pathogen Neisseria meningiti...

    Authors: Yvonne Qvarnstrom and Gote Swedberg

    Citation: BMC Microbiology 2006 6:11

    Content type: Research article

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  12. Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne's disease (JD) persistently infects and survives within the host macrophages. While it is established that substantial genotypic var...

    Authors: Harish K Janagama, Kwang il Jeong, Vivek Kapur, Paul Coussens and Srinand Sreevatsan

    Citation: BMC Microbiology 2006 6:10

    Content type: Research article

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  13. The classification of Brucella into species and biovars relies on phenotypic characteristics and sometimes raises difficulties in the interpretation of the results due to an absence of standardization of the typi...

    Authors: Philippe Le Flèche, Isabelle Jacques, Maggy Grayon, Sascha Al Dahouk, Patrick Bouchon, France Denoeud, Karsten Nöckler, Heinrich Neubauer, Laurence A Guilloteau and Gilles Vergnaud

    Citation: BMC Microbiology 2006 6:9

    Content type: Research article

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  14. It has been recently reported that major pathogens Staphylococcus aureus and Pseudomonas aeruginosa accelerate a normal process of cell surface syndecan-1 (Synd1) ectodomain shedding as a mechanism of host damage...

    Authors: Taissia G Popova, Bryan Millis, Chris Bradburne, Svetlana Nazarenko, Charles Bailey, Vikas Chandhoke and Serguei G Popov

    Citation: BMC Microbiology 2006 6:8

    Content type: Research article

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  15. Aspergillus niger, a saprophyte commonly found on decaying vegetation, is widely used and studied for industrial purposes. Despite its place as one of the most important organisms for commercial applications, the...

    Authors: Natalia Semova, Reginald Storms, Tricia John, Pascale Gaudet, Peter Ulycznyj, Xiang Jia Min, Jian Sun, Greg Butler and Adrian Tsang

    Citation: BMC Microbiology 2006 6:7

    Content type: Research article

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  16. Trichomonosis caused by Trichomonas vaginalis is the number one, non-viral sexually transmitted disease (STD) that affects more than 250 million people worldwide. Immunoglobulin A (IgA) has been implicated in res...

    Authors: V Mundodi, AS Kucknoor, T-H Chang and JF Alderete

    Citation: BMC Microbiology 2006 6:6

    Content type: Research article

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  17. Chromium is a transition metal most commonly found in the environment in its trivalent [Cr(III)] and hexavalent [Cr(VI)] forms. The EPA maximum total chromium contaminant level for drinking water is 0.1 mg/l (...

    Authors: Rene' N Horton, William A Apel, Vicki S Thompson and Peter P Sheridan

    Citation: BMC Microbiology 2006 6:5

    Content type: Research article

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  18. Fusarium head blight (FHB) is a disease of cereal crops, which has a severe impact on wheat and barley production worldwide. Apart from reducing the yield and impairing grain quality, FHB leads to contaminatio...

    Authors: Christoph Brandfass and Petr Karlovsky

    Citation: BMC Microbiology 2006 6:4

    Content type: Methodology article

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  19. A potentially lethal flux of hydrogen peroxide (H2O2) is continuously generated during aerobic metabolism. It follows that aerobic organisms have equipped themselves with specific H2O2 dismutases and H2O2 reducta...

    Authors: Bjorn Vergauwen, Mark Herbert and Jozef J Van Beeumen

    Citation: BMC Microbiology 2006 6:3

    Content type: Research article

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  20. Coxiella burnetii, the bacterium causing Q fever, is an obligate intracellular biosafety level 3 agent. Detection and quantification of these bacteria with conventional methods is time consuming and dangerous. Du...

    Authors: Silke R Klee, Judith Tyczka, Heinz Ellerbrok, Tatjana Franz, Sonja Linke, Georg Baljer and Bernd Appel

    Citation: BMC Microbiology 2006 6:2

    Content type: Research article

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  21. There is an increasing interest to better understand endosymbiont capabilities in insects both from an ecological point of view and for pest control. Blochmannia floridanus provides important nutrients for its ho...

    Authors: Peter Gaudermann, Ina Vogl, Evelyn Zientz, Francisco J Silva, Andres Moya, Roy Gross and Thomas Dandekar

    Citation: BMC Microbiology 2006 6:1

    Content type: Research article

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  22. Precise identification of bacterial pathogens at the strain level is essential for epidemiological purposes. In Streptococcus pneumoniae, the existence of 90 different serotypes makes the typing particularly diff...

    Authors: Jean-Louis Koeck, Berthe-Marie Njanpop-Lafourcade, Sonia Cade, Emmanuelle Varon, Lassana Sangare, Samina Valjevac, Gilles Vergnaud and Christine Pourcel

    Citation: BMC Microbiology 2005 5:66

    Content type: Research article

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  23. The filamentous fungus Sordaria macrospora forms complex three-dimensional fruiting bodies called perithecia that protect the developing ascospores and ensure their proper discharge. In previous microarray analys...

    Authors: Minou Nowrousian and Patricia Cebula

    Citation: BMC Microbiology 2005 5:64

    Content type: Research article

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  24. Group A streptococcal (GAS) infections can lead to the development of severe post-infectious sequelae, such as rheumatic fever (RF) and rheumatic heart disease (RHD). RF and RHD are a major health concern in d...

    Authors: Nonglak Yoonim, Colleen Olive, Chulabhorn Pruksachatkunakorn, Michael F Good and Sumalee Pruksakorn

    Citation: BMC Microbiology 2005 5:63

    Content type: Research article

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  25. The microbiological diagnosis of bacterial vaginosis is usually made using Nugent's criteria, a useful but rather laborious scoring system based on counting bacterial cell types on Gram stained slides of vagin...

    Authors: Rita Verhelst, Hans Verstraelen, Geert Claeys, Gerda Verschraegen, Leen Van Simaey, Catharine De Ganck, Ellen De Backer, Marleen Temmerman and Mario Vaneechoutte

    Citation: BMC Microbiology 2005 5:61

    Content type: Research article

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  26. Analysis of the first reported complete genome sequence of Bifidobacterium longum NCC2705, an actinobacterium colonizing the gastrointestinal tract, uncovered its proteomic relatedness to Streptomyces coelicolor ...

    Authors: Lionel Guy, Dimitri Karamata, Philippe Moreillon and Claude-Alain H Roten

    Citation: BMC Microbiology 2005 5:60

    Content type: Research article

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  27. Polyamines such as spermine and spermidine are required for growth of Escherichia coli; they interact with nucleic acids, and they bind to ribosomes. Polyamines block porins and decrease membrane permeability, ac...

    Authors: Elizabeth Yohannes, Amy E Thurber, Jessica C Wilks, Daniel P Tate and Joan L Slonczewski

    Citation: BMC Microbiology 2005 5:59

    Content type: Research article

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  28. We present an overview of bacterial non-classical secretion and a prediction method for identification of proteins following signal peptide independent secretion pathways. We have compiled a list of proteins f...

    Authors: Jannick D Bendtsen, Lars Kiemer, Anders Fausbøll and Søren Brunak

    Citation: BMC Microbiology 2005 5:58

    Content type: Research article

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  29. Two putative methionine aminopeptidase genes, map (essential) and yflG (non-essential), were identified in the genome sequence of Bacillus subtilis. We investigated whether they can function as methionine aminope...

    Authors: CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles and Antoine Danchin

    Citation: BMC Microbiology 2005 5:57

    Content type: Research article

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  30. It has been speculated that the γ-glutamyl transpeptidase (ggt) gene is present only in Neisseria meningitidis and not among related species such as Neisseria gonorrhoeae and Neisseria lactamica, because N. menin...

    Authors: Hideyuki Takahashi and Haruo Watanabe

    Citation: BMC Microbiology 2005 5:56

    Content type: Research article

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  31. More than 200 studies related to nucleic acid amplification (NAA) tests to detect Mycobacterium tuberculosis directly from clinical specimens have appeared in the world literature since this technology was first ...

    Authors: Laura L Flores, Madhukar Pai, John M Colford Jr and Lee W Riley

    Citation: BMC Microbiology 2005 5:55

    Content type: Research article

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  32. Formation of alternative structures in mRNA in response to external stimuli, either direct or mediated by proteins or other RNAs, is a major mechanism of regulation of gene expression in bacteria. This mechani...

    Authors: Alexander V Seliverstov, Harald Putzer, Mikhail S Gelfand and Vassily A Lyubetsky

    Citation: BMC Microbiology 2005 5:54

    Content type: Research article

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  33. Microbial biofilms exist all over the natural world, a distribution that is paralleled by metal cations and oxyanions. Despite this reality, very few studies have examined how biofilms withstand exposure to th...

    Authors: Joe J Harrison, Raymond J Turner and Howard Ceri

    Citation: BMC Microbiology 2005 5:53

    Content type: Methodology article

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  34. Bacillus thuringiensis is a bacterium known for producing protein crystals with insecticidal properties. These toxins are widely sought after for controlling agricultural pests due to both their specificity and t...

    Authors: Joanne Rampersad and David Ammons

    Citation: BMC Microbiology 2005 5:52

    Content type: Research article

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  35. The current model for the developmental cycle of Streptomyces confluent cultures on agar surface is based on the assumption that the only differentiation takes place along the transverse axis (bottom-up): a veget...

    Authors: Angel Manteca, Marisol Fernandez and Jesus Sanchez

    Citation: BMC Microbiology 2005 5:51

    Content type: Research article

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  36. The sexually transmitted disease, gonorrhea, is a serious health problem in developed as well as in developing countries, for which treatment continues to be a challenge. The recent completion of the genome se...

    Authors: Thomas Brettin, Michael R Altherr, Ying Du, Roxie M Mason, Alexandra Friedrich, Laura Potter, Chris Langford, Thomas J Keller, Jason Jens, Heather Howie, Nathan J Weyand, Susan Clary, Kimberly Prichard, Susi Wachocki, Erica Sodergren, Joseph P Dillard…

    Citation: BMC Microbiology 2005 5:50

    Content type: Methodology article

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  37. The metabolism of the rigid bacterial cell wall heteropolymer peptidoglycan is a dynamic process requiring continuous biosynthesis and maintenance involving the coordination of both lytic and synthetic enzymes...

    Authors: Joel T Weadge, John M Pfeffer and Anthony J Clarke

    Citation: BMC Microbiology 2005 5:49

    Content type: Research article

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  38. The oomycete Saprolegnia parasitica is one of the most economically important fish pathogens. There is a dramatic recrudescence of Saprolegnia infections in aquaculture since the use of the toxic organic dye mala...

    Authors: Trudy Torto-Alalibo, Miaoying Tian, Kamal Gajendran, Mark E Waugh, Pieter van West and Sophien Kamoun

    Citation: BMC Microbiology 2005 5:46

    Content type: Research article

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  39. Heterologous prime-boost immunization protocols using different gene expression systems have proven to be successful tools in protecting against various diseases in experimental animal models. The main reason ...

    Authors: SE Aleshin, AV Timofeev, MV Khoretonenko, LG Zakharova, GV Pashvykina, JR Stephenson, AM Shneider and AD Altstein

    Citation: BMC Microbiology 2005 5:45

    Content type: Research article

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  40. Population-based bacterial genetics using repeated DNA loci is an efficient approach to study the biodiversity and phylogeographical structure of human pathogens, such as Mycobacterium tuberculosis, the agent of ...

    Authors: Thierry Zozio, Caroline Allix, Selami Gunal, Zeynep Saribas, Alpaslan Alp, Riza Durmaz, Maryse Fauville-Dufaux, Nalin Rastogi and Christophe Sola

    Citation: BMC Microbiology 2005 5:44

    Content type: Research article

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  41. Pseudomonas aeruginosa is the leading cause of morbidity and mortality in patients with cystic fibrosis (CF). With chronicity of infection, the organism resides as a biofilm, shows multi-drug resistance, diversif...

    Authors: Gunjan Agarwal, Arti Kapil, Susheel Kumar Kabra, Bimal Kumar Das and Sada Nand Dwivedi

    Citation: BMC Microbiology 2005 5:43

    Content type: Software

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  42. Salmonella enterica subspecies I includes several closely related serovars which differ in host ranges and ability to cause disease. The basis for the diversity in host range and pathogenic potential of the serov...

    Authors: Vesela Encheva, Robin Wait, Saheer E Gharbia, Shajna Begum and Haroun N Shah

    Citation: BMC Microbiology 2005 5:42

    Content type: Research article

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  43. Metal reduction is thought to take place at or near the bacterial outer membrane and, thus, outer membrane proteins in the model dissimilatory metal-reducing organism Geobacter sulfurreducens are of interest to u...

    Authors: Eman Afkar, Gemma Reguera, Marianne Schiffer and Derek R Lovley

    Citation: BMC Microbiology 2005 5:41

    Content type: Research article

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  44. Genome-scale flux models are useful tools to represent and analyze microbial metabolism. In this work we reconstructed the metabolic network of the lactic acid bacteria Lactococcus lactis and developed a genome-s...

    Authors: Ana Paula Oliveira, Jens Nielsen and Jochen Förster

    Citation: BMC Microbiology 2005 5:39

    Content type: Research article

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