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  1. The diagnosis of invasive candidiasis is difficult because there are no specific clinical manifestations of the disease and colonization and infection are difficult to distinguish. In the last decade, much eff...

    Authors: Ana Laín, Natalia Elguezabal, Sonia Brena, Juan Carlos García-Ruiz, Amalia del Palacio, María D Moragues and José Pontón

    Citation: BMC Microbiology 2007 7:35

    Content type: Research article

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  2. Pseudomonas aeruginosa frequently colonizes and is responsible for severe ventilator-associated pneumonia in intubated patients. A quorum-sensing (QS) circuit, depending on the production of the two QS-signaling ...

    Authors: Sabine Favre-Bonté, Eric Chamot, Thilo Köhler, Jacques-A Romand and Christian van Delden

    Citation: BMC Microbiology 2007 7:33

    Content type: Research article

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  3. In recent years there has been renewed interest in the use of air ionisers to control of the spread of airborne infection. One characteristic of air ions which has been widely reported is their apparent biocid...

    Authors: Louise A Fletcher, Lindsey F Gaunt, Clive B Beggs, Simon J Shepherd, P Andrew Sleigh, Catherine J Noakes and Kevin G Kerr

    Citation: BMC Microbiology 2007 7:32

    Content type: Research article

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  4. Contagious bovine pleuropneumonia (CBPP) caused by Mycoplasma mycoides subsp. mycoides small-colony type (SC) is among the most serious threats for livestock producers in Africa. Glycerol metabolism-associated H2

    Authors: Edy M Vilei, Ivone Correia, M Helena Ferronha, Daniela F Bischof and Joachim Frey

    Citation: BMC Microbiology 2007 7:31

    Content type: Research article

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  5. The program eBURST uses multilocus sequence typing data to divide bacterial populations into groups of closely related strains (clonal complexes), predicts the founding genotype of each group, and displays the...

    Authors: Katherine ME Turner, William P Hanage, Christophe Fraser, Thomas R Connor and Brian G Spratt

    Citation: BMC Microbiology 2007 7:30

    Content type: Research article

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  6. Paracoccidioides brasiliensis is a human pathogen with a broad distribution in Latin America. The fungus is thermally dimorphic with two distinct forms corresponding to completely different lifestyles. Upon eleva...

    Authors: Karinne P Bastos, Alexandre M Bailão, Clayton L Borges, Fabricia P Faria, Maria SS Felipe, Mirelle G Silva, Wellington S Martins, Rogério B Fiúza, Maristela Pereira and Célia MA Soares

    Citation: BMC Microbiology 2007 7:29

    Content type: Research article

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  7. MLVA (multiple-locus variable-number tandem repeat analysis) is a reliable typing technique introduced recently to differentiate also isolates of Enterococcus faecium. We used the established VNTR (variable numbe...

    Authors: Guido Werner, Ingo Klare and Wolfgang Witte

    Citation: BMC Microbiology 2007 7:28

    Content type: Research article

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  8. Clinical isolates of the gastric pathogen Helicobacter pylori display a high level of genetic macro- and microheterogeneity, featuring a panmictic, rather than clonal structure. The ability of H. pylori to surviv...

    Authors: Justin G Hovey, Emily L Watson, Melanie L Langford, Ellen Hildebrandt, Sangeetha Bathala, Jeffrey R Bolland, Domenico Spadafora, George L Mendz and David J McGee

    Citation: BMC Microbiology 2007 7:26

    Content type: Research article

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  9. The presence of β-lactamases in Y. enterocolitica has been reported to vary with serovars, biovars and geographical origin of the isolates. An understanding of the β-lactamases in other related species is importa...

    Authors: Shilpi Mittal, Sarita Mallik, Sachin Sharma and Jugsharan S Virdi

    Citation: BMC Microbiology 2007 7:25

    Content type: Research article

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  10. Two component lantibiotics, such as the plasmid-encoded lacticin 3147 produced by Lactococcus lactis DPC3147 and staphylococcin C55 produced by Staphylococcus aureus C55, represent an emerging subgroup of bacteri...

    Authors: Eileen B O'Connor, Paul D Cotter, Paula O'Connor, Orla O'Sullivan, John R Tagg, R Paul Ross and Colin Hill

    Citation: BMC Microbiology 2007 7:24

    Content type: Research article

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  11. The facultative, intracellular bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a serious infectious disease of humans and animals. We identified and categorized tandem repeat arrays and...

    Authors: Jana M U'Ren, James M Schupp, Talima Pearson, Heidie Hornstra, Christine L Clark Friedman, Kimothy L Smith, Rebecca R Leadem Daugherty, Shane D Rhoton, Ben Leadem, Shalamar Georgia, Michelle Cardon, Lynn Y Huynh, David DeShazer, Steven P Harvey, Richard Robison, Daniel Gal…

    Citation: BMC Microbiology 2007 7:23

    Content type: Research article

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  12. Epstein-Barr virus (EBV) DNA load monitoring is known to be useful for the diagnosis and monitoring of EBV-associated diseases. The aim of this study is to compare the performance of two real-time PCR assays f...

    Authors: Francesca Perandin, Elisabetta Cariani, Caterina Patrizia Pollara and Nino Manca

    Citation: BMC Microbiology 2007 7:22

    Content type: Research article

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  13. Enterohemorrhagic E. coli (EHEC), a subgroup of Shiga toxin (Stx) producing E. coli (STEC), may cause severe enteritis and hemolytic uremic syndrome (HUS) and is transmitted orally via contaminated foods or from ...

    Authors: Sina M Coldewey, Maike Hartmann, Dorothea S Schmidt, Uta Engelking, Sya N Ukena and Florian Gunzer

    Citation: BMC Microbiology 2007 7:21

    Content type: Research article

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  14. In V. cholerae, the biogenesis of capsule polysaccharide is poorly understood. The elucidation of capsule structure and biogenesis is critical to understanding the evolution of surface polysaccharide and the inte...

    Authors: Yuansha Chen, Peter Bystricky, Jacob Adeyeye, Pinaki Panigrahi, Afsar Ali, Judith A Johnson, CA Bush, JG Morris Jr and OC Stine

    Citation: BMC Microbiology 2007 7:20

    Content type: Research article

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  15. The bacterial biothreat agents Burkholderia mallei and Burkholderia pseudomallei are the cause of glanders and melioidosis, respectively. Genomic and epidemiological studies have shown that B. mallei is a recentl...

    Authors: Rachaneeporn Tiyawisutsri, Matthew TG Holden, Sarinna Tumapa, Sirirat Rengpipat, Simon R Clarke, Simon J Foster, William C Nierman, Nicholas PJ Day and Sharon J Peacock

    Citation: BMC Microbiology 2007 7:19

    Content type: Research article

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  16. Mycobacterium avium subsp. paratuberculosis (Map) causes paratuberculosis in animals and is suspected of causing Crohn's Disease in humans. Characterization of strains led to classify paratuberculosis isolates in...

    Authors: Iker Sevilla, Joseba M Garrido, Marivi Geijo and Ramon A Juste

    Citation: BMC Microbiology 2007 7:18

    Content type: Research article

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  17. In order to study the mechanism of U(VI) reduction, the effect of deleting c-type cytochrome genes on the capacity of Geobacter sulfurreducens to reduce U(VI) with acetate serving as the electron donor was invest...

    Authors: Evgenya S Shelobolina, Maddalena V Coppi, Anton A Korenevsky, Laurie N DiDonato, Sara A Sullivan, Hiromi Konishi, Huifang Xu, Ching Leang, Jessica E Butler, Byoung-Chan Kim and Derek R Lovley

    Citation: BMC Microbiology 2007 7:16

    Content type: Research article

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  18. Extra-cellular shear force is an important environmental parameter that is significant both medically and in the space environment. Escherichia coli cells grown in a low-shear modeled microgravity (LSMMG) environ...

    Authors: Don L Tucker, C Mark Ott, Stephen Huff, Yuriy Fofanov, Duane L Pierson, Richard C Willson and George E Fox

    Citation: BMC Microbiology 2007 7:15

    Content type: Research article

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  19. Mycobacterium avium is an environmental mycobacterium that can be divided into the subspecies avium, hominissuis, paratuberculosis and silvaticum. Some M. avium subspecies are opportunistic pathogens for animals ...

    Authors: Tone Bjordal Johansen, Ingrid Olsen, Merete Rusås Jensen, Ulf R Dahle, Gudmund Holstad and Berit Djønne

    Citation: BMC Microbiology 2007 7:14

    Content type: Research article

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  20. Shiga toxin-producing Escherichia coli (STEC) have emerged as pathogens that can cause food-borne infections and severe and potentially fatal illnesses in humans, such as haemorrhagic colitis (HC) and haemolytic ...

    Authors: Azucena Mora, Miguel Blanco, Jesús E Blanco, Ghizlane Dahbi, Cecilia López, Paula Justel, María Pilar Alonso, Aurora Echeita, María Isabel Bernárdez, Enrique A González and Jorge Blanco

    Citation: BMC Microbiology 2007 7:13

    Content type: Research article

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  21. Tetrahymena thermophila is one of the best characterized unicellular eukaryotes and its genome is sequenced in its entirety. However, the AT-richness of the genome and an unusual codon usage cause problems in clo...

    Authors: Thomas Weide, Ulrike Bockau, Angelika Rave, Lutz Herrmann and Marcus WW Hartmann

    Citation: BMC Microbiology 2007 7:12

    Content type: Methodology article

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  22. The human bacterial pathogen Campylobacter jejuni contains two subspecies: C. jejuni subsp. jejuni (Cjj) and C. jejuni subsp. doylei (Cjd). Although Cjd strains are isolated infrequently in many parts of the worl...

    Authors: William G Miller, Craig T Parker, Sekou Heath and Albert J Lastovica

    Citation: BMC Microbiology 2007 7:11

    Content type: Methodology article

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  23. To be transmitted by its mosquito vector, dengue virus (DENV) must infect midgut epithelial cells, replicate and disseminate into the hemocoel, and finally infect the salivary glands, which is essential for tr...

    Authors: Ma Isabel Salazar, Jason H Richardson, Irma Sánchez-Vargas, Ken E Olson and Barry J Beaty

    Citation: BMC Microbiology 2007 7:9

    Content type: Research article

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  24. The ability of catecholamines to stimulate bacterial growth was first demonstrated just over a decade ago. Little is still known however, concerning the nature of the putative bacterial adrenergic and/or dopam...

    Authors: Primrose PE Freestone, Richard D Haigh and Mark Lyte

    Citation: BMC Microbiology 2007 7:8

    Content type: Research article

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  25. The influence of the membrane-bound AAA+ protease FtsH on membrane and cytoplasmic proteins of Corynebacterium glutamicum was investigated in this study. For the analysis of the membrane fraction, anion exchange ...

    Authors: Alja Lüdke, Reinhard Krämer, Andreas Burkovski, Daniela Schluesener and Ansgar Poetsch

    Citation: BMC Microbiology 2007 7:6

    Content type: Research article

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  26. The role of Aspergillus fumigatus mycotoxins in the colonization of the respiratory tract by conidia has not been studied extensively, even though patients at risk from invasive aspergillosis frequently exhibit r...

    Authors: Khaled Khoufache, Olivier Puel, Nicolas Loiseau, Marcel Delaforge, Danièle Rivollet, André Coste, Catherine Cordonnier, Estelle Escudier, Françoise Botterel and Stéphane Bretagne

    Citation: BMC Microbiology 2007 7:5

    Content type: Research article

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  27. Mycobacteria have developed a number of pathways that provide partial protection against both reactive oxygen species (ROS) and reactive nitrogen species (RNS). We recently identified a locus in Mycobacterium mar...

    Authors: Selvakumar Subbian, Parmod K Mehta, Suat LG Cirillo and Jeffrey D Cirillo

    Citation: BMC Microbiology 2007 7:4

    Content type: Research article

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  28. The type III secretion system (TTSS) is an important virulence determinant of Gram-negative bacterial pathogens. It enables the injection of effector proteins into the cytosol of eukaryotic cells. These effect...

    Authors: Yakhya Dieye, Jessica L Dyszel, Rebin Kader and Brian MM Ahmer

    Citation: BMC Microbiology 2007 7:3

    Content type: Research article

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  29. The glutamate synthase operon (gltBDF) contributes to one of the two main pathways of ammonia assimilation in Escherichia coli. Of the seven most-global regulators, together affecting expression of about half of ...

    Authors: Ligi Paul, Pankaj K Mishra, Robert M Blumenthal and Rowena G Matthews

    Citation: BMC Microbiology 2007 7:2

    Content type: Research article

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  30. Francisella tularensis is a gram negative, facultative intracellular bacterium that is the etiological agent of tularemia. F. novicida is closely related to F. tularensis but has low virulence for humans while be...

    Authors: Olle M de Bruin, Jagjit S Ludu and Francis E Nano

    Citation: BMC Microbiology 2007 7:1

    Content type: Research article

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  31. The Burkholderia cenocepacia CepIR quorum sensing system has been shown to positively and negatively regulate genes involved in siderophore production, protease expression, motility, biofilm formation and virulen...

    Authors: Catherine E Chambers, Erika I Lutter, Michelle B Visser, Peggy PY Law and Pamela A Sokol

    Citation: BMC Microbiology 2006 6:104

    Content type: Research article

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  32. Different gene expression patterns correlate with the altered phenotype in biofilm-associated bacteria. Iron and iron-linked genes are thought to play a key-role in biofilm formation. The expression of Fe-link...

    Authors: Caroline Massonet, Valerie Pintens, Rita Merckx, Jozef Anné, Elke Lammertyn and Johan Van Eldere

    Citation: BMC Microbiology 2006 6:103

    Content type: Research article

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  33. Random gene inactivation used to identify cellular functions associated with virulence and survival of Brucella spp has relied heavily upon the use of the transposon Tn5 that integrates at G/C base pairs. Transpo...

    Authors: Qingmin Wu, Jianwu Pei, Carol Turse and Thomas A Ficht

    Citation: BMC Microbiology 2006 6:102

    Content type: Research article

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  34. In sub-Saharan Africa community-acquired non-typhoidal Salmonella (NTS) is a major cause of high morbidity and death among children under 5 years of age especially from resource poor settings. The emergence of...

    Authors: Samuel Kariuki, Gunturu Revathi, Nyambura Kariuki, John Kiiru, Joyce Mwituria and Charles A Hart

    Citation: BMC Microbiology 2006 6:101

    Content type: Research article

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  35. Enterobacter sakazakii is the causative agent of rare but severe food-borne infections associated with meningitis, necrotizing enterocolitis and sepsis in infants. Rehydrated powdered infant formulae have been im...

    Authors: Sylviane Derzelle and Françoise Dilasser

    Citation: BMC Microbiology 2006 6:100

    Content type: Methodology article

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  36. E. coli O157 is a bacterial pathogen that is shed by cattle and can cause severe disease in humans. Phage type (PT) 21/28 is a subtype of E. coli O157 that is found across Scotland and is associated with particul...

    Authors: Jo EB Halliday, Margo E Chase-Topping, Michael C Pearce, Iain J McKendrick, Lesley Allison, Dave Fenlon, Chris Low, Dominic J Mellor, George J Gunn and Mark EJ Woolhouse

    Citation: BMC Microbiology 2006 6:99

    Content type: Research article

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  37. A majority of bacterial genes belong to tight clusters and operons, which complicates gene functional studies using conventional knock-out methods. Antisense agents can down-regulate the expression of genes wi...

    Authors: Rikard Dryselius, Abbas Nikravesh, Agne Kulyté, Shan Goh and Liam Good

    Citation: BMC Microbiology 2006 6:97

    Content type: Research article

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  38. Coagulase-negative Staphylococcus epidermidis has become a major frequent cause of infections in relation to the use of implanted medical devices. The pathogenicity of S. epidermidis has been attributed to its ca...

    Authors: Zhiqiang Qin, Jian Zhang, Bin Xu, Lili Chen, Yang Wu, Xiaomei Yang, Xu Shen, Soeren Molin, Antoine Danchin, Hualiang Jiang and Di Qu

    Citation: BMC Microbiology 2006 6:96

    Content type: Research article

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  39. Leptospira is the causative genus of the disease, leptospirosis. Species identification of pathogenic Leptospira in the past was generally performed by either DNA-DNA hybridisation or 16s rRNA gene sequencing. Bo...

    Authors: Andrew T Slack, Meegan L Symonds, Michael F Dohnt and Lee D Smythe

    Citation: BMC Microbiology 2006 6:95

    Content type: Research article

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  40. Enterobacter sakazakii is an emergent pathogen that has been associated with neonatal infections through contaminated powdered infant milk formula. The species was defined by Farmer et al. (1980) who described 15...

    Authors: Carol Iversen, Mike Waddington, Jim J Farmer III and Stephen J Forsythe

    Citation: BMC Microbiology 2006 6:94

    Content type: Research article

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  41. Quorum sensing is a form of cell-to-cell communication that allows bacteria to control a wide range of physiological processes in a population density-dependent manner. Production of peptide antibiotics is one...

    Authors: Bettina H Rohde and Luis EN Quadri

    Citation: BMC Microbiology 2006 6:93

    Content type: Research article

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  42. Species of the tick-transmitted spirochete group Borrelia burgdorferi sensu lato (B. burgdorferi) cause Lyme borreliosis. Acute borrelial infection of the skin has unusual characteristics with only a mild local i...

    Authors: Helena Tuominen-Gustafsson, Markus Penttinen, Jukka Hytönen and Matti K Viljanen

    Citation: BMC Microbiology 2006 6:92

    Content type: Research article

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  43. Plasmodium vivax is the most widespread human malaria parasite. However, genetic information about its pathogenesis is limited at present, due to the lack of a reproducible in vitro cultivation method. Sequencing...

    Authors: James T Njuguna, Marwa Nassar, Achim Hoerauf and Annette E Kaiser

    Citation: BMC Microbiology 2006 6:91

    Content type: Research article

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  44. Molecular typing of Mycobacterium tuberculosis strains has become a valuable tool in the epidemiology of tuberculosis (TB) by allowing detection of outbreaks, tracking of epidemics, identification of genotypes an...

    Authors: Liselotte Aristimuño, Raimond Armengol, Alberto Cebollada, Mercedes España, Alexis Guilarte, Carmen Lafoz, María A Lezcano, María J Revillo, Carlos Martín, Carmen Ramírez, Nalin Rastogi, Janet Rojas, Albina Vázques de Salas, Christophe Sola and Sofía Samper

    Citation: BMC Microbiology 2006 6:90

    Content type: Research article

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