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Microbial biochemistry, physiology and metabolism

This section aims to publish studies relating to microbial biochemistry, physiology and metabolism, including enzymology, metabolic pathways and regulation, growth, development and stress responses.

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  1. The production of methane by methanogens is dependent on numerous iron-sulfur (Fe-S) cluster proteins; yet, the machinery involved in Fe-S cluster biogenesis in methanogens remains largely unknown. Methanogen ...

    Authors: Thomas M. Deere, Divya Prakash, Faith H. Lessner, Evert C. Duin and Daniel J. Lessner

    Citation: BMC Microbiology 2020 20:323

    Content type: Research article

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  2. Stenotrophomonas maltophilia, an opportunistic pathogen, is ubiquitously present in various environments, signifying its high capability of environmental adaptation. Two-component regulatory system (TCS) is a pow...

    Authors: Hsu-Feng Lu, Bo-Kuan Wu, Yi-Wei Huang, Ming-Zhe Lee, Ming-Fang Li, Hsu-Jung Ho, Hung-Chi Yang and Tsuey-Ching Yang

    Citation: BMC Microbiology 2020 20:312

    Content type: Research article

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  3. Bifidobacteria are important probiotics; some of the beneficial effects of bifidobacteria are achieved by the hydrolysis of glycans in the human gut. However, because the diet of breastfed infants typically la...

    Authors: Zeyu Kan, Baolong Luo, Jingjing Cai, Yan Zhang, Fengwei Tian and Yongqing Ni

    Citation: BMC Microbiology 2020 20:277

    Content type: Research article

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  4. Clostridioides (formerly Clostridium) difficile infection is the leading cause of antibiotic-associated colitis. Studies have demonstrated that C. difficile toxin A (TcdA) can cause apoptosis of many human cell t...

    Authors: Jinhua Liang, Yongzhong Ning, Li Dong, Xiufeng Ma, Shu Li, Heran Yang, Qi Li, Ling Chen, Lingjuan Gao and Yanmin Xu

    Citation: BMC Microbiology 2020 20:274

    Content type: Research article

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  5. Atrazine is one of the most widespread chlorinated herbicides, leaving large bulks in soils and groundwater. The biodegradation of atrazine by bacteria is well described, but many aspects of the fungal metabol...

    Authors: Caroline Henn, Diego Alves Monteiro, Mauricio Boscolo, Roberto da Silva and Eleni Gomes

    Citation: BMC Microbiology 2020 20:266

    Content type: Research article

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  6. The integrity of cell wall structure is highly significant for the in vivo survival of mycobacteria. We hypothesized that changes in morphology may indicate changes in cell wall metabolism and identified an aceE ...

    Authors: Suting Chen, Tianlu Teng, Shuan Wen, Tingting Zhang and Hairong Huang

    Citation: BMC Microbiology 2020 20:259

    Content type: Research article

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  7. Probiotics have been reported to reduce total cholesterol levels in vitro, but more evidence is needed to determine the clinical relevance of this activity. Chinese traditional fermented pickles are a good sou...

    Authors: Zhi-yao Zheng, Fei-Wei Cao, Wei-jun Wang, Jing Yu, Chen Chen, Bo Chen, Jian-xin Liu, Jenni Firrman, John Renye and Da-xi Ren

    Citation: BMC Microbiology 2020 20:239

    Content type: Research article

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  8. Perkinsosis is a major disease affecting the commercially important marine mollusk Ruditapes philippinarum (Manila clam) in Asian waters. In this study, we investigated the morphological characteristics of Perkin...

    Authors: Dinesh Gajamange, Seung-Hyeon Kim, Kwang-Sik Choi, Carlos Azevedo and Kyung-Il Park

    Citation: BMC Microbiology 2020 20:238

    Content type: Research article

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    The Correction to this article has been published in BMC Microbiology 2020 20:289

  9. Probiotics are being considered as valuable microorganisms related to human health. Hu sheep is referred as one of the important sheep breeds in China. Goat milk produced by Hu sheep is characterized with high...

    Authors: Taohong Chen, Leli Wang, Qinxin Li, Yingjie Long, Yuming Lin, Jie Yin, Yan Zeng, Le Huang, Tingyu Yao, Muhammad Nazeer Abbasi, Huansheng Yang, Qiye Wang, Congjia Tang, Tahir Ali Khan, Qiuyue Liu, Jia Yin…

    Citation: BMC Microbiology 2020 20:228

    Content type: Research article

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  10. Cyanobacteria are well known for their inherent ability to serve as atmospheric nitrogen fixers and as bio-fertilizers; however, increased contaminants in aquatic ecosystem significantly decline the growth and...

    Authors: Sanjesh Tiwari, Anuradha Patel and Sheo Mohan Prasad

    Citation: BMC Microbiology 2020 20:206

    Content type: Research article

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  11. Euglena is a new super health food resource that is rich in the natural polysaccharide paramylon, a linear β-1,3-glucan with various biological activities including activity on the immune system in different cell...

    Authors: Qingqing Guo, Decheng Bi, Mingcan Wu, Boming Yu, Lang Hu, Chenchen Liu, Liang Gu, Hui Zhu, Anping Lei, Xu Xu and Jiangxin Wang

    Citation: BMC Microbiology 2020 20:171

    Content type: Research article

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  12. Dietary intervention has been reported to improve intestinal health. The intestinal microbiota of newborn animals plays a fundamental role in the development of intestinal function and the innate immune system...

    Authors: Jipeng Jin, Jianlei Jia, Liping Zhang, Qian Chen, Xiaoyan Zhang, Weibo Sun, Cunming Ma, Fafang Xu, Shoujun Zhan, Limin Ma, Guihua Zhou and Qiaoxi Chen

    Citation: BMC Microbiology 2020 20:169

    Content type: Research article

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  13. Viridans group streptococci of the Streptococcus mitis-oralis subgroup are important endovascular pathogens. They can rapidly develop high-level and durable non-susceptibility to daptomycin both in vitro and in v...

    Authors: Allison Parrett, Joseph M. Reed, Stewart G. Gardner, Nagendra N. Mishra, Arnold S. Bayer, Robert Powers and Greg A. Somerville

    Citation: BMC Microbiology 2020 20:162

    Content type: Research article

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  14. Quaternary ammonium compound based disinfectants are commonly used in pig and poultry husbandry to maintain farm hygiene. However, studies have shown that subinhibitory concentrations of these disinfectants ma...

    Authors: H. Maertens, K. Demeyere, K. De Reu, J. Dewulf, D. Vanhauteghem, E. Van Coillie and E. Meyer

    Citation: BMC Microbiology 2020 20:155

    Content type: Research article

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  15. Bio-based succinic acid holds promise as a sustainable platform chemical. Its production through microbial fermentation concurs with the fixation of CO2, through the carboxylation of phosphoenolpyruvate. Here, we...

    Authors: Jeroen Girwar Koendjbiharie, Wilbert Berend Post, Martí Munar Palmer and Richard van Kranenburg

    Citation: BMC Microbiology 2020 20:149

    Content type: Research article

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  16. Pyruvate oxidase (Pox) is an important enzyme in bacterial metabolism for increasing ATP production and providing a fitness advantage via hydrogen peroxide production. However, few Pox enzymes have been charac...

    Authors: Louis P. Cornacchione and Linden T. Hu

    Citation: BMC Microbiology 2020 20:128

    Content type: Research article

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  17. The great metabolic versatility of the purple non-sulfur bacteria is of particular interest in green technology. Rhodospirillum rubrum S1H is an α-proteobacterium that is capable of photoheterotrophic assimilatio...

    Authors: Quentin De Meur, Adam Deutschbauer, Matthias Koch, Guillaume Bayon-Vicente, Paloma Cabecas Segura, Ruddy Wattiez and Baptiste Leroy

    Citation: BMC Microbiology 2020 20:126

    Content type: Research article

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  18. Ferrovum spp. are abundant in acid mine drainage sites globally where they play an important role in biogeochemical cycling. All known taxa in this genus are Fe(II) oxidizers. Thus, co-occurring members of the ge...

    Authors: Christen L. Grettenberger, Jeff R. Havig and Trinity L. Hamilton

    Citation: BMC Microbiology 2020 20:119

    Content type: Research article

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  19. Bacterial gas vesicles, composed of two major gas vesicle proteins and filled with gas, are a unique class of intracellular bubble-like nanostructures. They provide buoyancy for cells, and thus play an essenti...

    Authors: Kun Cai, Bo-Ying Xu, Yong-Liang Jiang, Ying Wang, Yuxing Chen, Cong-Zhao Zhou and Qiong Li

    Citation: BMC Microbiology 2020 20:110

    Content type: Research article

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  20. A broad range of aromatic compounds can be degraded by enteric bacteria, and hydroxyphenylacetic acid (HPA) degrading bacteria are the most widespread. Majority of Escherichia coli strains can use both the struct...

    Authors: Hanseol Kim, Sinyeon Kim, Dohyeon Kim and Sung Ho Yoon

    Citation: BMC Microbiology 2020 20:109

    Content type: Research article

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  21. Lactobacillus species are used as probiotics and play an important role in fermented food production. However, use of 16S rRNA gene sequences as standard markers for the differentiation of Lactobacillus species o...

    Authors: Eiseul Kim, Seung-Min Yang, Bora Lim, Si Hong Park, Bryna Rackerby and Hae-Yeong Kim

    Citation: BMC Microbiology 2020 20:96

    Content type: Research article

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  22. The skin commensal Staphylococcus haemolyticus is an emerging nosocomial pathogen. Despite its clinical relevance, published information about S. haemolyticus virulence factors is scarce. In this study, the adhes...

    Authors: Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim and Jorunn Pauline Cavanagh

    Citation: BMC Microbiology 2020 20:80

    Content type: Research article

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  23. It has been performed worldwidely to explore the potential of animals that might be a reservoir for community associated human infections of Clostridioides difficile. Several genetically undistinguished PCR ribot...

    Authors: Wen-Zhu Zhang, Wen-Ge Li, Yu-Qing Liu, Wen-Peng Gu, Qing Zhang, Hu Li, Zheng-Jie Liu, Xin Zhang, Yuan Wu and Jin-Xing Lu

    Citation: BMC Microbiology 2020 20:70

    Content type: Research article

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  24. The Gram-positive facultative methylotrophic bacterium Bacillus methanolicus uses the sedoheptulose-1,7-bisphosphatase (SBPase) variant of the ribulose monophosphate (RuMP) cycle for growth on the C1 carbon sourc...

    Authors: Johannes Pfeifenschneider, Benno Markert, Jessica Stolzenberger, Trygve Brautaset and Volker F. Wendisch

    Citation: BMC Microbiology 2020 20:63

    Content type: Research article

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  25. Filamentous cyanobacteria represent model organisms for investigating multicellularity. For many species, nitrogen-fixing heterocysts are formed from photosynthetic vegetative cells under nitrogen limitation. ...

    Authors: Julia Walter, Francisco Leganés, Eva-Mari Aro and Peter J. Gollan

    Citation: BMC Microbiology 2020 20:57

    Content type: Research article

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  26. The rice blast is a typical fungal disease caused by Magnaporthe oryzae, and the mitochondrial ATP-dependent Lon protease (MAP1) has been proven to be involved in blast development. We previously screened a C3HC ...

    Authors: Shaoshuai Liu, Yi Wei and Shi-Hong Zhang

    Citation: BMC Microbiology 2020 20:23

    Content type: Research article

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  27. Chlortetracycline (CTC) is one of the commercially important tetracyclines (TCs) family product and is mainly produced by Streptomyces. CTC is still in a great demand due to its broad-spectrum activity against pa...

    Authors: Lingxin Kong, Jia Liu, Xiaoqing Zheng, Zixin Deng and Delin You

    Citation: BMC Microbiology 2019 19:279

    Content type: Research article

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  28. The present study involves diversity and biological activities of the endophytic fungal community from Distylium chinense, a rare waterlogging tolerant plant endemic to the Three Gorges Reservoir. This study h...

    Authors: Xiaoxiang Duan, Fangfang Xu, Dan Qin, Tiancong Gao, Weiyun Shen, Shihao Zuo, Baohong Yu, Jieru Xu, Yajun Peng and Jinyan Dong

    Citation: BMC Microbiology 2019 19:278

    Content type: Research article

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  29. High temperature requirement A (HtrA) is a widely expressed chaperone and serine protease in bacteria. HtrA proteases assemble and hydrolyze misfolded proteins to enhance bacterial survival under stress condit...

    Authors: Carmen M. Abfalter, Sabine Bernegger, Miroslaw Jarzab, Gernot Posselt, Karthe Ponnuraj and Silja Wessler

    Citation: BMC Microbiology 2019 19:255

    Content type: Research article

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  30. Acinetobacter baumannii is one of the most important opportunistic pathogens responsible for hospital acquired infections. It displays multi-drug resistance profile and has the ability to colonize surfaces and pe...

    Authors: Renatas Krasauskas, Jūratė Skerniškytė, Julija Armalytė and Edita Sužiedėlienė

    Citation: BMC Microbiology 2019 19:241

    Content type: Research article

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  31. Streptomyces lividans is an appealing host for the production of proteins of biotechnological interest due to its relaxed exogenous DNA restriction system and its ability to secrete proteins directly to the mediu...

    Authors: Jósé R. Valverde, Sonia Gullón, Clara A. García-Herrero, Iván Campoy and Rafael P. Mellado

    Citation: BMC Microbiology 2019 19:233

    Content type: Software

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  32. Our recent ‘-omics’ comparisons of Streptococcus mutans wild-type and lrgAB-mutant revealed that this organism undergoes dynamic cellular changes in the face of multiple exogenous stresses, consequently affecting...

    Authors: Sang-Joon Ahn, Kamal Deep, Matthew E. Turner, Ivan Ishkov, Anthony Waters, Stephen J. Hagen and Kelly C. Rice

    Citation: BMC Microbiology 2019 19:223

    Content type: Research article

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  33. The molecular characterization of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) isolates is not well studied. Our goal was to investigate the molecular epidemiology of CR-hvKP strains that we...

    Authors: Jun Li, Zi-Yan Huang, Ting Yu, Xiao-Yan Tao, Yong-Mei Hu, Hai-Chen Wang and Ming-Xiang Zou

    Citation: BMC Microbiology 2019 19:219

    Content type: Research article

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  34. The broad-leaved Korean pine mixed forest is an important and typical component of a global temperate forest. Soil microbes are the main driver of biogeochemical cycling in this forest ecosystem and have compl...

    Authors: Minghui Liu, Xin Sui, Yanbo Hu and Fujuan Feng

    Citation: BMC Microbiology 2019 19:218

    Content type: Research article

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  35. The primary and secondary metabolites of fungi are critical for adaptation to environmental stresses, host pathogenicity, competition with other microbes, and reproductive fitness. Drought-derived reactive oxy...

    Authors: Jake C. Fountain, Liming Yang, Manish K. Pandey, Prasad Bajaj, Danny Alexander, Sixue Chen, Robert C. Kemerait, Rajeev K. Varshney and Baozhu Guo

    Citation: BMC Microbiology 2019 19:209

    Content type: Research article

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  36. Tannerella forsythia is a Gram-negative oral pathogen. Together with Porphyromonas gingivalis and Treponema denticola it constitutes the “red complex” of bacteria, which is crucially associated with periodontitis...

    Authors: Valentina M. T. Mayer, Isabel Hottmann, Rudolf Figl, Friedrich Altmann, Christoph Mayer and Christina Schäffer

    Citation: BMC Microbiology 2019 19:200

    Content type: Research article

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  37. It is widely believed that most xenobiotics cross biomembranes by diffusing through the phospholipid bilayer, and that the use of protein transporters is an occasional adjunct. According to an alternative view...

    Authors: Srijan Jindal, Lei Yang, Philip J. Day and Douglas B. Kell

    Citation: BMC Microbiology 2019 19:195

    Content type: Research article

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  38. All living organisms experience physiological changes regulated by endogenous circadian rhythms. The main factor controlling the circadian clock is the duration of daylight. The aim of this research was to ide...

    Authors: Ksenia M. Klimina, Ekaterina G. Batotsyrenova, Roman A. Yunes, Elena H. Gilyaeva, Elena U. Poluektova, Taisia A. Kostrova, Anna V. Kudryavtseva, Maya V. Odorskaya, Vadim A. Kashuro, Artem S. Kasianov, Maksim B. Ivanov and Valery N. Danilenko

    Citation: BMC Microbiology 2019 19:160

    Content type: Research article

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  39. Persisters are rare phenotypic variants within a bacterial population that are capable of tolerating lethal antibiotic concentrations. Passage through stationary phase is associated with the formation of persi...

    Authors: Sandra J. Aedo, Mehmet A. Orman and Mark P. Brynildsen

    Citation: BMC Microbiology 2019 19:140

    Content type: Research article

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  40. In natural environments, bacteria always live in communities with others where their physiological characteristics are influenced by each other. Bacteria can communicate with one another by using autoinducers....

    Authors: Shuxin Zhou, Zixun Yu and Weihua Chu

    Citation: BMC Microbiology 2019 19:135

    Content type: Research article

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  41. Porphyromonas gingivalis is considered a keystone pathogen responsible for chronic periodontitis. Although several virulence factors produced by this bacterium are quite well characterized, very little is known a...

    Authors: Michał Śmiga, Paulina Stępień, Mariusz Olczak and Teresa Olczak

    Citation: BMC Microbiology 2019 19:127

    Content type: Research article

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  42. Riemerella anatipestifer (R. anatipestifer) is one of the most important poultry pathogens worldwide, with associated infections causing significant economic losses. Rifampin Resistance is an important mechanism ...

    Authors: Jiakai Sun, Dekang Zhu, Jinge Xu, Renyong Jia, Shun Chen, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Yunya Liu, Ling Zhang, Yanling Yu, Yu You, Mingshu Wang and Anchun Cheng

    Citation: BMC Microbiology 2019 19:107

    Content type: Research article

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  43. Vitamin B1 (VB1) is a crucial dietary nutrient and essential cofactor for several key enzymes in the regulation of cellular and metabolic processes, and more importantly in the activation of immune system. To dat...

    Authors: Ningning Song, Zhaoli Li, Ziyin Cui, Liping Chen, Yingying Cui, Guanghui Dang, Zhe Li, He Li and Siguo Liu

    Citation: BMC Microbiology 2019 19:104

    Content type: Research article

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  44. Bacterial chemotaxis, the ability of motile bacteria to navigate gradients of chemicals, plays key roles in the establishment of various plant-microbe associations, including those that benefit plant growth an...

    Authors: Mustafa Elmas, Vasilios Alexiades, Lindsey O’Neal and Gladys Alexandre

    Citation: BMC Microbiology 2019 19:101

    Content type: Research article

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  45. Thermotolerance is a highly desirable trait of microbial cell factories and has been the focus of extensive research. Yeast usually tolerate only a narrow temperature range and just two species, Kluyveromyces mar...

    Authors: Mathias Lehnen, Birgitta E. Ebert and Lars M. Blank

    Citation: BMC Microbiology 2019 19:100

    Content type: Research article

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