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Microbe-host interactions and microbial pathogenicity

Section edited by David Nelson

This section aims to publish studies looking at all aspects of microbe-host interactions and pathogenicity including pathogenic mechanisms, virulence factors, host invasion, immune evasion, host defence, immunity, immunology and symbiotic interactions.

Page 9 of 9

  1. Diseases from Staphylococcus aureus are a major problem in Indian hospitals and recent studies point to infiltration of community associated methicillin resistant S. aureus (CA-MRSA) into hospitals. Although CA-M...

    Authors: Srikanth Shambat, Savitha Nadig, Sushma Prabhakara, Michele Bes, Jerome Etienne and Gayathri Arakere

    Citation: BMC Microbiology 2012 12:64

    Content type: Research article

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  2. A powerful approach to understanding complex processes such as aging is to use model organisms amenable to genetic manipulation, and to seek relevant phenotypes to measure. Caenorhabditis elegans is particularly ...

    Authors: Cynthia Portal-Celhay, Ellen R Bradley and Martin J Blaser

    Citation: BMC Microbiology 2012 12:49

    Content type: Research article

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  3. The experimental murine model of leishmaniasis has been widely used to characterize the immune response against Leishmania. CBA mice develop severe lesions, while C57BL/6 present small chronic lesions under L. am...

    Authors: Christian M Probst, Rodrigo A Silva, Juliana P B Menezes, Tais F Almeida, Ivana N Gomes, Andréia C Dallabona, Luiz S Ozaki, Gregory A Buck, Daniela P Pavoni, Marco A Krieger and Patrícia S T Veras

    Citation: BMC Microbiology 2012 12:22

    Content type: Research article

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  4. The production of virulence factors in Staphylococcus aureus is tightly controlled by a complex web of interacting regulators. EsxA is one of the virulence factors that are excreted by the specialized, type VII-l...

    Authors: Bettina Schulthess, Dominik A Bloes and Brigitte Berger-Bächi

    Citation: BMC Microbiology 2012 12:17

    Content type: Research article

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  5. Epithelial cells of the urinary tract recognize pathogenic bacteria through pattern recognition receptors on their surface, such as toll-like receptors (TLRs), and mount an immune response through the activati...

    Authors: Mattias Karlsson, Nikolai Scherbak, Gregor Reid and Jana Jass

    Citation: BMC Microbiology 2012 12:15

    Content type: Research article

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  6. The association between Helicobacter pylori infection and upper gastrointestinal disease is well established. However, only a small fraction of H. pylori carriers develop disease, and there are great geographical...

    Authors: Lars L Eftang, Ying Esbensen, Tone M Tannæs, Ida RK Bukholm and Geir Bukholm

    Citation: BMC Microbiology 2012 12:9

    Content type: Research article

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  7. A common finding amongst patients with inhalational anthrax is a paucity of polymorphonuclear leukocytes (PMNs) in infected tissues in the face of abundant circulating PMNs. A major virulence determinant of an...

    Authors: Chinh Nguyen, Chiguang Feng, Min Zhan, Alan S Cross and Simeon E Goldblum

    Citation: BMC Microbiology 2012 12:2

    Content type: Research article

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  8. Aggregation may play a main role in the adhesion of bacteria to the gastrointestinal epithelium and their colonization ability, as well as in probiotic effects through co-aggregation with intestinal pathogens ...

    Authors: Milan Kojic, Branko Jovcic, Ivana Strahinic, Jelena Begovic, Jelena Lozo, Katarina Veljovic and Ljubisa Topisirovic

    Citation: BMC Microbiology 2011 11:265

    Content type: Research article

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  9. Staphylococcus aureus is a well-armed pathogen prevalent in severe infections such as endocarditis and osteomyelitis. Fibronectin-binding proteins A and B, encoded by fnbA/B, are major pathogenesis determinants i...

    Authors: Jean Philippe Rasigade, Abdelmalek Moulay, Yannick Lhoste, Anne Tristan, Michele Bes, François Vandenesch, Jerome Etienne, Gerard Lina, Frederic Laurent and Oana Dumitrescu

    Citation: BMC Microbiology 2011 11:263

    Content type: Research article

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  10. Candida can cause mucocutaneous and/or systemic infections in hospitalized and immunosuppressed patients. Most individuals are colonized by Candida spp. as part of the oral flora and the intestinal tract. We comp...

    Authors: Juliana C Junqueira, Beth B Fuchs, Maged Muhammed, Jeffrey J Coleman, Jamal MAH Suleiman, Simone FG Vilela, Anna CBP Costa, Vanessa MC Rasteiro, Antonio OC Jorge and Eleftherios Mylonakis

    Citation: BMC Microbiology 2011 11:247

    Content type: Research article

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  11. Streptococcus pneumoniae (the pneumococcus) is the leading cause of otitis media, community-acquired pneumonia (CAP), sepsis, and meningitis. It is now evident that S. pneumoniae forms biofilms during nasopharyng...

    Authors: Carlos J Sanchez, Brady J Hurtgen, Anel Lizcano, Pooja Shivshankar, Garry T Cole and Carlos J Orihuela

    Citation: BMC Microbiology 2011 11:245

    Content type: Research article

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  12. Arcanobacterium haemolyticum is an emerging human pathogen that causes pharyngitis, wound infections, and a variety of occasional invasive diseases. Since its initial discovery in 1946, this Gram positive organis...

    Authors: B Helen Jost, Erynn A Lucas, Stephen J Billington, Adam J Ratner and David J McGee

    Citation: BMC Microbiology 2011 11:239

    Content type: Research article

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  13. Indoor microbial contamination due to excess moisture is an important contributor to human illness in both residential and occupational settings. However, the census of microorganisms in the indoor environment...

    Authors: Miia Pitkäranta, Teija Meklin, Anne Hyvärinen, Aino Nevalainen, Lars Paulin, Petri Auvinen, Ulla Lignell and Helena Rintala

    Citation: BMC Microbiology 2011 11:235

    Content type: Research article

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  14. Filamentous M13 phage extrude from infected Escherichia coli with a tip structure composed of gp7 and gp9. This tip structure is extended by the assembly of the filament composed of the major coat protein gp8. Fi...

    Authors: Martin Ploss and Andreas Kuhn

    Citation: BMC Microbiology 2011 11:211

    Content type: Research article

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    The Erratum to this article has been published in BMC Microbiology 2017 17:180

  15. Haemophilus ducreyi, the causative agent of the sexually transmitted disease chancroid, contains a flp (fimbria like protein) operon that encodes proteins predicted to contribute to adherence and pathogenesis. H....

    Authors: Diane M Janowicz, Sean A Cooney, Jessica Walsh, Beth Baker, Barry P Katz, Kate R Fortney, Beth W Zwickl, Sheila Ellinger and Robert S Munson Jr

    Citation: BMC Microbiology 2011 11:208

    Content type: Research article

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  16. Moraxella catarrhalis, a major nasopharyngeal pathogen of the human respiratory tract, is exposed to rapid downshifts of environmental temperature when humans breathe cold air. It was previously shown that the pr...

    Authors: Violeta Spaniol, Rolf Troller, André Schaller and Christoph Aebi

    Citation: BMC Microbiology 2011 11:182

    Content type: Research article

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  17. A number of studies have revealed that Francisella tularensis (FT) suppresses innate immune responses such as chemokine/cytokine production and neutrophil recruitment in the lungs following pulmonary infection vi...

    Authors: Himangi R Jayakar, Jyothi Parvathareddy, Elizabeth A Fitzpatrick, Xiaowen R Bina, James E Bina, Fabio Re, Felicia D Emery and Mark A Miller

    Citation: BMC Microbiology 2011 11:179

    Content type: Research article

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  18. Recently our group has identified a novel antigen of Mycobacterium tuberculosis, protein PPE44, belonging to the "PPE protein" family. Although its role in infection is largely unknown, PPE44-specific immune resp...

    Authors: Barbara Cuccu, Giulia Freer, Alessandro Genovesi, Carlo Garzelli and Laura Rindi

    Citation: BMC Microbiology 2011 11:167

    Content type: Research article

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  19. The West Nile virus (WNV) nonstructural protein 1 (NS1) is an important antigenic protein that elicits protective antibody responses in animals and can be used for the serological diagnosis of WNV infection. A...

    Authors: En-Cheng Sun, Jian-Nan Ma, Ni-Hong Liu, Tao Yang, Jing Zhao, Hong-Wei Geng, Ling-Feng Wang, Yong-Li Qin, Zhi-Gao Bu, Yin-Hui Yang, Ross A Lunt, Lin-Fa Wang and Dong-Lai Wu

    Citation: BMC Microbiology 2011 11:160

    Content type: Research article

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  20. Foot-and-mouth disease virus (FMDV) uses a highly conserved Arg-Gly-Asp (RGD) triplet for attachment to host cells and this motif is believed to be essential for virus viability. Previous sequence analyses of ...

    Authors: Pinghua Li, Zengjun Lu, Huifang Bao, Dong Li, Donald P King, Pu Sun, Xingwen Bai, Weijun Cao, Simon Gubbins, Yingli Chen, Baoxia Xie, Jianhong Guo, Hong Yin and Zaixin Liu

    Citation: BMC Microbiology 2011 11:154

    Content type: Research article

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  21. Typhimurium is the main serotype of Salmonella enterica subsp. enterica implicated in food-borne diseases worldwide. This study aimed to detect the prevalence of ten markers combined in a macro-array based on mul...

    Authors: Marie Bugarel, Sophie A Granier, François-Xavier Weill, Patrick Fach and Anne Brisabois

    Citation: BMC Microbiology 2011 11:151

    Content type: Research article

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  22. Staphylococcus epidermidis (SE) has emerged as one of the most important causes of nosocomial infections. The SaeRS two-component signal transduction system (TCS) influences virulence and biofilm formation in Sta...

    Authors: Qiang Lou, Tao Zhu, Jian Hu, Haijing Ben, Jinsong Yang, Fangyou Yu, Jingran Liu, Yang Wu, Adrien Fischer, Patrice Francois, Jacques Schrenzel and Di Qu

    Citation: BMC Microbiology 2011 11:146

    Content type: Research article

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  23. Enterohaemorrhagic E. coli (EHEC) can cause severe disease such as bloody diarrhoea and haemolytic uraemic syndrome in humans. Besides production of Shiga toxins, the presence of LEE (eae-gene) and non-LEE (nle) ...

    Authors: Marie Bugarel, Annett Martin, Patrick Fach and Lothar Beutin

    Citation: BMC Microbiology 2011 11:142

    Content type: Research article

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  24. In comparison to other bacterial pathogens, our knowledge of the molecular basis of the pathogenesis of leptospirosis is extremely limited. An improved understanding of leptospiral pathogenetic mechanisms requ...

    Authors: Cláudio Pereira Figueira, Julio Croda, Henry A Choy, David A Haake, Mitermayer G Reis, Albert I Ko and Mathieu Picardeau

    Citation: BMC Microbiology 2011 11:129

    Content type: Research article

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  25. Candida parapsilosis typically is a commensal of human skin. However, when host immune defense is compromised or the normal microflora balance is disrupted, C. parapsilosis transforms itself into an opportunistic...

    Authors: István Nagy, Kata Filkor, Tibor Németh, Zsuzsanna Hamari, Csaba Vágvölgyi and Attila Gácser

    Citation: BMC Microbiology 2011 11:122

    Content type: Research article

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  26. Nearly all Taiwanese H. pylori stains are cagA-genopositive and encode CagA protein. In this study, we evaluated whether different intensity of tyrosine phosphorylated-CagA (p-CagA) had an impact on the clinical ...

    Authors: Chiao-Hsiung Chuang, Hsiao-Bai Yang, Shew-Meei Sheu, Kuei-Hsiang Hung, Jiunn-Jong Wu, Hsiu-Chi Cheng, Wei-Lun Chang and Bor-Shyang Sheu

    Citation: BMC Microbiology 2011 11:121

    Content type: Research article

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  27. The secreted enzyme EndoS, an endoglycosidase from Streptococcus pyogenes, hydrolyzes the N-linked glycan of the constant region of immunoglobulin G (IgG) heavy chain and renders the antibody unable to interact w...

    Authors: Jonathan Sjögren, Cheryl YM Okumura, Mattias Collin, Victor Nizet and Andrew Hollands

    Citation: BMC Microbiology 2011 11:120

    Content type: Research article

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  28. Bacterial adhesive proteins, called adhesins, are frequently the decisive factor in initiation of a bacterial infection. Characterization of such molecules is crucial for the understanding of bacterial pathoge...

    Authors: Riikka Kylväjä, Matti Kankainen, Liisa Holm and Benita Westerlund-Wikström

    Citation: BMC Microbiology 2011 11:117

    Content type: Research article

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  29. Toxoplasma gondii belongs to a large and diverse group of obligate intracellular parasitic protozoa. Primary culture of mice skeletal muscle cells (SkMC) was employed as a model for experimental toxoplasmosis stu...

    Authors: Alessandra F Gomes, Erick V Guimarães, Laís Carvalho, José R Correa, Leila Mendonça-Lima and Helene S Barbosa

    Citation: BMC Microbiology 2011 11:110

    Content type: Research article

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  30. Sinorhizobium meliloti is a symbiotic nitrogen-fixing bacterium that elicits nodules on roots of host plants Medicago sativa. During nodule formation bacteria have to withstand oxygen radicals produced by the pla...

    Authors: Catherine Fontenelle, Carlos Blanco, Morgane Arrieta, Virginie Dufour and Annie Trautwetter

    Citation: BMC Microbiology 2011 11:100

    Content type: Research article

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  31. Salmonella enterica serovar Typhimurium is an intracellular bacterial pathogen which can colonize a variety of hosts, including human, causing syndromes that vary from gastroenteritis and diarrhea to systemic dis...

    Authors: Mariela C Carrica, Patricio O Craig, Víctor A García-Angulo, Andes Aguirre, Eleonora García-Véscovi, Fernando A Goldbaum and Silvio L Cravero

    Citation: BMC Microbiology 2011 11:95

    Content type: Research article

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  32. In order to identify new virulence determinants in Y. pseudotuberculosis a comparison between its genome and that of Yersinia pestis was undertaken. This reveals dozens of pseudogenes in Y. pestis, which are stil...

    Authors: Philippa CR Strong, Stewart J Hinchliffe, Hannah Patrick, Steve Atkinson, Olivia L Champion and Brendan W Wren

    Citation: BMC Microbiology 2011 11:85

    Content type: Research article

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  33. SecDF is an accessory factor of the conserved Sec protein translocation machinery and belongs to the resistance-nodulation-cell division (RND) family of multidrug exporters. SecDF has been shown in Escherichia co...

    Authors: Chantal Quiblier, Annelies S Zinkernagel, Reto A Schuepbach, Brigitte Berger-Bächi and Maria M Senn

    Citation: BMC Microbiology 2011 11:72

    Content type: Research article

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  34. The genome of serotype M28 group A Streptococcus (GAS) strain MGAS6180 contains a novel genetic element named Region of Difference 2 (RD2) that encodes seven putative secreted extracellular proteins. RD2 is prese...

    Authors: Izabela Sitkiewicz, Nicole M Green, Nina Guo, Laurent Mereghetti and James M Musser

    Citation: BMC Microbiology 2011 11:65

    Content type: Research article

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  35. Pasteurella pneumotropica is a ubiquitous bacterium that is frequently isolated from laboratory rodents and causes various clinical symptoms in immunodeficient animals. Currently two RTX toxins, PnxIA and PnxIIA,...

    Authors: Hiraku Sasaki, Hiroki Ishikawa, Toru Sato, Satoshi Sekiguchi, Hiromi Amao, Eiichi Kawamoto, Tetsuya Matsumoto and Kazuhiko Shirama

    Citation: BMC Microbiology 2011 11:55

    Content type: Research article

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  36. Klebsiella pneumoniae displaying the hypermucoviscosity (HV) phenotype are considered more virulent than HV-negative strains. Nevertheless, the emergence of tissue-abscesses-associated HV-negative isolates motiva...

    Authors: Yi-Chun Lin, Min-Chi Lu, Hui-Ling Tang, Hsu-Chung Liu, Ching-Hsien Chen, Keh-Sen Liu, Chingju Lin, Chien-Shun Chiou, Ming-Ko Chiang, Chuan-Mu Chen and Yi-Chyi Lai

    Citation: BMC Microbiology 2011 11:50

    Content type: Research article

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  37. Streptococcus suis is a major swine pathogen worldwide that causes meningitis, septicemia, arthritis, and endocarditis. Using animal models, a surface-associated subtilisin-like protease (SspA) has recently been ...

    Authors: Laetitia Bonifait and Daniel Grenier

    Citation: BMC Microbiology 2011 11:47

    Content type: Research article

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  38. During inhalational anthrax, internalization of Bacillus anthracis spores by host cells within the lung is believed to be a key step for initiating the transition from the localized to disseminated stages of infe...

    Authors: Ian M Gut, Batcha Tamilselvam, Angela M Prouty, Bojana Stojkovic, Stephanie Czeschin, Wilfred A van der Donk and Steven R Blanke

    Citation: BMC Microbiology 2011 11:46

    Content type: Research article

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  39. Puumala virus, the agent of nephropathia epidemica (NE), is the most prevalent hantavirus in Europe. The risk for human infection seems to be strongly correlated with the prevalence of Puumala virus (PUUV) in ...

    Authors: Alexis Ribas Salvador, Emmanuel Guivier, Anne Xuéreb, Yannick Chaval, Patrice Cadet, Marie-Lazarine Poulle, Tarja Sironen, Liina Voutilainen, Heikki Henttonen, Jean-François Cosson and Nathalie Charbonnel

    Citation: BMC Microbiology 2011 11:30

    Content type: Research article

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  40. Bacterial exported proteins represent key components of the host-pathogen interplay. Hence, we sought to implement a combined approach for characterizing the entire exoproteome of the pathogenic bacterium Coryneb...

    Authors: Luis GC Pacheco, Susan E Slade, Núbia Seyffert, Anderson R Santos, Thiago LP Castro, Wanderson M Silva, Agenor V Santos, Simone G Santos, Luiz M Farias, Maria AR Carvalho, Adriano MC Pimenta, Roberto Meyer, Artur Silva, James H Scrivens, Sérgio C Oliveira, Anderson Miyoshi…

    Citation: BMC Microbiology 2011 11:12

    Content type: Research article

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  41. Burkholderia pseudomallei is the causative agent of melioidosis, a tropical disease of humans with a variable and often fatal outcome. In murine models of infection, different strains exhibit varying degrees of v...

    Authors: Matthew E Wand, Claudia M Müller, Richard W Titball and Stephen L Michell

    Citation: BMC Microbiology 2011 11:11

    Content type: Research article

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