Clinical microbiology and vaccines

Section edited by Igor Mokrousov and Raffaele Zarrilli

This section aims to publish studies looking at all aspects of clinical microbiology, including virology, epidemiology, antimicrobial resistance, vaccines and immune responses.

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  1. Research article

    Re-classification within the serogroups O3 and O8 of Citrobacter strains

    Citrobacter strains are opportunistic pathogens often responsible for serious enteric as well as extra-intestinal diseases, and therefore the O-antigenic scheme, still in use in diagno...

    Ewa Katzenellenbogen, Magdalena Staniszewska, Nina A. Kocharova, Małgorzata Mieszała, Agnieszka Korzeniowska-Kowal, Sabina Górska, Yuriy A. Knirel and Andrzej Gamian

    BMC Microbiology 2017 17:169

    Published on: 27 July 2017

    The Erratum to this article has been published in BMC Microbiology 2017 17:173

  2. Research article

    Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo

    Cationic antibacterial peptides (CAPs) and synthetic molecules mimicking the amphiphilic structure of CAPs, such as ceragenins, are promising compounds for the development of new antimicrobials.

    Bonita Durnaś, Ewelina Piktel, Marzena Wątek, Tomasz Wollny, Stanisław Góźdź, Jolanta Smok-Kalwat, Katarzyna Niemirowicz, Paul B. Savage and Robert Bucki

    BMC Microbiology 2017 17:167

    Published on: 26 July 2017

  3. Research article

    Acid tolerance properties of dental biofilms in vivo

    The ecological plaque hypothesis explains caries development as the result of the enrichment of acid tolerant bacteria in dental biofilms in response to prolonged periods of low pH. Acid production by an acid ...

    A Senneby, JR Davies, G Svensäter and J Neilands

    BMC Microbiology 2017 17:165

    Published on: 25 July 2017

  4. Methodology Article

    Improved detection of genus-specific Alphavirus using a generic TaqMan® assay

    Alphaviruses are arthropod borne RNA viruses of medical importance. Geographical expansion of mosquitoes of the Aedes genus in the past decades has been associated with major Alphavirus-associated outbreaks. Clim...

    Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque and Marie-Christine Jaffar-Bandjee

    BMC Microbiology 2017 17:164

    Published on: 24 July 2017

  5. Research article

    Comparison of biomarker based Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and conventional methods in the identification of clinically relevant bacteria and yeast

    MALDI-TOF MS is an analytical method that has recently become integral in the identification of microorganisms in clinical laboratories. It relies on databases that majorly employ pattern recognition or finger...

    Ali Kassim, Valentin Pflüger, Zul Premji, Claudia Daubenberger and Gunturu Revathi

    BMC Microbiology 2017 17:128

    Published on: 25 May 2017

  6. Methodology Article

    Identification and quantification of virulence factors of enterotoxigenic Escherichia coli by high-resolution melting curve quantitative PCR

    Diagnosis of enterotoxigenic E. coli (ETEC) associated diarrhea is complicated by the diversity of E.coli virulence factors. This study developed a multiplex quantitative PCR assay based on high-resolution meltin...

    Weilan Wang, Ruurd T. Zijlstra and Michael G. Gänzle

    BMC Microbiology 2017 17:114

    Published on: 15 May 2017

  7. Research article

    FilmArray™ GI panel performance for the diagnosis of acute gastroenteritis or hemorragic diarrhea

    Acute gastroenteritis is a common cause of morbidity and mortality in humans worldwide. The rapid and specific identification of infectious agents is crucial for correct patient management. However, diagnosis ...

    Antonio Piralla, Giovanna Lunghi, Gianluigi Ardissino, Alessia Girello, Marta Premoli, Erika Bava, Milena Arghittu, Maria Rosaria Colombo, Alessandra Cognetto, Patrizia Bono, Giulia Campanini, Piero Marone and Fausto Baldanti

    BMC Microbiology 2017 17:111

    Published on: 12 May 2017

  8. Research article

    Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma

    This study of the oropharyngeal microbiome complements the previously published AZIthromycin in Severe ASThma (AZISAST) clinical trial, where the use of azithromycin was assessed in subjects with exacerbation-...

    Guido Lopes dos Santos Santiago, Guy Brusselle, Kenny Dauwe, Pieter Deschaght, Chris Verhofstede, Dries Vaneechoutte, Ellen Deschepper, Paul Jordens, Guy Joos and Mario Vaneechoutte

    BMC Microbiology 2017 17:109

    Published on: 10 May 2017

  9. Methodology Article

    Simultaneous detection of chikungunya virus, dengue virus and human pathogenic Leptospira genomes using a multiplex TaqMan® assay

    In 2005–2006 a major epidemics of Chikungunya disease occurred in South-West Indian Ocean islands. In Reunion Island, the magnitude of Chikungunya infection related symptoms was high and with over 38% of serol...

    Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque and Marie-Christine Jaffar-Bandjee

    BMC Microbiology 2017 17:105

    Published on: 3 May 2017

  10. Researc article

    Nationwide molecular epidemiology of methicillin-resistant Staphylococcus aureus responsible for horse infections in France

    The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) isolated in horse infections is not well documented, especially in France. The aim of the study was to evaluate the prevalence of MRSA isolat...

    François Guérin, Marguerite Fines-Guyon, Pierrick Meignen, Géraldine Delente, Caroline Fondrinier, Nancy Bourdon, Vincent Cattoir and Albertine Léon

    BMC Microbiology 2017 17:104

    Published on: 3 May 2017

  11. Methodology Article

    Ribosomal subunit protein typing using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the identification and discrimination of Aspergillus species

    Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is genera...

    Sayaka Nakamura, Hiroaki Sato, Reiko Tanaka, Yoko Kusuya, Hiroki Takahashi and Takashi Yaguchi

    BMC Microbiology 2017 17:100

    Published on: 26 April 2017

  12. Research article

    Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas

    Campylobacteriosis is a dominant bacterial cause of foodborne infection and is considered the main public health problem in Europe and many other countries worldwide. In the study lasting from 2011 to 2013 we ...

    Bernadeta Szczepanska, Małgorzata Andrzejewska, Dorota Spica and Jacek J. Klawe

    BMC Microbiology 2017 17:80

    Published on: 4 April 2017

  13. Methodology article

    Comparison of stool versus rectal swab samples and storage conditions on bacterial community profiles

    Sample collection for gut microbiota analysis from in-patients can be challenging. Collection method and storage conditions are potential sources of variability. In this study, we compared the bacterial microb...

    Christine M. Bassis, Nicholas M. Moore, Karen Lolans, Anna M. Seekatz, Robert A. Weinstein, Vincent B. Young and Mary K. Hayden

    BMC Microbiology 2017 17:78

    Published on: 31 March 2017

  14. Research article

    Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control

    Mass drug administration (MDA) with azithromycin is a corner-stone of trachoma control however it may drive the emergence of antimicrobial resistance. In a cluster-randomized trial (Clinical trial gov NCT00792...

    Ebrima Bojang, James Jafali, Vincent Perreten, John Hart, Emma M. Harding-Esch, Ansumana Sillah, David C. W. Mabey, Martin J. Holland, Robin L. Bailey, Anna Roca and Sarah E. Burr

    BMC Microbiology 2017 17:75

    Published on: 28 March 2017

  15. Research article

    Clonality, outer-membrane proteins profile and efflux pump in KPC- producing Enterobacter sp. in Brazil

    Carbapenems resistance in Enterobacter spp. has increased in the last decade, few studies, however, described the mechanisms of resistance in this bacterium. This study evaluated clonality and mechanisms of carba...

    Juliana Ferraz Rosa, Camila Rizek, Ana Paula Marchi, Thais Guimaraes, Lourdes Miranda, Claudia Carrilho, Anna S Levin and Silvia F Costa

    BMC Microbiology 2017 17:69

    Published on: 17 March 2017

  16. Research article

    Molecular characterization of invasive capsule null Neisseria meningitidis in South Africa

    The meningococcal capsule is an important virulence determinant. Unencapsulated meningococci lacking capsule biosynthesis genes and containing the capsule null locus (cnl) are predominantly non-pathogenic. Rare c...

    Karistha Ganesh, Mushal Allam, Nicole Wolter, Holly B. Bratcher, Odile B. Harrison, Jay Lucidarme, Ray Borrow, Linda de Gouveia, Susan Meiring, Monica Birkhead, Martin C. J. Maiden, Anne von Gottberg and Mignon du Plessis

    BMC Microbiology 2017 17:40

    Published on: 21 February 2017

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