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Clinical microbiology and vaccines

Section edited by Igor Mokrousov and Raffaele Zarrilli

This section aims to publish studies looking at all aspects of clinical microbiology, including virology, epidemiology, antimicrobial resistance, vaccines and immune responses.

Page 1 of 6

  1. Content type: Research article

    The effects of gut microbiota on human traits are expected to be small to moderate and adding the complexity of the human diseases, microbiome research demands big sample sizes. Fecal samples for such studies ...

    Authors: Joanna W. Szopinska, Raphaële Gresse, Saskia van der Marel, Jos Boekhorst, Sabina Lukovac, Iris van Swam, Barbara Franke, Harro Timmerman, Clara Belzer and Alejandro Arias Vasquez

    Citation: BMC Microbiology 2018 18:110

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  2. Content type: Research article

    Hypervirulent Klebsiella pneumoniae (hvKP) is emerging around the Asian-Pacific region and it is the major cause of the community-acquired pyogenic liver abscesses. Multidrug-resistant hypervirulent Klebsiella pn...

    Authors: Qiucheng Shi, Peng Lan, Danyan Huang, Xiaoting Hua, Yan Jiang, Jiancang Zhou and Yunsong Yu

    Citation: BMC Microbiology 2018 18:94

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  3. Content type: Research article

    Chronic Lung Allograft Dysfunction (CLAD) is the main cause of morbidity and mortality after the first year following lung transplantation (LTx). Risk factors of CLAD have been extensively studied, but the ass...

    Authors: Sarah Orfanos, Carine Gomez, Sophie Baron, Ritesh Akkisetty, Nadine Dufeu, Bérengère Coltey, Pascal Alexandre Thomas, Jean Marc Rolain and Martine Reynaud-Gaubert

    Citation: BMC Microbiology 2018 18:88

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  4. Content type: Research article

    Gold nanoparticles (AuNP) have several biochemical advantageous properties especially for a candidate of drug carrier. However, the non-conjugated AuNP has a higher rate of cellular uptake than the conjugated ...

    Authors: Sujittra Taratummarat, Naunpun Sangphech, Chau Tran Bao Vu, Tanapat Palaga, Thunnicha Ondee, Saowapha Surawut, Amornpun Sereemaspun, Patcharee Ritprajak and Asada Leelahavanichkul

    Citation: BMC Microbiology 2018 18:85

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  5. Content type: Research

    Sepsis refers to clinical presentations ranging from mild body dysfunction to multiple organ failure. These clinical symptoms result from a systemic inflammatory response to pathogenic or potentially pathogeni...

    Authors: Monica Martins Pereira Faria, Brent Warren Winston, Michael Gordon Surette and John Maynard Conly

    Citation: BMC Microbiology 2018 18:79

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  6. Content type: Research article

    Moraxella catarrhalis (M. catarrhalis) is an important bacterial pathogen. However, its antibiotic susceptibility patterns in different areas are difficult to compare because of the use of different methods and j...

    Authors: Wei Shi, Denian Wen, Changhui Chen, Lin Yuan, Wei Gao, Ping Tang, Xiaoping Cheng and Kaihu Yao

    Citation: BMC Microbiology 2018 18:77

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  7. Content type: Research article

    Salmonella vaccination is one of the control measure that farmers can use to reduce bacterial shedding in their flocks. This study aimed to examine the efficacy of the Vaxsafe® ST (Strain STM-1) attenuated live v...

    Authors: Pardeep Sharma, Charles Caraguel, Margaret Sexton, Andrea McWhorter, Greg Underwood, Karen Holden and Kapil Chousalkar

    Citation: BMC Microbiology 2018 18:78

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  8. Content type: Research article

    Shiga toxin producing E. coli (STEC) is an emerging zoonotic pathogen that can cause acute renal failure, especially in children. Clinical microbiology laboratories may fail to detect STEC and other diarrhoeic E....

    Authors: John Bosco Kalule, Karen H. Keddy and Mark P. Nicol

    Citation: BMC Microbiology 2018 18:55

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  9. Content type: Research article

    Identification and characterization of non-typeable Haemophilus influenzae (NTHi) with reduced susceptibility to β-lactam antibiotics due to mutations in penicillin binding protein 3 (PBP3) is a clinical challeng...

    Authors: John Thegerström, Erika Matuschek, Yu-Ching Su, Kristian Riesbeck and Fredrik Resman

    Citation: BMC Microbiology 2018 18:48

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  10. Content type: Research article

    Antimicrobial resistant Coagulase-negative Staphylococci (CoNS) have limited treatment options, rendered diseases untreatable and made hospitals to be reservoirs of the resistant strains. The aim of this study...

    Authors: Serawit Deyno, Sintayehu Fekadu and Sisay Seyfe

    Citation: BMC Microbiology 2018 18:43

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  11. Content type: Research article

    Carbapenemases-producing Enterobacteriaceae (CPE) are a worldwide public health emergency. In Mexico, reports of CPE are limited, particularly in the pediatric population. Here, we describe the clinical, epide...

    Authors: Alejandra Aquino-Andrade, Jocelin Merida-Vieyra, Eduardo Arias de la Garza, Patricia Arzate-Barbosa and Agustín De Colsa Ranero

    Citation: BMC Microbiology 2018 18:38

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  12. Content type: Research article

    During the past decades, Streptococcus dysgalactiae subspecies equisimilis (SDSE) has been increasingly recognized as an important human pathogen. Osteoarticular infections is one of the predominant disease manif...

    Authors: Oddvar Oppegaard, Haima Mylvaganam, Steinar Skrede and Bård Reiakvam Kittang

    Citation: BMC Microbiology 2018 18:17

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  13. Content type: Research article

    Two-thirds of the world’s population is thought to be infected by Helicobacter pylori. Although most people infected with H. pylori are asymptomatic, this pathogen is associated with several gastric pathologies i...

    Authors: Phattharaphon Wongphutorn, Chariya Chomvarin, Banchob Sripa, Wises Namwat and Kiatichai Faksri

    Citation: BMC Microbiology 2018 18:10

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  14. Content type: Research article

    Hypervirulent K. pneumoniae (hvKp) causes severe community acquired infections, predominantly in Asia. Though initially isolated from liver abscesses, they are now prevalent among invasive infections such as bact...

    Authors: Chaitra Shankar, Balaji Veeraraghavan, Laura Eve Buchnan Nabarro, Raji Ravi, Naveen Kumar Devanga Ragupathi and Priscilla Rupali

    Citation: BMC Microbiology 2018 18:6

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  15. Content type: Research article

    Blastocystis sp. is a unicellular eukaryote that is commonly found in the human intestine. Its ability to cause disease is debated and a subject for ongoing research. In this study, fa...

    Authors: Joakim Forsell, Johan Bengtsson-Palme, Martin Angelin, Anders Johansson, Birgitta Evengård and Margareta Granlund

    Citation: BMC Microbiology 2017 17:231

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  16. Content type: Research article

    Multi-drug resistant bacteria are a phenomenon which is on the increase around the world, particularly with the emergence of colistin-resistant Enterobacteriaceae and vancomycin-resistant enterococci strains. The...

    Authors: Lucie Bardet, Stéphanie Le Page, Thongpan Leangapichart and Jean-Marc Rolain

    Citation: BMC Microbiology 2017 17:220

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  17. Content type: Research article

    Porcine circovirus type 2 (PCV2) remains the main causative viral pathogen of porcine circovirus-associated diseases (PCVAD) of great economic importance in pig industry globally. This...

    Authors: Kayode Olayinka Afolabi, Benson Chuks Iweriebor, Larry Chikwelu Obi and Anthony Ifeanyi Okoh

    Citation: BMC Microbiology 2017 17:212

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  18. Content type: Research article

    Dysbiosis of gut microbiota are commonly reported in autism spectrum disorder (ASD) and may contribute to behavioral impairment. Vitamin A (VA) plays a role in regulation of gut microbiota. This study was perf...

    Authors: Juan Liu, Xiao Liu, Xue-Qin Xiong, Ting Yang, Ting Cui, Na-Li Hou, Xi Lai, Shu Liu, Min Guo, Xiao-Hua Liang, Qian Cheng, Jie Chen and Ting-Yu Li

    Citation: BMC Microbiology 2017 17:204

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  19. Content type: Methodology Article

    Urinary tract infection (UTI) is one of the most common diagnoses in girls and women, and to a lesser extent in boys and men younger than 50 years. Escherichia coli, followed by Klebsiella spp. and Proteus spp., ...

    Authors: Milena Lussu, Tania Camboni, Cristina Piras, Corrado Serra, Francesco Del Carratore, Julian Griffin, Luigi Atzori and Aldo Manzin

    Citation: BMC Microbiology 2017 17:201

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  20. Content type: Methodology Article

    Outbreaks of Kingella kingae infection are an emerging public health concern among daycare attendees carrying epidemic clones in the oropharynx. However, genotyping of such epidemic clones from affected cases is ...

    Authors: Nawal El Houmami, Janek Bzdrenga, Jean-Christophe Pons, Philippe Minodier, Guillaume André Durand, Anis Oubraham, Dimitri Ceroni, Pablo Yagupsky, Didier Raoult, Philippe Bidet and Pierre-Edouard Fournier

    Citation: BMC Microbiology 2017 17:200

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  21. Content type: Research article

    Citrobacter strains are opportunistic pathogens often responsible for serious enteric as well as extra-intestinal diseases, and therefore the O-antigenic scheme, still in use in diagno...

    Authors: Ewa Katzenellenbogen, Magdalena Staniszewska, Nina A. Kocharova, Małgorzata Mieszała, Agnieszka Korzeniowska-Kowal, Sabina Górska, Yuriy A. Knirel and Andrzej Gamian

    Citation: BMC Microbiology 2017 17:169

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    The Erratum to this article has been published in BMC Microbiology 2017 17:173

  22. Content type: Research article

    Cationic antibacterial peptides (CAPs) and synthetic molecules mimicking the amphiphilic structure of CAPs, such as ceragenins, are promising compounds for the development of new antimicrobials.

    Authors: Bonita Durnaś, Ewelina Piktel, Marzena Wątek, Tomasz Wollny, Stanisław Góźdź, Jolanta Smok-Kalwat, Katarzyna Niemirowicz, Paul B. Savage and Robert Bucki

    Citation: BMC Microbiology 2017 17:167

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  23. Content type: Research article

    The ecological plaque hypothesis explains caries development as the result of the enrichment of acid tolerant bacteria in dental biofilms in response to prolonged periods of low pH. Acid production by an acid ...

    Authors: A Senneby, JR Davies, G Svensäter and J Neilands

    Citation: BMC Microbiology 2017 17:165

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  24. Content type: Methodology Article

    Alphaviruses are arthropod borne RNA viruses of medical importance. Geographical expansion of mosquitoes of the Aedes genus in the past decades has been associated with major Alphavirus-associated outbreaks. Clim...

    Authors: Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque and Marie-Christine Jaffar-Bandjee

    Citation: BMC Microbiology 2017 17:164

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  25. Content type: Research article

    MALDI-TOF MS is an analytical method that has recently become integral in the identification of microorganisms in clinical laboratories. It relies on databases that majorly employ pattern recognition or finger...

    Authors: Ali Kassim, Valentin Pflüger, Zul Premji, Claudia Daubenberger and Gunturu Revathi

    Citation: BMC Microbiology 2017 17:128

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  26. Content type: Methodology Article

    Diagnosis of enterotoxigenic E. coli (ETEC) associated diarrhea is complicated by the diversity of E.coli virulence factors. This study developed a multiplex quantitative PCR assay based on high-resolution meltin...

    Authors: Weilan Wang, Ruurd T. Zijlstra and Michael G. Gänzle

    Citation: BMC Microbiology 2017 17:114

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  27. Content type: Research article

    Acute gastroenteritis is a common cause of morbidity and mortality in humans worldwide. The rapid and specific identification of infectious agents is crucial for correct patient management. However, diagnosis ...

    Authors: Antonio Piralla, Giovanna Lunghi, Gianluigi Ardissino, Alessia Girello, Marta Premoli, Erika Bava, Milena Arghittu, Maria Rosaria Colombo, Alessandra Cognetto, Patrizia Bono, Giulia Campanini, Piero Marone and Fausto Baldanti

    Citation: BMC Microbiology 2017 17:111

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  28. Content type: Research article

    This study of the oropharyngeal microbiome complements the previously published AZIthromycin in Severe ASThma (AZISAST) clinical trial, where the use of azithromycin was assessed in subjects with exacerbation-...

    Authors: Guido Lopes dos Santos Santiago, Guy Brusselle, Kenny Dauwe, Pieter Deschaght, Chris Verhofstede, Dries Vaneechoutte, Ellen Deschepper, Paul Jordens, Guy Joos and Mario Vaneechoutte

    Citation: BMC Microbiology 2017 17:109

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  29. Content type: Methodology Article

    In 2005–2006 a major epidemics of Chikungunya disease occurred in South-West Indian Ocean islands. In Reunion Island, the magnitude of Chikungunya infection related symptoms was high and with over 38% of serol...

    Authors: Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque and Marie-Christine Jaffar-Bandjee

    Citation: BMC Microbiology 2017 17:105

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  30. Content type: Researc article

    The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) isolated in horse infections is not well documented, especially in France. The aim of the study was to evaluate the prevalence of MRSA isolat...

    Authors: François Guérin, Marguerite Fines-Guyon, Pierrick Meignen, Géraldine Delente, Caroline Fondrinier, Nancy Bourdon, Vincent Cattoir and Albertine Léon

    Citation: BMC Microbiology 2017 17:104

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  31. Content type: Methodology Article

    Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is genera...

    Authors: Sayaka Nakamura, Hiroaki Sato, Reiko Tanaka, Yoko Kusuya, Hiroki Takahashi and Takashi Yaguchi

    Citation: BMC Microbiology 2017 17:100

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  32. Content type: Research article

    Campylobacteriosis is a dominant bacterial cause of foodborne infection and is considered the main public health problem in Europe and many other countries worldwide. In the study lasting from 2011 to 2013 we ...

    Authors: Bernadeta Szczepanska, Małgorzata Andrzejewska, Dorota Spica and Jacek J. Klawe

    Citation: BMC Microbiology 2017 17:80

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  33. Content type: Methodology article

    Sample collection for gut microbiota analysis from in-patients can be challenging. Collection method and storage conditions are potential sources of variability. In this study, we compared the bacterial microb...

    Authors: Christine M. Bassis, Nicholas M. Moore, Karen Lolans, Anna M. Seekatz, Robert A. Weinstein, Vincent B. Young and Mary K. Hayden

    Citation: BMC Microbiology 2017 17:78

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  34. Content type: Research article

    Mass drug administration (MDA) with azithromycin is a corner-stone of trachoma control however it may drive the emergence of antimicrobial resistance. In a cluster-randomized trial (Clinical trial gov NCT00792...

    Authors: Ebrima Bojang, James Jafali, Vincent Perreten, John Hart, Emma M. Harding-Esch, Ansumana Sillah, David C. W. Mabey, Martin J. Holland, Robin L. Bailey, Anna Roca and Sarah E. Burr

    Citation: BMC Microbiology 2017 17:75

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  35. Content type: Research article

    Carbapenems resistance in Enterobacter spp. has increased in the last decade, few studies, however, described the mechanisms of resistance in this bacterium. This study evaluated clonality and mechanisms of carba...

    Authors: Juliana Ferraz Rosa, Camila Rizek, Ana Paula Marchi, Thais Guimaraes, Lourdes Miranda, Claudia Carrilho, Anna S Levin and Silvia F Costa

    Citation: BMC Microbiology 2017 17:69

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  36. Content type: Research article

    After E. coli O157, E. coli O26 is the second most prevalent enterohaemorrhagic E. coli (EHEC) serotype identified in cases of foodborne illness in Australia and throughout the world. E. coli O26 associated foodb...

    Authors: Salma A. Lajhar, Jeremy Brownlie and Robert Barlow

    Citation: BMC Microbiology 2017 17:47

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  37. Content type: Research article

    The meningococcal capsule is an important virulence determinant. Unencapsulated meningococci lacking capsule biosynthesis genes and containing the capsule null locus (cnl) are predominantly non-pathogenic. Rare c...

    Authors: Karistha Ganesh, Mushal Allam, Nicole Wolter, Holly B. Bratcher, Odile B. Harrison, Jay Lucidarme, Ray Borrow, Linda de Gouveia, Susan Meiring, Monica Birkhead, Martin C. J. Maiden, Anne von Gottberg and Mignon du Plessis

    Citation: BMC Microbiology 2017 17:40

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  38. Content type: Research article

    Pseudomonas aeruginosa typically displays loss of virulence-associated secretions over the course of chronic cystic fibrosis infections. This has led to the suggestion that virulence i...

    Authors: Siobhán O’Brien, David Williams, Joanne L. Fothergill, Steve Paterson, Craig Winstanley and Michael A. Brockhurst

    Citation: BMC Microbiology 2017 17:30

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  39. Content type: Research article

    The bronchial microbiome in chronic lung diseases presents an abnormal pattern, but its microbial composition and regional differences in severe asthma have not been sufficiently addressed. The aim of the stud...

    Authors: Laura Millares, Guadalupe Bermudo, Vicente Pérez-Brocal, Christian Domingo, Marian Garcia-Nuñez, Xavier Pomares, Andrés Moya and Eduard Monsó

    Citation: BMC Microbiology 2017 17:20

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  40. Content type: Research article

    Bovine enterovirus (BEV) belongs to the species Enterovirus E or F, genus Enterovirus and family Picornaviridae. Although numerous studies have identified BEVs in the feces of cattle with diarrhea, the pathogenic...

    Authors: Shinobu Tsuchiaka, Sayed Samim Rahpaya, Konosuke Otomaru, Hiroshi Aoki, Mai Kishimoto, Yuki Naoi, Tsutomu Omatsu, Kaori Sano, Sachiko Okazaki-Terashima, Yukie Katayama, Mami Oba, Makoto Nagai and Tetsuya Mizutani

    Citation: BMC Microbiology 2017 17:18

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  41. Content type: Researc article

    Ticks transmit Babesia microti, the causative agents of babesiosis in North America and Europe. Babesiosis is now endemic in Northeastern USA and affects people of all ages. Babesia species infect erythrocytes an...

    Authors: Lavoisier Akoolo, Samantha Schlachter, Rasel Khan, Laura Alter, Albert D. Rojtman, Kristine Gedroic, Purnima Bhanot and Nikhat Parveen

    Citation: BMC Microbiology 2017 17:16

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  42. Content type: Research article

    Staphylococcus epidermidis is an opportunistic pathogen involved in hospital-acquired infections, particularly in those related to medical devices. This study characterized 50 genetica...

    Authors: Vivian Carolina Salgueiro, Natalia Lopes Pontes Iorio, Marcelle Cristina Ferreira, Raiane Cardoso Chamon and Kátia Regina Netto dos Santos

    Citation: BMC Microbiology 2017 17:15

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  43. Content type: Methodology article

    Scrub typhus is a mite-borne rickettsiosis caused by infection of Orientia tsutsugamushi, which is endemic to several Asia-Pacific Rim countries, including Japan. Although micro-indirect immunofluorescent assay (...

    Authors: Motohiko Ogawa, Masaaki Satoh, Masayuki Saijo and Shuji Ando

    Citation: BMC Microbiology 2017 17:7

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  44. Content type: Research article

    The prevalence of Helicobacter pylori antibiotic susceptibility in the Nepalese strains is untracked. We determined the antibiotic susceptibility for H. pylori and analyzed the presence of genetic mutations assoc...

    Authors: Muhammad Miftahussurur, Pradeep Krishna Shrestha, Phawinee Subsomwong, Rabi Prakash Sharma and Yoshio Yamaoka

    Citation: BMC Microbiology 2016 16:256

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