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Table 1 Effect of L-PA on excretion parameters and intestinal motility in constipated mice

From: Protective effect of L-pipecolic acid on constipation in C57BL/6 mice based on gut microbiome and serum metabolomic

 

Con group

Lop group

Lop + L-PA group

P

Stool pellet number (ea)

7.8 ± 2.6

8 ± 4.1

10.5 ± 2.9

0.2943

Fecal water content (%)

60.5 ± 5.9

47.4 ± 4.3**

55.1 ± 5.7#

0.0025

First black stool defecation time (min)

168.5 ± 76

272 ± 38.1*

157 ± 37.8##

0.0036

Intestinal transit rate (%)

88.3 ± 9.4

69 ± 6.8**

91.7 ± 8.8##

0.0006