Fig. 1From: Protective effect of L-pipecolic acid on constipation in C57BL/6 mice based on gut microbiome and serum metabolomicAlteration of gut microbiome. The common and unique OTUs of gut flora were shown in a Venn map between healthy controls and children with FC (A). The abundance of species at the phylum level (B). A chao1 (C) metric and an ace metric (D) were used to assess the α diversity. β diversity index was significantly lower in the functional constipation group compared with the control group (E). The altered microbiome was processed by STAMP analysis (F)Back to article page