Table 3 Gene expressions fold change before and after treatment of E. coli isolates with vitamin C
From: Antibacterial effect of vitamin C against uropathogenic E. coli in vitro and in vivo
Gene | Before vitamin C treatment Median (IQR) | After vitamin C treatment Median (IQR) | P-value |
|---|---|---|---|
blaSHV | 986.8 (699.1–12,284.4) | 259.5 (85.6–877.7) | 0.005* |
blaTEM | 127.5 (101.1–183.1) | 20.7 (11.5–68.6) | 0.003* |
blaCTX-M | 115.9 (82.7–191.6) | 32.7 (11.2–64.1) | 0.012* |
BlaVIM | 1107.4 (814.8–2269.4) | 1023.3 (755–1813.1) | 0.059 |
blaNDM | 70.1 (48.2–125.1) | 14.4 (5.7–30.2) | 0.007* |
blaIMP | 100.8 (80.4–207) | 9.4 (3.8–24.3) | 0.005* |
LasR | 1377.6 (269.1–5762.5) | 359.4 (170.4–575.7) | 0.028* |
LecA | 3381.3 (1395.8–8169.8) | 202.7 (87–2514.9) | 0.013* |
PelA | 4480.9 (398–6655.8) | 2283.8 (849.7–4755.2) | 0.333 |