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Table 1 The composition of niosomal formulations

From: Surfactant nanovesicles for augmented antibacterial activity against carbapenemase resistant enterobacteriaceae and extended spectrum beta-lactamases producing bacteria: in vitro and in vivo evaluation

Code

Composition

*Weight ratio (gm)

Size(nm)

F1

S:CH: L

4:1:1.25

129.7 (± 30.5)

F2

S:CH: L:SA

4:1:1.25:0.3

171.3 (± 11.56)

  1. S is Span 60, CH is cholesterol, L is lecithin and SA is stearyl amine. Ethanol (5ml) was added, and the lipids were hydrated to a final volume of 100 ml with water and drug concentration was 3 mg/ml