Skip to main content
Fig. 5 | BMC Microbiology

Fig. 5

From: Controlling taxa abundance improves metatranscriptomics differential analysis

Fig. 5

IBDMDB data analysis. A Reproducibility analysis. x-axis shows the number of top differential features. y-axis shows the number of top differential features identified in both subject groups. B Comparison of number of differential features identified by three DE models. Colors indicate the number of PubMed search hits for each differential feature. C Full list of differential features identified by at least one but not all DE models. Features with different levels of PubMed literature support are placed in three groups. D Example feature identified as differential by DNA+Taxa model but not by DNA model. y-axis shows the RNA abundances regressing out DNA and Taxa (left) or DNA (right), as well as covariates of age and antibiotic status. FDRs of statistical tests are indicated on the top. E Example feature identified as differential by DNA+Taxa model but not by Taxa model. y-axis shows the RNA abundances regressing out DNA and Taxa (left) or Taxa (right), as well as covariates of age and antibiotic status. FDRs of statistical tests are indicated on the top

Back to article page