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Fig. 9 | BMC Microbiology

Fig. 9

From: Irinotecan-gut microbiota interactions and the capability of probiotics to mitigate Irinotecan-associated toxicity

Fig. 9

Representative photomicrographs of caspase-3 immune-stained colon sections (scale bar, 50 μm); A Control, showing normal no immune expression. B, C, D and E L. acidophilus, L. plantarum, L. rhamnosus and probiotic mixture treated respectively, showing no caspase-3 expression. F Irinotecan, showing strong positive caspase-3 immune expression (arrow). G Irinotecan + L. acidophilus, showing a reduced number of brown staining positive cells. H Irinotecan + L. plantarum showing weak expression of caspase-3 (arrow). I Irinotecan + L. rhamnosus, showing moderate immune expression (arrow) (J) Irinotecan + probiotic mixture, showing no caspase-3 immune expression

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