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Table 1 Baseline characteristics of patients with biopsy-proven fibrosis

From: Human liver microbiota modeling strategy at the early onset of fibrosis

Characteristics

All patients N = 82

Stage F0 N = 34

Stage F1 N = 37

Stage F2 N = 11

p Value F0vsF1

p Value F2vsF0

p Value F2vsF1

Age (years)

41.50 ± 11.52

39.5 ± 12.77

39 ± 9.53

50 ± 9.15

0.99

0.16

0.03*

Female (n)

47 (57%)

15 (18%)

26 (32%)

6 (7.3%)

0.65

0.99

0.97

Height (m)

1.67 ± 0.08

1.67 ± 0.08

1.7 ± 0.08

1.62 ± 0.07

0.99

0.61

0.14

Smoker (n)

22 (27%)

10 (12%)

10 (12%)

2 (3%)

0.99

0.99

0.97

Weight (kg)

118.5 ± 23.99

120 ± 22.55

118 ± 21.59

115.8 ± 35.77

0.99

0.99

0.97

BMI (kg/m2)

42.65 ± 7.73

43.25 ± 6.9

41.6 ± 7.2

41.52 ± 11.41

0.99

0.99

0.97

Waist (cm)

121 ± 18.37

124.5 ± 19.4

120 ± 15.61

120 ± 24.12

0.99

0.99

0.99

Blood Glucose (mg/dl)

95.7 ± 25.76

95 ± 27.46

99 ± 21.22

95 ± 34.63

0.99

0.99

0.97

Treated Diabetes (n)

7 (8.5%)

1 (1.2%)

2 (2%)

4 (4.7%)

0.99

0.02 *

0.027 *

Systolic (mm Hg)

130 ± 19.47

130.5 ± 20.76

124 ± 17.43

134 ± 18.45

0.65

0.99

0.73

Diastolic (mm Hg)

80.0 ± 11.59

80.5 ± 11.4

75 ± 10.31

90 ± 15.3

0.88

0.99

0.97

Treated Hypertension (n)

20 (24%)

8 (9.7%)

5 (6%)

7 (8.2%)

0.99

0.15

0.027 *

Treated Dyslipidemia (n)

6 (7.3%)

2 (2%)

3 (3.6%)

1 (1.2%)

0.99

0.99

0.99

Total Cholesterol (mg/dL)

189.1 ± 39.78

190.0 ± 36.93

200.0 ± 43.11

167.0 ± 38.71

0.99

0.99

0.97

HDL Cholesterol (mg/dL)

43.91 ± 13.38

47 ± 11.73

43 ± 13.48

42 ± 16.62

0.99

0.61

0.97

GOT (U/l)

20.85 ± 17.56

18.50 ± 18.14

22 ± 18.97

22 ± 7.54

0.99

0.99

0.97

GPT (U/l)

27.50 ± 25.23

23.50 ± 17.50

29 ± 31.91

30 ± 14.16

0.65

0.99

0.97

GGT (U/l)

29 ± 23.04

27.50 ± 18.04

30 ± 25.84

32 ± 23.3

0.65

0.61

0.99

HCT (%)

41 ± 4.03

40 ± 4.09

41.1 ± 3.05

40.5 ± 6.13

0.99

0.99

0.94

Leukocytes (G/L)

7.84 ± 2.63

7.48 ± 2.4

8.1 ± 2.39

7.8 ± 3.7

0.99

0.61

0.97

Neutrophils (G/L)

5 ± 2.44

4.8 ± 2.36

5.15 ± 2.28

5.3 ± 3.2

0.99

0.99

0.99

  1. Statistical significance (ANOVA) is noted with * when p < 0.05