Fig. 4

Principal Coordinates Analyses of the beta diversity of the bacterial DNA profiles of placental and vaginal/vaginal-rectal samples in placental microbiota studies

Prior published studies were included if vaginal or vaginal-rectal samples were sequenced and made publicly available alongside placental samples. The top ten ASVs shared between placental samples and technical controls, and the top ten ASVs in vaginal samples are plotted at their weighted average positions in the ordination space (grey diamonds) and their genus level classifications are noted. Agglomerated genus level classifications were plotted for the Liu dataset instead of ASVs since no ASVs were greater than 1% mean relative abundance across placental samples. Asterisks indicate ASV sequence genus level classifications which were assigned by NCBI BLAST with the highest percent identity in excess of 95%.