Fig. 3

Principal Coordinates Analyses of the beta diversity of bacterial DNA profiles between placental samples and technical controls in published placental microbiota studies

Studies were included if technical controls were sequenced and made publicly available to account for background DNA contamination. Beta diversity between placental (red open circles) and technical control (black open circles) samples is illustrated by study in PCoA plots based on the Bray-Curtis dissimilarity index. Genus level classifications of the top ten ASVs in placental samples and technical controls by total reads are plotted at their weighted average positions (grey diamonds). Asterisks indicate ASV sequence genus level classifications which were assigned by NCBI BLAST with the highest percent identity in excess of 95%.