Table 2 Molecular weight and druggability characterization of the predicted targets
Target Protein Name | Template Coverage / Identity | QMEAN Z-Scores | QMEANDisCo Scores | Ramachandran Score | Total Pockets | Highly Druggable | M. Wt (≤ 110 KDa) |
|---|---|---|---|---|---|---|---|
STY0490 ATP-dependent CLP protease proteolytic subunit clpP | 6nb1.1.A 0.95 / 99.03% | 0.70 | 0.85 ± 0.05 | 94.3% | 108 | 11 | 21.51KDa |
STY2284 Imidazole glycerol phosphate synthase hisH | 4gud.1.A 0.90 / 61.03% | −1.25 | 0.85 ± 0.06 | 89.9% | 6 | 1 | 21.71 KDa |
STY3473 7,8-dihydropteroate synthase folP | 3tzf.1.A 0.98 / 74.18% | 0.53 | 0.88 ± 0.05 | 90.3% | 12 | 1 | 30.52 KDa |
STY4091 2,3-bisphosphoglycerate-independent phosphoglycerate mutase gpmI | 5vpu.1.A 0.99 / 62.33% | −0.78 | 0.87 ± 0.05 | 94.8% | 15 | 2 | 55.56 KDa |