Skip to main content

Table 6 Kinetic parameters of free and Dextran-CDA conjugates from A. niger

From: Aspergillus Niger thermostable Cytosine deaminase-dextran conjugates with enhanced structure stability, proteolytic resistance, and Antiproliferative activity

Substrate

Free CDA

Dextran- CDA

Km

(mM)

Vmax

(μmol/mg/ min)

Kcat

(S−1)

Kcat/Km

(mM1 s−1)

Km

(mM)

Vmax

(μmol/mg/min)

Kcat

(s−1)

Kcat/Km

(mM−1S−1)

Cytosine

0.36

333.33

0.077

0.22

0.77

384.61

0.089

0.12

5-Flurocytosine

0.22

400.00

0.093

0.42

0.15

384.61

0.089

0.60