Skip to main content

Table 5 Relative activity of both free and Dextran-CDA conjugates in response to different general blocker and inhibitors

From: Aspergillus Niger thermostable Cytosine deaminase-dextran conjugates with enhanced structure stability, proteolytic resistance, and Antiproliferative activity

Inhibitors and amino acid suicide analogues.

Relative activity % free CDA

Relative activity % of CDA-Dextran conjugates

Control

100.00

100.00

DTNB

8.71

46.71

H2O2

6.22

60.53

MBTH

24.90

55.26

Hydroxylamine

9.54

37.50

Guanidine thiocyanate

16.60

41.45

Iodoacetamide

8.30

41.45

Apo-CDA

60.70

74.80

FeCl3

87.97

82.24

KCl

92.95

90.13

CaCl2

79.67

59.21

CuSo4

34.02

61.84

BaCl2

77.59

84.21

HgCl2

38.17

46.97

K2Cr2O7

43.57

41.05

AlCl3

66.39

77.63

NaCl

33.86

47.37