Fig. 2

Based on gut microbial composition and differential analysis in patients with Hashimoto’s thyroiditis at different stages of development. A Circos sample and species relationship diagram: The left half circle represents the species composition in the sample; the different color of outer ribbon: different samples (HCA, HT1A, HT2A); inner ribbon: bacteria species; the length of the ribbon: the abundance of the corresponding species. The right half circle: the bacteria abundance in different samples; the outer ribbon: bacteria species; the inner ribbon: different samples (HCA, HT1A, HT2A), length of the ribbon: the abundance of the corresponding bacteria species. B Analysis of gut microbial community composition of different samples: The ordinate is the sample name; the abscissa is the proportion of a species in the sample; the different-colored columns represent different species; and the length of the column represents the proportion of a species. C PLS-DA sample group analysis: The dots with different colors or shapes represent the sample groups under different environments or conditions, and Comp1 and Comp2 represent the suspected influencing factors affecting the deviation in the microbial composition of the two groups of samples. D Analysis of the significant differences between groups based on the community abundance data in the sample and the Kruskal–Wallis rank sum test: The Y-axis represents the species names at certain taxonomic levels; the X-axis represents the average relative abundance of species in different groups; and different-colored bars indicate different grouping. The p values are on the far right, where *p ≤ 0.05 and ***p ≤ 0.001