Table 1 Docking energy of blaOXA-1, blaOXA-23, blaOXA-58, blaOXA-143, blaOXA-24, IMP-1, recA and NMD-1 against carbapenem antibiotics
From: Carbapenem resistance gene crisis in A. baumannii: a computational analysis
Proteins | Binding Energies (Kcal/mol) | ||
|---|---|---|---|
Doripenem | Imipenem | Meropenem | |
blaOXA-51 | -5.2 | -5.5 | -5.2 |
blaOXA-23 | -3.4 | -4.3 | -2.3 |
blaOXA-58 | -4.9 | -4.2 | -4.9 |
IMP-1 | -5.3 | -4.5 | -5.7 |
rec A | -3.8 | -4.9 | -3.6 |
blaOXA-143 | -2.5 | -3 | -1.9 |
blaOXA-24 | -5.5 | -3.9 | -4.4 |
NMD-1 | -1.5 | -4 | -3.3 |