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Fig. 4 | BMC Microbiology

Fig. 4

From: Meta-analysis of 16S rRNA microbial data identified alterations of the gut microbiota in COVID-19 patients during the acute and recovery phases

Fig. 4

Differential gut microbial composition between RP/post-RP and non-COV (a) at genus level, and (b) at species level. Heatmap showed log (OR) of relative abundances of bacterial taxa between RP/post-RP and non-COV across each study. The bacterial taxa unavailable in a particular study were in white in heatmap. Forest plot indicated pooled log (OR) estimate and 95% CI of relative abundances of bacterial taxa between RP/post-RP and non-COV across all studies included. Log (OR) estimates were from GAMLSS-BEZI and Random Effects Meta-analysis. Only bacterial taxa with pooled P of pooled log (OR) estimates below 0.05 were displayed. Pooled log (OR) estimates with FDR-adjusted pooled P < 0.1 were showed as red triangles. Log (OR) > 0 denoted an increase and log (OR) < 0 denoted a decrease of taxa relative abundance in RP/post-RP compared with non-COV. RP, samples derived from COVID-19 recovered patients who with clearance of SARS-CoV-2 RNA (negative conversion of viral RNA) within one month; those with negative conversion of viral RNA more than three months were especially grouped as post-RP; non-COV, samples derived from non-COVID-19 individuals

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