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Fig. 4 | BMC Microbiology

Fig. 4

From: Microbiological characteristics of different tongue coatings in adults

Fig. 4

Discrepancies of co-occurrence networks of the four different tongue coating types ABC and D The complex nature of inter microbial interactions in the ecological community of each tongue coating was characterized by co-occurrence networks using graphs. Main groups of co-occurrence species are presented in different colours, and smaller groups are shown in grey. Networks of species in the four tongue coatings are identified by positive and negative correlations among the dominant bacteria. Red line indicates positive correlation and blue line indicates negative correlation. Only the bacterial connections (edges) larger than cut-offs (correlation values > 0.4) are retained. Each node in the network indicates a species. The size of each node is proportional to the relative abundance of each species. Nodes in red color show driver microbes which significantly contributed to the separation of the networks (NESH-score value of > 2). E, F and G Network view: All nodes belonging to the same community are randomly assigned similar colors, and gray nodes represent nodes existing in both case and control subnets. The node size is directly proportional to its nesh score. If the nesh score of a node is case > control, it will be marked in red. Therefore, a large red node can be regarded as a driving node. For edges, red indicates the interaction that exists only in the case subnet, green indicates the interaction that exists only in the control subnet, and blue indicates the interaction that exists in both subnets

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