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Table 2 Antibiotic susceptibilities and linezolid resistance mechanisms of linezolid-resistant Staphylococcus capitis isolates

From: Mechanisms of linezolid resistance in Staphylococcus capitis with the novel mutation C2128T in the 23S rRNA gene in China

Isolate

MIC (mg/L)

Genetic resistance markers

LZD

P

OXA

CN

CIP

LEV

MXF

E

DA

QD

VA

TE

TGC

RA

SXT

cfr

23S rRNA

L3

L4

L22

701

≥256

≥0.5

≥4

≥16

≥8

4

2

≥8

2

1

≤0.5

1

0.25

≤0.5

20

+

C2128, G2600T

–

–

–

703

≥256

≥0.5

≥4

≥16

≥8

≥8

2

≥8

≥8

2

≤0.5

2

0.5

≤0.5

20

+

C2128T, G2600T

–

–

–

708

≥256

≥0.5

≥4

≥16

≥8

4

2

≥8

≥8

2

≤0.5

2

0.5

≤0.5

20

+

C2128T, G2600T

–

–

–

709

≥256

≥0.5

≥4

≥16

≥8

4

2

≥8

≥8

2

≤0.5

2

0.5

≤0.5

20

+

C2128T, G2600T

–

–

–

  1. MIC Minimum inhibitory concentration, LZD Linezolid, P Penicillin, OXA Oxacillin, CN Gentamicin, CIP Ciprofloxacin, LEV levofloxacin, MXF Moxifloxacin, E Erythromycin, DA Clindamycin, QD Quinupristin/dalfopristin, VA Vancomycin, TE Tetracycline, TGC Tigecycline, RA Rifampicin, SXT Trimethoprim/sulfamethoxazole (19 mg/L /1 mg/L)
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BMC Microbiology

ISSN: 1471-2180

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