Table 4 CARD database annotation statistics
Gene | Gene ID | ARO ID | Resistance | Resistance Mechanism |
|---|---|---|---|---|
H-NS | GE001452 | 3,000,676 | Penam, macrolide, cephalosporin, cephamycin, tetracycline, and fluoroquinolone | Antibiotic efflux |
CRP | GE000225 | 3,000,518 | Penam, macrolide, and fluoroquinolone | Antibiotic efflux |
adeF | GE004010 | 3,000,777 | Tetracycline and fluoroquinolone | Antibiotic efflux |
floR | GE005069 | 3,002,705 | Phenicol | Antibiotic efflux |
tet(59) | GE005065 | 3,004,441 | Tetracycline | Antibiotic efflux |
PBP3 | GE002506 | 3,004,446 | Carbapenem, cephalosporin, monobactam, penam, and cephamycin | Antibiotic target alteration |
parE | GE002526 | 3,003,316 | Fluoroquinolone | Antibiotic target alteration |
mprF | GE000717 | 3,003,324 | Peptide | Antibiotic target alteration |
sul1 | GE005011 | 3,000,410 | Sulfone and sulfonamide | Antibiotic target replacement |
sul2 | GE005074 | 3,000,412 | Sulfone and sulfonamide | Antibiotic target replacement |
varG | GE003041 | 3,004,289 | Carbapenem | Antibiotic inactivation |
APH(6)-Id | GE005072 | 3,002,660 | Aminoglycoside | Antibiotic inactivation |
APH(3'')-Ib | GE005073 | 3,002,639 | Aminoglycoside | Antibiotic inactivation |
aadA16 | GE005009 | 3,002,616 | Aminoglycoside | Antibiotic inactivation |
arr-3 | GE005007 | 3,002,848 | Rifamycin | Antibiotic inactivation |
TEM-1 | GE005062 | 3,000,873 | Penam, penem, cephalosporin, and monobactam | Antibiotic inactivation |